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1.发明授权
公开(公告)号：EP2032129B1
公开(公告)日：2014-01-29
申请号：EP07735601.2
申请日：2007-04-20
发明人： MARTIN, Kelly, Lee , KHANOLKAR, Jayant, Eknath , GLEDHILL, Douglas, William , CRISS, Susan, Elaine , RAMJI, Niranjan , COSTEINES, Elaine, Rose
IPC分类号： A61K31/137 , A61P11/02 , A61K9/00 , A61K47/26
CPC分类号： A61K31/137 , A61K31/473 , A61K31/485 , A61K31/495 , A61K31/519 , A61K31/522 , A61K31/55 , A61K31/616 , A61K45/06 , A61K2300/00
摘要： Disclosed are compositions including phenylephrine, its free and addition salt forms, and mixtures thereof, alone, or in combination with other pharmaceutical actives. The compositions have a pH of about 2 to about 5 and are substantially free of aldehydes. Also disclosed are methods of treating respiratory illness through administration of a composition comprising phenylephrine, its free and addition salt forms, and mixtures thereof alone, or in combination with other pharmaceutical actives, wherein the composition has a pH of from about 2 to about 5 and is substantially free of aldehydes.
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2.发明公开
公开(公告)号：EP3515397A1
公开(公告)日：2019-07-31
申请号：EP17772277.4
申请日：2017-09-15
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公开(公告)号：EP3283053A1
公开(公告)日：2018-02-21
申请号：EP16717784.9
申请日：2016-04-12
摘要： A multi-layered cosmetic composition suitable for topical application is provided. The composition comprises an oil layer comprising at least about 5%, by weight of the composition, of natural oil; and an aqueous layer, comprising at least about 0.01%, by weight of the composition, of a polymer selected from the group consisting of a polysaccharide, sodium hyaluronate, or a combination thereof. The multi-layered cosmetic composition is free of surfactant.
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公开(公告)号：EP2046289B1
公开(公告)日：2014-01-29
申请号：EP07735602.0
申请日：2007-04-20
发明人： MARTIN, Kelly, Lee , KHANOLKAR, Jayant, Eknath , GLEDHILL, Douglas, William , CRISS, Susan, Elaine , RAMJI, Niranjan , COSTEINES, Elaine, Rose , HUETTER, Thomas, Edward , IYER, Radhika, R. , ANNESS, Daren, K.
IPC分类号： A61K31/137 , A61P11/02
CPC分类号： A61K31/485 , A61J1/05 , A61K9/0095 , A61K9/08 , A61K31/137 , A61K31/167 , A61K31/473 , A61K31/495 , A61K31/519 , A61K31/522 , A61K31/55 , A61K31/616 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/22 , A61K47/26 , A61K2300/00
摘要： A stable liquid composition in a clear bottle where the composition contains, at least, phenylephrine and acetaminophen. The composition is substantially free of aldehydes and has a pH from 3.5 to 5. The clear bottle is a polyethylene terphthalate bottle.
摘要翻译： 澄清瓶中稳定的液体组合物，其中组合物至少含有去氧肾上腺素和对乙酰氨基酚。 该组合物基本上不含醛，pH值为3.5至5.透明瓶是聚对苯二甲酸乙二醇酯瓶。
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公开(公告)号：EP3283053B1
公开(公告)日：2020-05-13
申请号：EP16717784.9
申请日：2016-04-12
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6.发明公开
公开(公告)号：EP2032129A2
公开(公告)日：2009-03-11
申请号：EP07735601.2
申请日：2007-04-20
发明人： MARTIN, Kelly, Lee , KHANOLKAR, Jayant, Eknath , GLEDHILL, Douglas, William , CRISS, Susan, Elaine , RAMJI, Niranjan , COSTEINES, Elaine, Rose
IPC分类号： A61K31/137
CPC分类号： A61K31/137 , A61K31/473 , A61K31/485 , A61K31/495 , A61K31/519 , A61K31/522 , A61K31/55 , A61K31/616 , A61K45/06 , A61K2300/00
摘要： Disclosed are compositions including phenylephrine, its free and addition salt forms, and mixtures thereof, alone, or in combination with other pharmaceutical actives. The compositions have a pH of about 2 to about 5 and are substantially free of aldehydes. Also disclosed are methods of treating respiratory illness through administration of a composition comprising phenylephrine, its free and addition salt forms, and mixtures thereof alone, or in combination with other pharmaceutical actives, wherein the composition has a pH of from about 2 to about 5 and is substantially free of aldehydes.
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公开(公告)号：EP1216044A1
公开(公告)日：2002-06-26
申请号：EP00970493.3
申请日：2000-09-26
IPC分类号： A61K31/485 , A61K9/00 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/20 , A61K47/22 , A61K47/00
CPC分类号： A61K9/0095 , A61K9/0056 , A61K9/006 , A61K31/485 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , A61K47/20 , A61K47/22
摘要： The present invention pertains to improved stability of compositions that deliver pharmaceutical active ingredients. These compositions have exceptional stability when used in various product forms including liquid elixirs placed into the mouth and eventually swallowed, or can be delivered via liquid-filled lozenges, metered liquid dosing devices, atomizers and liquid-releasing, edible capsules. Such compositions are particularly useful for treating symptoms associated with respiratory illnesses.
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