LIPID NANOPARTICLES FOR TRANSFECTION AND RELATED METHODS
    1.
    发明公开
    LIPID NANOPARTICLES FOR TRANSFECTION AND RELATED METHODS 审中-公开
    LIPIDNANOPARTIKEL ZUR TRANSFKTION UNDZUGEHÖRIGEVERFAHREN

    公开(公告)号:EP2971013A1

    公开(公告)日:2016-01-20

    申请号:EP14785963.1

    申请日:2014-03-14

    IPC分类号: C12N15/88

    摘要: Transfection reagent composition, lipid nanoparticles prepared from the transfection reagent composition, kits that include the transfection reagent composition, and methods for making and using lipid nanoparticles prepared from the transfection reagent composition. Lipids when dispersed in aqueous media readily form liposomes, such as unilamellar vesicles and multilamellar vesicles. Liposomes have been used successfully to encapsulate and deliver a wide range of chemicals including nucleic acids, proteins and, small molecule drugs, to cells.

    摘要翻译: 转染试剂组合物,由转染试剂组合物制备的脂质纳米颗粒,包括转染试剂组合物的试剂盒,以及由转染试剂组合物制备和使用脂质纳米颗粒的方法。 分散在水介质中的脂质容易形成脂质体,如单层囊泡和多层囊泡。 脂质体已被成功地用于包封和递送广泛的化学物质,包括核酸,蛋白质和。 小分子药物,细胞。