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    POLYBACTERIAL PREPARATION and method for obtaining thereof
    6.
    发明授权
    POLYBACTERIAL PREPARATION and method for obtaining thereof 有权

    公开(公告)号：EP2704733B1

    公开(公告)日：2018-06-20

    申请号：EP12727221.9

    申请日：2012-05-03

    申请人： LB Bulgaricum PLC

    发明人： DIMITROV, Zhechko ,  MICHAYLOVA, Michaela

    IPC分类号： A61K35/747 ,  A23L33/135 ,  C12R1/25 ,  C12R1/225

    CPC分类号： C12R1/25 ,  A23L33/135 ,  A23V2002/00 ,  A23Y2220/37 ,  A23Y2220/39 ,  A23Y2220/67 ,  A61K35/747 ,  C12R1/225 ,  A23V2200/3204 ,  A23V2200/324 ,  A23V2200/3262

    摘要： This invention relates to polybacterial probiotic preparation, which includes new strains of lactic acid bacteria Lactobacillus gasseri 7/12 NBIMCC No. 8720, Lactobacillus plantarum F12 NBIMCC No 8722 and Lactobacillus helveticus A1, NBIMCC No 8721 and has the following set of properties: antioxidant, hypocholesterolemic effect, anti-inflammatory immunomodulating effect, ability to release bioactive peptides that inhibit angiotensin-converting enzyme (ACE), which is responsible for the high blood pressure. The object of invention is also the described probiotic strains of lactic acid bacteria and the developed bacterial products with useful properties. The incorporated probiotic strain Lactobacillus gasseri 7/12 NBIMCC No. 8720, has a number of properties: strong adhesion to the epithelial layer of the colon, the ability for reduction of cholesterol and anti-inflammatory effects by reducing the levels of proinflammatory cytokine interleukin-8. The invention relates to the use of strains of lactic acid bacteria and bacterial agents in the production of starter cultures, food additives, food, functional products and pharmaceutical preparations intended to influence the health of humans and animals.

    HEALTH PRODUCTS WITH INACTIVATED PROBIOTICS AND THEIR USES
    9.
    发明公开
    HEALTH PRODUCTS WITH INACTIVATED PROBIOTICS AND THEIR USES 审中-公开
    具有无效益生菌及其用途的保健产品

    公开(公告)号：EP3289888A1

    公开(公告)日：2018-03-07

    申请号：EP17382031.7

    申请日：2017-01-24

    申请人： De La Fuente Blasco, Pedro Jose

    发明人： De La Fuente Blasco, Pedro Jose

    IPC分类号： A23L33/135 ,  A61K35/741 ,  A61K8/99

    CPC分类号： A23L33/135 ,  A23V2002/00 ,  A61K8/99 ,  A61K35/741 ,  A23V2200/3204 ,  A23V2250/206

    摘要： Health products do not meet the conditions in order for common probiotics to be preserved since they have a degree of moisture greater than 5% and/or a temperature greater than 5°C in any of the processes of production, storage and preservation and into which the inactivated probiotics have been incorporated. The inactivation of the probiotics is achieved by means of subjecting the probiotic strains to high temperatures (range 50°C to 140°C) for a time period of between 30 seconds and 90 minutes depending on the time of exposure of the bacteria to temperatures, in various consecutive sessions and with subsequent cooling to the optimal survival temperature of the bacteria. The use of inactivated probiotics allows them to be incorporated in health forms of different sectors such as: nutraceuticals, dietetics, pharmaceuticals, cosmetics and foodstuffs itself; these probiotics do not require strict temperature and moisture control.

    摘要翻译： 由于健康产品在生产，储存和保存的任何过程中具有大于5％的湿度和/或大于5℃的温度，因此不符合条件以保存普通益生菌， 灭活的益生菌已被纳入。 根据细菌暴露于温度下的时间，通过使益生菌菌株经受高温（范围50℃至140℃）持续30秒至90分钟的时间段来实现益生菌的灭活， 在各种连续的过程中并随后冷却至细菌的最佳存活温度。 灭活益生菌的使用使它们能够被纳入不同部门的健康形式，如：营养品，营养食品，药品，化妆品和食品本身; 这些益生菌不需要严格的温度和湿度控制。