公开(公告)号：EP3057693A1

公开(公告)日：2016-08-24

申请号：EP14853947.1

申请日：2014-10-16

申请人： The University of British Columbia

发明人： WALSH, Colin ,  WILD, Andre ,  TAYLOR, Robert, James ,  LEAVER, Timothy ,  OU, Kevin ,  RAMSAY, Euan ,  ANSARI, Aysha

IPC分类号： B01F3/08 ,  B01F5/02 ,  F16K11/02

CPC分类号： A61K9/5192 ,  A61K9/5123 ,  A61K31/7105 ,  B01F3/08 ,  B01F3/0807 ,  B01F3/0811 ,  B01F3/0861 ,  B01F5/02 ,  B01F13/0062 ,  B01F13/1022 ,  B01F2215/0032 ,  B01J2/06

摘要： Methods and devices for making particles at small volumes.

摘要翻译： 方法和在小体积使颗粒的设备。

公开(公告)号：EP3262424A1

公开(公告)日：2018-01-03

申请号：EP16756307.1

申请日：2016-02-24

申请人： The University of British Columbia

发明人： RAMSAY, Euan ,  TAYLOR, Robert James ,  LEAVER, Timothy ,  WILD, Andre ,  OU, Kevin ,  WALSH, Colin

IPC分类号： G01N35/08 ,  G01N35/10

CPC分类号： B01F5/0619 ,  A61K9/1682 ,  B01F5/0644 ,  B01F5/0647 ,  B01F13/0059 ,  B01F13/1022 ,  B01F2005/0623 ,  B01F2005/0636 ,  B01F2215/0032 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00824 ,  B01J2219/00831 ,  B01J2219/00833 ,  B01J2219/00855 ,  B01J2219/00858 ,  B01J2219/0086 ,  B01J2219/00869 ,  B01J2219/00873 ,  B01J2219/00889 ,  B01J2219/00894 ,  B01J2219/00898 ,  B01J2219/00986 ,  G01N2015/0038 ,  G01N2035/00158

摘要： The present disclosure is directed towards improved systems and methods for large-scale production of nanoparticles used for delivery of therapeutic material. The apparatus can be used to manufacture a wide array of nanoparticles containing therapeutic material including, but not limited to, lipid nanoparticles and polymer nanoparticles. In certain embodiments, continuous flow operation and parallelization of microfluidic mixers contribute to increased nanoparticle production volume.

公开(公告)号：EP3288671A1

公开(公告)日：2018-03-07

申请号：EP16787188.8

申请日：2016-04-28

申请人： The University of British Columbia

发明人： WILD, Andre ,  LEAVER, Timothy ,  WALSH, Colin ,  HEUCK, Gesine ,  THOMAS, Anitha ,  ANSARI, Aysha ,  OU, Kevin ,  TAYLOR, R., James ,  RAMSAY, Euan

IPC分类号： B01F3/08 ,  B01F5/00 ,  B81B1/00 ,  B82Y40/00

CPC分类号： B82Y40/00 ,  B01F5/061 ,  B01F5/0644 ,  B01F5/0647 ,  B01F13/0059 ,  B01F13/0064 ,  B01F2005/0636 ,  B01L9/527 ,  B01L2200/025 ,  B01L2300/0816 ,  B81B1/00

摘要： The present disclosure is directed towards a disposable microfluidic cartridge configured for use in a system for the small scale production of nanoparticles used in scientific research or therapeutic applications. The system can be used to produce a wide variety of nanoparticles, including but not limited to lipid and polymer nanoparticles, carrying a variety of payloads. The system provides for a simple workflow which in certain embodiments can be used to produce a sterile product.