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公开(公告)号：EP3289083A1
公开(公告)日：2018-03-07
申请号：EP16787068.2
申请日：2016-04-27
申请人： The Trustees of The University of Pennsylvania , Acuitas Therapeutics Inc. , Tam, Ying , Hope, Michael J.
发明人： TAM, Ying , HOPE, Michael, J. , WEISSMAN, Drew , PARDI, Norbert
IPC分类号： C12N15/11 , A61K31/7115 , A61K31/712 , A61K9/127 , C07D295/13 , C07C219/08
CPC分类号： A61K39/12 , A61K9/0019 , A61K9/127 , A61K31/7115 , A61K31/712 , A61K39/0011 , A61K39/002 , A61K39/02 , A61K2039/51 , A61K2039/55555 , A61P31/16 , A61P31/18 , A61P35/00 , C07C219/08 , C07D295/13 , C12N15/11
摘要： The present invention relates to compositions and methods for inducing an adaptive immune response in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof.
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公开(公告)号：EP3532097A1
公开(公告)日：2019-09-04
申请号：EP17808636.9
申请日：2017-10-27
发明人： WEISSMAN, Drew , PARDI, Norbert , TAM, Ying , HOPE, Michael, J.
IPC分类号： A61K39/145 , A61K39/21 , A61K39/39 , A61K9/51 , A61K47/18
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公开(公告)号：EP3551169A1
公开(公告)日：2019-10-16
申请号：EP17879571.2
申请日：2017-12-08
发明人： ANSELL, Steven, M. , BARBOSA, Christohper , CONWAY, Anthony , DU, Xinyao , HOPE, Michael, J. , HOLMES, Michael, C. , LEE, Gary, K. , LIN, Paulo, Jia Ching , MADDEN, Thomas , MUI, Barbara
IPC分类号： A61K9/127 , A61K9/51 , A61K31/7088 , A61K31/7105 , A61K35/28 , A61K38/48
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公开(公告)号：EP3532103A1
公开(公告)日：2019-09-04
申请号：EP17800986.6
申请日：2017-10-26
发明人： HOPE, Michael, J. , MUI, Barbara , LIN, Paulo, Jia Ching , BARBOSA, Christopher , MADDEN, Thomas , ANSELL, Steven, M. , DU, Xinyao
IPC分类号： A61K47/18 , A61K47/22 , A61K9/127 , A61K31/7105
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