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公开(公告)号：EP2046289B1
公开(公告)日：2014-01-29
申请号：EP07735602.0
申请日：2007-04-20
发明人： MARTIN, Kelly, Lee , KHANOLKAR, Jayant, Eknath , GLEDHILL, Douglas, William , CRISS, Susan, Elaine , RAMJI, Niranjan , COSTEINES, Elaine, Rose , HUETTER, Thomas, Edward , IYER, Radhika, R. , ANNESS, Daren, K.
IPC分类号： A61K31/137 , A61P11/02
CPC分类号： A61K31/485 , A61J1/05 , A61K9/0095 , A61K9/08 , A61K31/137 , A61K31/167 , A61K31/473 , A61K31/495 , A61K31/519 , A61K31/522 , A61K31/55 , A61K31/616 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/22 , A61K47/26 , A61K2300/00
摘要： A stable liquid composition in a clear bottle where the composition contains, at least, phenylephrine and acetaminophen. The composition is substantially free of aldehydes and has a pH from 3.5 to 5. The clear bottle is a polyethylene terphthalate bottle.
摘要翻译： 澄清瓶中稳定的液体组合物，其中组合物至少含有去氧肾上腺素和对乙酰氨基酚。 该组合物基本上不含醛，pH值为3.5至5.透明瓶是聚对苯二甲酸乙二醇酯瓶。
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2.发明授权
公开(公告)号：EP2032129B1
公开(公告)日：2014-01-29
申请号：EP07735601.2
申请日：2007-04-20
发明人： MARTIN, Kelly, Lee , KHANOLKAR, Jayant, Eknath , GLEDHILL, Douglas, William , CRISS, Susan, Elaine , RAMJI, Niranjan , COSTEINES, Elaine, Rose
IPC分类号： A61K31/137 , A61P11/02 , A61K9/00 , A61K47/26
CPC分类号： A61K31/137 , A61K31/473 , A61K31/485 , A61K31/495 , A61K31/519 , A61K31/522 , A61K31/55 , A61K31/616 , A61K45/06 , A61K2300/00
摘要： Disclosed are compositions including phenylephrine, its free and addition salt forms, and mixtures thereof, alone, or in combination with other pharmaceutical actives. The compositions have a pH of about 2 to about 5 and are substantially free of aldehydes. Also disclosed are methods of treating respiratory illness through administration of a composition comprising phenylephrine, its free and addition salt forms, and mixtures thereof alone, or in combination with other pharmaceutical actives, wherein the composition has a pH of from about 2 to about 5 and is substantially free of aldehydes.
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公开(公告)号：EP2254541A1
公开(公告)日：2010-12-01
申请号：EP09723507.1
申请日：2009-03-17
CPC分类号： A61J1/035 , A61J7/0084 , A61J2205/20 , A61J2205/30 , A61J2205/40 , A61J2205/50
摘要： A customizable dosing system is provided, comprising a primary container comprising at least one enclosure, the enclosure containing a dosage unit comprising an active; indicia for selection or deselection of one or more of the dosage units and actives; wherein the indicia enables a user to select a system and one or more dosage units and actives appropriate to a user's needs. Also provided are methods of customizing dosage and treatment, and kits containing a customizable dosing system and one or more complimentary products.
