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公开(公告)号：EP1581121B1
公开(公告)日：2011-05-25
申请号：EP02731176.0
申请日：2002-03-26
发明人： ROBY, Mark , KENNEDY, John , STEVENSON, Richard
IPC分类号： A61B17/04
CPC分类号： A61L17/145 , A61B17/06166
摘要： Sutures formed from one or more filaments are coated with an oil, such as for example, mineral oil or castor oil. The sutures exhibit good durability as reflected by fray resistance.
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公开(公告)号：EP1569562A2
公开(公告)日：2005-09-07
申请号：EP03790296.2
申请日：2003-12-04
发明人： ROBY, Mark
IPC分类号： A61B17/04
CPC分类号： A61L17/105 , A61B17/06166 , A61B2017/06028 , A61L17/145 , A61L31/10 , A61L31/16 , A61L2300/22 , A61L2300/404 , A61L2300/606 , C08L67/04
摘要： Compositions with antimicrobial properties contain a metal salt of a fatty acid mixed a bioabsorbable copolymer. These compositions are useful in forming coatings for surgical articles, including multifilament sutures.
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公开(公告)号：EP1581123B1
公开(公告)日：2010-02-17
申请号：EP03813022.5
申请日：2003-12-05
发明人： ROBY, Mark
IPC分类号： A61B17/04
CPC分类号： C09D167/04 , A61B17/06166 , A61B2017/00893 , C08K5/098 , C08L67/04 , Y10T428/2913 , Y10T428/2938 , Y10T428/2967 , Y10T428/2969 , C08L2666/18
摘要： Compositions with antimicrobial properties contain a fatty acid ester salt mixed with a bioabsorbable copolymer. These compositons are useful in forming coatings for surgical articles, including multifilament sutures.
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公开(公告)号：EP1991240A2
公开(公告)日：2008-11-19
申请号：EP07751966.8
申请日：2007-02-28
IPC分类号： A61K31/74 , A61K31/785
CPC分类号： A61K31/74 , A61K31/085 , A61K31/785 , A61K47/34 , A61K47/55 , A61K47/59 , A61K47/593 , A61K47/60 , A61K47/61 , A61L15/46 , A61L15/64 , A61L17/005 , A61L17/06 , A61L17/145 , A61L27/34 , A61L27/54 , A61L27/58 , A61L29/085 , A61L29/148 , A61L29/16 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/202 , A61L2300/404 , A61L2300/604
摘要： The present disclosure is directed to polymers having hydroxyl containing bioactive agents incorporated into the backbone of the polymer or attached thereto by pendant linkages. Hydroxyl containing bioactive agents which may be attached to these polymers include antimicrobial agents such as triclosan. The polymers may be utilized to form medical devices or coatings for such devices. The hydroxyl containing bioactive agent may be released from the polymer upon hydrolysis of the polymeric backbone or pendant linkage in vivo.
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5.发明公开
公开(公告)号：EP1957089A2
公开(公告)日：2008-08-20
申请号：EP06844891.9
申请日：2006-12-06
发明人： KENNEDY, John , ROBY, Mark , HADBA, Ahmad, R.
IPC分类号： A61K31/74
CPC分类号： C08L71/02 , A61K31/74 , A61L24/0042 , A61L24/043 , C08G65/329 , C08G65/332 , C08L79/00 , C08L79/08 , C08L2666/14
摘要： A synthetic composition is provided which includes an acid-functional polymer having at least one pendant acid group, an amine-functional polymer having at least one pendant amine ςiroup, and a coupling agent. The synthetic composition can be used in human and animal medical applications as an adhesive or sealant.
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公开(公告)号：EP1556428A2
公开(公告)日：2005-07-27
申请号：EP03781384.7
申请日：2003-10-27
发明人： ROBY, Mark
IPC分类号： C08G18/00
CPC分类号： C08G18/7614 , A61L24/0015 , A61L24/0073 , A61L24/046 , A61L2300/00 , C08G18/10 , C08G18/12 , C08G18/4833 , C08G18/7671 , C08G18/771 , C08G18/773 , C08G18/776 , C08G18/7868 , C09J175/04 , Y10S528/904 , C08L75/04 , C08G18/307
摘要： Fast curing surgical adhesives and sealants contain an NCO-terminated hydrophilic urethane prepolymer derived from an aromatic diisocyanate and a polyol. Substantially all the aromatic diisocyanate used to prepare the NCO-terminated hydrophilic urethane prepolymer is in the para form. Optionally, the aromatic diisocyanate is substituted with at least one electron withdrawing group, such as, for example, a fluorine group.
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公开(公告)号：EP1476083B1
公开(公告)日：2011-04-27
申请号：EP03709041.2
申请日：2003-02-06
发明人： ROBY, Mark , KENNEDY, John, J. , LEONARD, Frank
IPC分类号： A61B17/06
CPC分类号： A61B17/06166 , A61B2017/0496
摘要： A fray tester for evaluating fray resistance of surgical sutures is provided, which comprises a first and a second pulley rotatably adapted, in a spaced relation to each other, a tensioning weight, and a reciprocity driver. A suture having a first end portion, a second end portion and an intermediate portion is mounted in the fray tester such that the first end portion is subject to the tensioning weight, the intermediate portion is mounted to the first and second pulleys and defines a wrapped portion, the second end portion being connected to the reciprocating driver to cause the suture to rub against itself at a wrapped portion. The reciprocating driver includes a rotating wheel connected to a motor to for providing the reciprocating movement to the suture to be tested. The tester may further include a revolution counter for-counting and displaying the number of reciprocating cycles at the time the suture breaks or seizes.
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公开(公告)号：EP1556430B1
公开(公告)日：2009-06-24
申请号：EP03779244.7
申请日：2003-10-23
发明人： ROBY, Mark
IPC分类号： C08G18/12 , C08G18/42 , C09J175/06 , A61L24/04
CPC分类号： C08G18/10 , A61L24/046 , C08G18/8029 , C08G2230/00 , C08K5/29 , C09J175/06 , C08L75/04 , C08G18/76 , C08L67/04
摘要： Bioabsorbable adhesive or sealant suitable for use in medical or surgical applications contain three compounds. The first compound is an isocyanate-endcapped absorbable oligomer. The second compound is a trifunctional compound that is also diisocyanate terminated, or end-capped. The third compound is an aromatic diisocyanate.
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公开(公告)号：EP1581123A2
公开(公告)日：2005-10-05
申请号：EP03813022.5
申请日：2003-12-05
发明人： ROBY, Mark
IPC分类号： A61B17/04
CPC分类号： C09D167/04 , A61B17/06166 , A61B2017/00893 , C08K5/098 , C08L67/04 , Y10T428/2913 , Y10T428/2938 , Y10T428/2967 , Y10T428/2969 , C08L2666/18
摘要： Compositions with antimicrobial properties contain a fatty acid ester salt mixed with a bioabsorbable copolymer. These compositons are useful in forming coatings for surgical articles, including multifilament sutures.
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公开(公告)号：EP1581121A2
公开(公告)日：2005-10-05
申请号：EP02731176.0
申请日：2002-03-26
发明人： ROBY, Mark , KENNEDY, John , STEVENSON, Richard
IPC分类号： A61B17/04
CPC分类号： A61L17/145 , A61B17/06166
摘要： Sutures formed from one or more filaments are coated with an oil, such as for example, mineral oil or castor oil. The sutures exhibit good durability as reflected by fray resistance.
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