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公开(公告)号：EP2814835B1
公开(公告)日：2019-04-10
申请号：EP13748609.8
申请日：2013-02-14
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公开(公告)号：EP2405918A1
公开(公告)日：2012-01-18
申请号：EP10751504.1
申请日：2010-03-12
发明人： BARBOZA, Mariana , GERMAN, J. Bruce , LEBRILLA, Carlito B. , MILLS, David A. , FREEMAN, Samara , KING, William Robert
IPC分类号： A61K31/702 , A61P1/06 , A61P1/14
摘要： The present invention provides galacto-oligosaccharide compositions that preferentially stimulate growth of specific Bifidobacterium species and subspecies.
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公开(公告)号：EP3369739A1
公开(公告)日：2018-09-05
申请号：EP18167341.9
申请日：2011-07-12
IPC分类号： C07H1/08 , C13K5/00 , C08B37/00 , A61K31/715 , A23C7/00
CPC分类号： A61K31/702 , A23L33/135 , A23L33/28 , A23L33/40 , A23V2002/00 , A61K31/715 , A61K31/726 , A61K35/741 , A61K35/745 , A61K36/062 , C08B37/0003 , C08B37/006 , C08B37/0063 , C08L5/00 , C08L2205/02 , C12P19/14 , C12P19/18 , A23V2200/3202 , A23V2200/3204 , A23V2250/28 , C08L89/00
摘要： Oligosaccharides from bovine milk, whey and dairy products , and methods of producing bovine milk oligosaccharides are provided.
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公开(公告)号：EP2405918B1
公开(公告)日：2014-10-22
申请号：EP10751504.1
申请日：2010-03-12
发明人： BARBOZA, Mariana , GERMAN, J. Bruce , LEBRILLA, Carlito B. , MILLS, David A. , FREEMAN, Samara , KING, William Robert
IPC分类号： A61K31/702 , A61P1/06 , A61P1/14
摘要： The present invention provides galacto-oligosaccharide compositions that preferentially stimulate growth of specific Bifidobacterium species and subspecies.
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公开(公告)号：EP2593466B1
公开(公告)日：2018-05-30
申请号：EP11807372.5
申请日：2011-07-12
IPC分类号： C07H1/08 , C13K5/00 , C08B37/00 , A61K31/715 , A23C7/00
CPC分类号： A61K31/702 , A23L33/135 , A23L33/28 , A23L33/40 , A23V2002/00 , A61K31/715 , A61K31/726 , A61K35/741 , A61K35/745 , A61K36/062 , C08B37/0003 , C08B37/006 , C08B37/0063 , C08L5/00 , C08L2205/02 , C12P19/14 , C12P19/18 , A23V2200/3202 , A23V2200/3204 , A23V2250/28 , C08L89/00
摘要： Oligosaccharides from bovine milk, whey and dairy products , and methods of producing bovine milk oligosaccharides are provided.
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6.发明公开ENZYMES AND METHODS FOR CLEAVING N-GLYCANS FROM GLYCOPROTEINS 审中-公开食品葡萄酒VERFAHREN ZUR SPALTUNG VON N-GLYCANEN AUS GLYCOPROTEINEN
公开(公告)号：EP2814835A1
公开(公告)日：2014-12-24
申请号：EP13748609.8
申请日：2013-02-14
CPC分类号： A61K38/47 , A23C9/1216 , A23L2/52 , A23L33/195 , A61K31/715 , A61K35/741 , A61K38/00 , A61K38/40 , C07K14/79 , C12N9/2402 , C12N9/2497 , C12P19/04 , C12P21/005 , C12Y302/01096 , Y02P20/52 , A61K2300/00
摘要： Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
摘要翻译： 本文提供了去糖基化酶，其从N-糖基化蛋白质中除去宽范围的N-聚糖。 进一步提供重组产生和表达去糖基化酶的方法。 目前描述的去糖基化酶可用于产生游离聚糖用于表征，以及用于益生元和免疫刺激用途。 此外，目前描述的去糖基化酶可用于产生去糖基化蛋白质进行表征，以改善消化并降低免疫原性。
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公开(公告)号：EP3980024A1
公开(公告)日：2022-04-13
申请号：EP20817695.8
申请日：2020-06-02
发明人： LEBRILLA, Carlito B. , GERMAN, Bruce , AMICUCCI, Matthew J. , NANDITA, Eshani , CASTILLO, Juan , MILLS, David A.
IPC分类号： A61K31/702 , A61K31/715 , C12N9/24
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公开(公告)号：EP2405918B2
公开(公告)日：2020-09-02
申请号：EP10751504.1
申请日：2010-03-12
发明人： BARBOZA, Mariana , GERMAN, J. Bruce , LEBRILLA, Carlito B. , MILLS, David A. , FREEMAN, Samara , KING, William Robert
IPC分类号： A61K31/702 , A61P1/06 , A61P1/14
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公开(公告)号：EP3502123A1
公开(公告)日：2019-06-26
申请号：EP19151657.4
申请日：2013-02-14
摘要： Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
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公开(公告)号：EP2593466A2
公开(公告)日：2013-05-22
申请号：EP11807372.5
申请日：2011-07-12
IPC分类号： C07H1/08 , C13K5/00 , C08B37/00 , A61K31/715 , A23C7/00
CPC分类号： A61K31/702 , A23L33/135 , A23L33/28 , A23L33/40 , A23V2002/00 , A61K31/715 , A61K31/726 , A61K35/741 , A61K35/745 , A61K36/062 , C08B37/0003 , C08B37/006 , C08B37/0063 , C08L5/00 , C08L2205/02 , C12P19/14 , C12P19/18 , A23V2200/3202 , A23V2200/3204 , A23V2250/28 , C08L89/00
摘要： Oligosaccharides from bovine milk, whey and dairy products, and methods of producing bovine milk oligosaccharides are provided.
摘要翻译： 提供了来自牛奶，乳清和乳制品的寡糖，以及生产牛乳寡糖的方法。
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