PRODUCTION METHOD FOR CHEMICALS BY CONTINUOUS FERMENTATION
    1.
    发明公开
    PRODUCTION METHOD FOR CHEMICALS BY CONTINUOUS FERMENTATION 审中-公开
    HERMTELLUNGSVERFAHRENFÜRCHEMIKALIEN DURCH KONTINUIERLICHE FERMENTIERUNG

    公开(公告)号:EP2617832A1

    公开(公告)日:2013-07-24

    申请号:EP11825009.1

    申请日:2011-09-05

    摘要: In the production and collection of a product through fermentation using a separation membrane, it becomes possible to retain filter performance for the high-concentration culturing of a microbe mixture, and at the same time control microbe concentrations, by a method for producing chemicals through continuous fermentation, including washing a membrane with a washing liquid supplied from a permeate side of a membrane unit in a continuous fermentation including: filtering a culture medium containing a fermentation feedstock, a chemical and a microbe or a cultured cell through a separation membrane; collecting the chemical from a filtrate; retaining or refluxing unfiltered remains in the culture medium; and adding a fermentation feedstock to the culture medium, in which the washing liquid is high-temperature water having a temperature higher than a temperature of the culture medium and of 150°C or less, and a concentration of the microbe in a fermenter is controlled by supplying the washing liquid.

    摘要翻译: 在通过使用分离膜的发酵生产和收集产品时,可以保持微生物混合物的高浓度培养的过滤性能,同时通过连续生产化学品的方法控制微生物浓度 发酵,包括在连续发酵中从膜单元的渗透侧供给的洗涤液洗涤膜,包括:通过分离膜过滤含有发酵原料,化学品和微生物或培养的细胞的培养基; 从滤液中收集化学物质; 在培养基中保留或回流未过滤的残留物; 并将发酵原料加入到培养基中,其中洗涤液是温度高于培养基温度的150℃或更低的高温水,并控制发酵罐中微生物的浓度 通过供给洗涤液。

    HOLLOW-FIBER MEMBRANE MODULE
    2.
    发明公开
    HOLLOW-FIBER MEMBRANE MODULE 审中-公开
    HOHLFASERMEMBRANMODUL

    公开(公告)号:EP1974800A1

    公开(公告)日:2008-10-01

    申请号:EP06834421.7

    申请日:2006-12-11

    IPC分类号: B01D63/02 B01D63/00 B01D63/04

    摘要: A hollow-fiber membrane module which comprises: a cylindrical vessel having openings at the upper and lower ends; hollow-fiber membrane bundles each comprising many hollow-fiber membranes and extending upward/downward in the cylindrical vessel; a hollow-fiber fixing member which is disposed at an upper-end part of the hollow-fiber membranes and fixes the hollow-fiber membranes so as to keep the hollow of each hollow-fiber membrane open; and a hollow-fiber membrane closing member which is disposed at a lower-end part of the hollow-fiber membranes and closes the hollow of each hollow-fiber membrane, wherein the hollow-fiber membrane fixing member is fixed to the cylindrical vessel in such a state that the fixing member closes the upper-end opening of the cylindrical vessel. In the hollow-fiber membrane module, at least part of the peripheral wall of the cylindrical vessel comprises a porous member, and the peripheral wall in a lower part of the cylindrical vessel has an average rate of hole area of 25% or lower.

    摘要翻译: 一种中空纤维膜组件,包括:在上端和下端具有开口的圆柱形容器; 中空纤维膜束各自包含许多中空纤维膜并在圆柱形容器中向上/向下延伸; 中空纤维固定构件,其设置在中空纤维膜的上端部并固定中空纤维膜,以使每个中空纤维膜的中空保持打开; 以及中空纤维膜闭合部件,其设置在中空纤维膜的下端部并封闭每个中空纤维膜的中空部,其中,中空纤维膜固定部件固定在圆筒状容器上 固定构件封闭圆柱形容器的上端开口的状态。 在中空纤维膜组件中,圆筒形容器的周壁的至少一部分包括多孔构件,圆筒形容器的下部的周壁的平均孔面积率为25%以下。