摘要翻译： 提供可定制的剂量系统，其包括包含至少一个外壳的主容器，所述外壳包含含有活性剂的剂量单位; 用于选择或取消一个或多个剂量单位和活性物质的标记; 其中标记使用户能够选择适合用户需求的系统和一个或多个剂量单位和活性物质。 还提供了定制剂量和治疗方法，以及包含可定制给药系统和一种或多种免费产品的试剂盒。
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4.发明授权LIQUID COMPOSITIONS COMPRISING PHENYLEPHRINE AND ACETAMINOPHEN AND THEIR USE FOR THE TREATMENT OF RESPIRATORY ILLNESS 有权液体组合物，包含去氧肾上腺素和乙酰氨基酚和它们用于呼吸系统疾病的治疗
公开(公告)号：EP2012765B2
公开(公告)日：2018-04-11
申请号：EP07735699.6
申请日：2007-04-27
IPC分类号： A61K31/137 , A61K31/167 , A61K31/485 , A61K47/10 , A61K47/12 , A61K47/20 , A61P11/02 , A61P11/10
CPC分类号： A61K9/0095 , A61K31/137 , A61K31/16 , A61K31/167 , A61K31/192 , A61K31/485 , A61K31/519 , A61K31/522 , A61K31/55 , A61K31/616 , A61K2300/00
摘要： Disclosed are compositions including phenylephrine, its salts, and mixtures thereof, in combination with acetaminophen; and optionally in combination with additional pharmaceutical actives. The compositions have a pH of about 6.5 to about 7.5 and may be substantially free of aldehydes. The invention also provides a method of stabilizing phenylephrine. Also disclosed are methods of treating respiratory illness through administration of a composition comprising phenylephrine, its salts, and mixtures thereof, in combination with acteaminophen; and optionally in combination with additional pharmaceutical actives, wherein the composition has a pH of from about 6.5 to about 7.5 and may be substantially free of aldehydes.
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5.发明授权LIQUID COMPOSITIONS COMPRISING PHENYLEPHRINE AND ACETAMINOPHEN AND THEIR USE FOR THE TREATMENT OF RESPIRATORY ILLNESS 有权液体化合物含肾上腺素和ACTETAMINOPHEN及其用于呼吸系统疾病的治疗
公开(公告)号：EP2012765B1
公开(公告)日：2015-03-25
申请号：EP07735699.6
申请日：2007-04-27
IPC分类号： A61K31/137 , A61K31/167 , A61K31/485 , A61K47/10 , A61K47/12 , A61K47/20 , A61P11/02 , A61P11/10
CPC分类号： A61K9/0095 , A61K31/137 , A61K31/16 , A61K31/167 , A61K31/192 , A61K31/485 , A61K31/519 , A61K31/522 , A61K31/55 , A61K31/616 , A61K2300/00
摘要： Disclosed are compositions including phenylephrine, its salts, and mixtures thereof, in combination with acetaminophen; and optionally in combination with additional pharmaceutical actives. The compositions have a pH of about 6.5 to about 7.5 and may be substantially free of aldehydes. The invention also provides a method of stabilizing phenylephrine. Also disclosed are methods of treating respiratory illness through administration of a composition comprising phenylephrine, its salts, and mixtures thereof, in combination with acteaminophen; and optionally in combination with additional pharmaceutical actives, wherein the composition has a pH of from about 6.5 to about 7.5 and may be substantially free of aldehydes.
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6.发明公开
公开(公告)号：EP2032129A2
公开(公告)日：2009-03-11
申请号：EP07735601.2
申请日：2007-04-20
发明人： MARTIN, Kelly, Lee , KHANOLKAR, Jayant, Eknath , GLEDHILL, Douglas, William , CRISS, Susan, Elaine , RAMJI, Niranjan , COSTEINES, Elaine, Rose
IPC分类号： A61K31/137
CPC分类号： A61K31/137 , A61K31/473 , A61K31/485 , A61K31/495 , A61K31/519 , A61K31/522 , A61K31/55 , A61K31/616 , A61K45/06 , A61K2300/00
摘要： Disclosed are compositions including phenylephrine, its free and addition salt forms, and mixtures thereof, alone, or in combination with other pharmaceutical actives. The compositions have a pH of about 2 to about 5 and are substantially free of aldehydes. Also disclosed are methods of treating respiratory illness through administration of a composition comprising phenylephrine, its free and addition salt forms, and mixtures thereof alone, or in combination with other pharmaceutical actives, wherein the composition has a pH of from about 2 to about 5 and is substantially free of aldehydes.
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