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公开(公告)号:EP4365293A1
公开(公告)日:2024-05-08
申请号:EP22833288.8
申请日:2022-06-30
申请人: The University of Tokyo , National University Corporation Nara Institute of Science and Technology
IPC分类号: C12N15/13 , A61K9/19 , A61K39/395 , A61K48/00 , A61P1/04 , A61P3/04 , A61P11/06 , A61P29/00 , A61P31/04 , A61P37/06 , A61P37/08 , C07K16/12 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N5/20 , C12N15/63 , C12P21/08
CPC分类号: Y02A50/30 , A61K9/19 , A61K39/395 , A61K48/00 , A61P1/04 , A61P3/04 , A61P11/06 , A61P29/00 , A61P31/04 , A61P37/06 , A61P37/08 , C07K16/00 , C07K16/12 , C12N5/163 , C12N5/10 , C12N15/63 , C12N15/80 , C12N15/81 , C12N15/74
摘要: The present invention relates to an antibody binding to an intestinal bacterium, an antigen-binding fragment thereof, and uses thereof. In addition, the present invention discloses a nucleic acid encoding the antibody or the antigen-binding fragment thereof, an expression vector comprising the nucleic acid, a cell comprising the nucleic acid or the expression vector, a pharmaceutical composition comprising the antibody or the antigen-binding fragment thereof, a method for producing the antibody, and a method for treating an inflammatory disease by administering the antibody or the antigen-binding fragment thereof.
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2.
公开(公告)号:EP4364755A1
公开(公告)日:2024-05-08
申请号:EP22833312.6
申请日:2022-06-30
发明人: SHINKURA, Reiko , MORITA, Naoki , TAMANO, Ryutaro
摘要: The present invention relates to a composition comprising a monoclonal antibody binding to Clostridium difficile (C. difficile) for inhibiting a growth of Clostridium difficile (C. difficile), and a use thereof. In addition, the present invention discloses the composition for treating an inflammatory bowel disease, and a use thereof.
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