    FRESH WATER GENERATOR
    4.
    发明公开
    FRESH WATER GENERATOR 审中-公开
    FRISCHWASSERGENERATOR

    公开(公告)号:EP2468685A1

    公开(公告)日:2012-06-27

    申请号:EP10809766.8

    申请日:2010-05-25

    IPC分类号: C02F1/44 B01D61/58

    摘要: Disclosed is a fresh water generator for fresh water production, which is effective to prevent a membrane life from becoming worse by suppressing the load on the membrane of a second semi-permeable membrane treatment facility (3) when the concentrated water produced by the treatment of a first semi-permeable membrane treatment facility (2), and water to be treated with different osmotic pressure there from are mixed and treated with the second semi-permeable membrane treatment facility (3) by the fresh water generator which comprises a means for storing the concentrated water produced from the first semi- permeable membrane treatment facility (2) and water (B) to be treated, which is separately supplied in a storage tank A (7) and a storage tank B (8) in such a manner that the flow rate (mixture ratio) of the concentrated water to the water (B) to be treated is maintained constant, and supplying the concentrated water and the water (B) to be treated from each of the storage tanks to the second semi-permeable membrane treatment facility (3) at a predetermined flow rate in at least a treatment process for treating water (A) to be treated with the first semi-permeable membrane treatment facility (2) so as to obtain fresh water.

    摘要翻译: 公开了一种用于淡水生产的淡水发生器,其通过抑制第二半透膜处理设备(3)的膜上的负荷来防止膜寿命变差,当通过处理产生的浓缩水 将第一半透膜处理设备(2)和不同渗透压处理的水与所述第二半渗透膜处理设备(3)混合并处理,所述净水器包括用于存储的装置 由第一半透膜处理设备(2)和待处理的水(B)产生的浓缩水分别供应在储罐A(7)和储罐B(8)中,使得 将待处理的浓缩水与水(B)的流量(混合比)保持恒定,并从每个储罐向第二个供给浓缩水和待处理水(B) 第二半透膜处理设备(3)至少在处理用第一半透膜处理设备(2)处理的水(A)的处理过程中以预定的流速获得淡水。

    HOLLOW FIBER MEMBRANE MODULE AND METHOD FOR PRODUCING CHEMICALS
    6.
    发明公开
    HOLLOW FIBER MEMBRANE MODULE AND METHOD FOR PRODUCING CHEMICALS 审中-公开
    HOLLFASERMEMBRANENMODUL UND VERFAHREN ZUR HERSTELLUNG VON CHEMIKALIEN

    公开(公告)号:EP2659957A1

    公开(公告)日:2013-11-06

    申请号:EP11853437.9

    申请日:2011-12-22

    摘要: Disclosed is a hollow fiber membrane module comprising a housing and a hollow fiber membrane filled in the housing, the space between the hollow fiber membrane and the housing being sealed with a sealing agent; wherein the hollow fiber membrane is made of a polysulfone based resin; a membrane surface average pore diameter is 5 nm or more and 500 nm or less; a pure water permeability coefficient under 50 kPa at 25°C is 0.05 m 3 /m 2 /hour or more and 5 m 3 /m 2 /hour or less; the sealing agent is at least one selected from a polyurethane resin and an epoxy resin; and a decrease in tensile strength after bringing the sealing agent into contact with saturated steam at 121°C for 24 hours is 25% or less. The present invention provides a hollow fiber membrane module which has sufficient durability against steam sterilization and maintains stable filtration property over a long period of time, and a method for producing a chemical substance by a continuous fermentation process, using the same.

