公开(公告)号：EP0376746A3

公开(公告)日：1990-08-22

申请号：EP89313687.9

申请日：1989-12-29

申请人： THE WISTAR INSTITUTE

发明人： Linnenbach, Alban, Dr.

IPC分类号： C12N15/12 ,  C12P21/02 ,  C12P21/08 ,  C12N5/10 ,  A61K37/02 ,  C07K13/00 ,  C12Q1/68 ,  A61K39/395

CPC分类号： C07K14/4748 ,  A61K38/00 ,  A61K39/00 ,  C07K16/3046 ,  C07K16/4266 ,  Y10S530/828

摘要： A tumor-associated antigen has been discovered which shares sequence homology with both thyroglobulin type I and interleukin-2 receptors. The antigen is highly expressed in pancreatic carcinoma cells. The antigen is similar to a previously described tumor-associated antigen found in colorectal carcinoma cells. The gene for the antigen is fully sequenced and described here.

摘要翻译： 已经发现肿瘤相关抗原与I型和白介素-2受体的甲状腺球蛋白共享序列同源性。 抗原在胰腺癌细胞中高度表达。 抗原类似于在结肠直肠癌细胞中发现的先前描述的肿瘤相关抗原。 抗原的基因在此完全测序并描述。

公开(公告)号：EP0376746A2

公开(公告)日：1990-07-04

申请号：EP89313687.9

申请日：1989-12-29

申请人： THE WISTAR INSTITUTE

发明人： Linnenbach, Alban, Dr.

IPC分类号： C12N15/12 ,  C12P21/02 ,  C12P21/08 ,  C12N5/10 ,  A61K37/02 ,  C07K13/00 ,  C12Q1/68 ,  A61K39/395

CPC分类号： C07K14/4748 ,  A61K38/00 ,  A61K39/00 ,  C07K16/3046 ,  C07K16/4266 ,  Y10S530/828

摘要： A tumor-associated antigen has been discovered which shares sequence homology with both thyroglobulin type I and interleukin-2 receptors. The antigen is highly expressed in pancreatic carcinoma cells. The antigen is similar to a previously described tumor-associated antigen found in colorectal carcinoma cells. The gene for the antigen is fully sequenced and described here.

摘要翻译： 已经发现肿瘤相关抗原与I型和白介素-2受体的甲状腺球蛋白共享序列同源性。 抗原在胰腺癌细胞中高度表达。 抗原类似于在结肠直肠癌细胞中发现的先前描述的肿瘤相关抗原。 抗原的基因在此完全测序并描述。