专利检索 ap:("The Board of Trustees of the Leland Stanford Junior University") AND inv:"SMOLKE, Christina, D." 第 1 页

1.

发明公开
METHODS OF PRODUCING EPIMERASES AND BENZYLISOQUINOLINE ALKALOIDS 审中-公开

公开(公告)号：EP4253525A3

公开(公告)日：2023-10-18

申请号：EP23167022.5

申请日：2016-05-09

申请人： The Board of Trustees of the Leland Stanford Junior University

发明人： SMOLKE, Christina, D. , GALANIE, Stephanie , TRENCHARD, Isis , THODEY, Catherine , LI, Yanran

IPC分类号： C12N1/19 , C12N15/52 , C12N15/53

摘要： A method of epimerizing an (S) -1-benzylisoquinoline alkaloid to an (R) -1-benzylisoquinoline alkaloid is provided. The method comprises contacting the (S) -1-benzylisoquinoline alkaloid with at least one enzyme. Contacting the (S) -1-benzylisoquinoline alkaloid with the at least one enzyme converts the (S) -1-benzylisoquinoline alkaloid to an (R) -1-benzylisoquinoline alkaloid.

2.

发明公开
METHODS OF PRODUCING EPIMERASES AND BENZYLISOQUINOLINE ALKALOIDS 审中-公开

公开(公告)号：EP4253525A2

公开(公告)日：2023-10-04

申请号：EP23167022.5

申请日：2016-05-09

申请人： The Board of Trustees of the Leland Stanford Junior University

发明人： SMOLKE, Christina, D. , GALANIE, Stephanie , TRENCHARD, Isis , THODEY, Catherine , LI, Yanran

IPC分类号： C12N1/19 , C12N15/52 , C12N15/53

摘要： A method of epimerizing an (S) -1-benzylisoquinoline alkaloid to an (R) -1-benzylisoquinoline alkaloid is provided. The method comprises contacting the (S) -1-benzylisoquinoline alkaloid with at least one enzyme. Contacting the (S) -1-benzylisoquinoline alkaloid with the at least one enzyme converts the (S) -1-benzylisoquinoline alkaloid to an (R) -1-benzylisoquinoline alkaloid.