    摘要翻译: 公开了一种中空纤维膜组件,其包括壳体和填充在壳体中的中空纤维膜,中空纤维膜和壳体之间的空间用密封剂密封; 其中所述中空纤维膜由聚砜基树脂制成; 膜表面平均孔径为5nm以上且500nm以下; 25℃下50kPa下的纯水渗透系数为0.05m 3 / m 2 /小时以上且5m 3 / m 2 /小时以下; 密封剂是选自聚氨酯树脂和环氧树脂中的至少一种; 使密封剂与121℃的饱和蒸气接触24小时后的拉伸强度降低为25%以下。 本发明提供一种中空纤维膜组件,其具有足够的耐蒸汽灭菌耐久性和长时间保持稳定的过滤性能的中空纤维膜组件,以及通过连续发酵工艺生产化学物质的方法。

    HOLLOW FIBER MEMBRANE MODULE
    7.
    发明公开
    HOLLOW FIBER MEMBRANE MODULE 审中-公开
    HOHLFASERMEMBRANMODUL

    公开(公告)号:EP2067521A1

    公开(公告)日:2009-06-10

    申请号:EP07807112.3

    申请日:2007-09-12

    IPC分类号: B01D63/02

    摘要: This invention provides a hollow fiber membrane module which can reduce pressure loss in discharging water within a module and can reduce operating power. A hollow fiber membrane bundle comprising a plurality of numbers of hollow fiber membranes are disposed within a cylindrical case having in its side face an opening part for the inflow/outflow of water, and the end of the hollow fiber membrane bundle is fixed by bonding at a position which is located in the axial direction of the cylindrical case at an outer position than the position of the opening part for the inflow/outflow of water on the side face of the cylindrical case. The hollow fiber membrane module is characterized in that a distribution cylinder provided with distribution holes is provided inward with respect to the opening part for the inflow/outflow of water on the side face of the cylindrical case and so as to surround the outer periphery of the hollow fiber membrane bundle, and grooves and/or corrugated protrusions are provided on the inner face of the distribution cylinder so as to be in communication with each other among the distribution holes.

    摘要翻译: 本发明提供一种中空纤维膜组件,其可以减少在模块内排放水中的压力损失并且可以降低操作功率。 将包含多个中空纤维膜的中空纤维膜束设置在圆筒形壳体内,其侧面具有用于水的流入/流出的开口部分,并且中空纤维膜束的端部通过粘合固定 位于圆柱形壳体的轴向方向上的位置处于比用于在圆筒形壳体的侧面上的水的流入/流出的开口部的位置的外部位置。 中空纤维膜组件的特征在于,设置有分配孔的分配筒相对于用于在筒状壳体的侧面上的水的流入/流出的开口部向内设置,以包围外筒的外周 中空纤维膜束,并且在分配筒的内表面上设置有槽和/或波纹状突起,以便在分配孔中彼此连通。

    METHOD FOR PRODUCING CHEMICAL BY CONTINUOUS FERMENTATION
    8.
    发明公开
    METHOD FOR PRODUCING CHEMICAL BY CONTINUOUS FERMENTATION 审中-公开
    VERFAHREN ZUR HERSTELLUNG EINER CHEMIKALIE DURCH KONTINUIERLICHE FERMENTIERUNG

    公开(公告)号:EP2650375A1

    公开(公告)日:2013-10-16

    申请号:EP11847535.9

    申请日:2011-12-08

    IPC分类号: C12P13/04 C12P13/00

    摘要: A method for producing a chemical through continuous fermentation, the method including:
    (a) culturing a cell in a culture medium in a fermentor to ferment a feedstock to produce a chemical;
    (b) conducting filtration of the culture medium by using a separation membrane module;
    (c) separating a permeate containing the chemical from the culture medium while retaining a non-permeated liquid in the fermentor, and
    (d) supplying a gas from at least one of a lower portion of the separation membrane module and a pipe communicating between the fermentor and the separation membrane module so as to adjust a gas linear velocity in the separation membrane module to 0.15 cm/s to 70 cm/s while supplying the separation membrane module with a liquid.

    摘要翻译: 一种通过连续发酵生产化学品的方法,所述方法包括:(a)在发酵罐中培养培养基中的细胞以发酵原料以生产化学品; (b)使用分离膜组件进行培养基的过滤; (c)将含有化学物质的渗透物从培养基中分离,同时将不渗透的液体保持在发酵罐中,和(d)从分离膜组件的下部中的至少一个供应气体,以及在 发酵罐和分离膜组件,以便在分离膜组件供给液体的同时将分离膜组件中的气体线速度调节至0.15cm / s至70cm / s。