摘要:
Antitoxic fibers and fibrous media contain impregnated material including an antitoxin. A method for producing antitoxic fibers and fibrous media includes impregnating a fibrous media by dipping in a dipping solution containing a concentrate of an antitoxin to form a fiber with impregnated material including an antitoxin. The impregnated material is at least about 1.0% to about 2.5% by weight of the fibers and includes additive chemical components including at least one of an anionic, cationic or nonionic component, an oil and/or an organic solvent, and an alcohol. The additives include those found in a spin finish. The antitoxin is in an amount of at least 0.1% by weight of the fiber. The manufacturing process can be applied to any woven or nonwoven media. Products with antitoxic properties formed therefrom include wound dressings, gowns, articles of clothing, surgical drapes, protective clothing, shoe covers, gloves, hair covers, air filters, including facemasks, privacy, hygienic products, curtains, medical tape, and wipes.
摘要:
A medical dressing (30) is disclosed, comprising an adhesive layer (3) having a skin-facing surface (6) to adhere the medical dressing to a dermal surface, wherein said adhesive layer comprises a first chemical compound incorporated within said adhesive layer, and wherein at least a portion of said skin-facing surface comprises a coating (9) comprising a second chemical compound. Also disclosed is a method of manufacturing such a medical dressing.
摘要:
Antitoxic fibers and fibrous media contain impregnated material including an antitoxin. A method for producing antitoxic fibers and fibrous media includes impregnating a fibrous media by dipping in a dipping solution containing a concentrate of an antitoxin to form a fiber with impregnated material including an antitoxin. The impregnated material is at least about 1.0% to about 2.5% by weight of the fibers and includes additive chemical components including at least one of an anionic, cationic or nonionic component, an oil and/or an organic solvent, and an alcohol. The additives include those found in a spin finish. The antitoxin is in an amount of at least 0.1% by weight of the fiber. The manufacturing process can be applied to any woven or nonwoven media. Products with antitoxic properties formed therefrom include wound dressings, gowns, articles of clothing, surgical drapes, protective clothing, shoe covers, gloves, hair covers, air filters, including facemasks, privacy, hygienic products, curtains, medical tape, and wipes.
摘要:
The invention relates to an antibacterial agent comprising, as active product, a haemostatic contact tissue with an acid pH combined with povidone iodine, the haemostatic contact tissue being regenerated or non-regenerated oxidized cellulose. It also relates to a device used for active protection of incision margins and incorporating such an antibacterial agent. The applicant has now demonstrated surprisingly that the combination of regenerated or non-regenerated oxidized cellulose with povidone iodine provided a degree of bacterial inhibition superior to simple use of regenerated or non-regenerated oxidized cellulose on its own or of povidone iodine on its own. This therefore represents a synergistic effect, which yields a novel agent that is both a very powerful haemostatic and also very powerful antibacterial substance.
摘要:
The present invention provides methods of coating or impregnating medical devices with an antiseptic composition that will inhibit or prevent the nosocomial infections typically associated with the use of such medical devices. The present invention further provides methods of coating or impregnating medical devices that produce devices with effective activity against infection, while avoiding destroying the devices or causing the devices to become toxic. In addition, the invention provides medical devices coated or impregnated with antiseptic compositions by the aforementioned novel methods.
摘要:
Antimicrobial medical devices are prepared with a complexed antimicrobial agent which enhances the adherence of the antimicrobial agent to the medical device.
摘要:
The present disclosure is directed to polymers having hydroxyl containing bioactive agents incorporated into the backbone of the polymer or attached thereto by pendant linkages. Hydroxyl containing bioactive agents which may be attached to these polymers include antimicrobial agents such as triclosan. The polymers may be utilized to form medical devices or coatings for such devices. The hydroxyl containing bioactive agent may be released from the polymer upon hydrolysis of the polymeric backbone or pendant linkage in vivo.
摘要:
An antimicrobial suture assembly comprising a containment compartment comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonization on said containment compartment; and a suture positioned within the containment compartment, the suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonization on the suture; a method for making the antimicrobial suture assembly; and a braided suture having antimicrobial properties comprising an elongate braided structure formed from a plurality of polymeric filaments, said filaments being formed from a polymeric material that is absorbable under physiological conditions, and a coating material disposed on said elongate braided structure, said coating comprising a film forming absorbable polymer, a substantially water-insoluble salt of a fatty acid and an effective amount of an antimicrobial agent selected from the group consisting of halogenated hydroxyl ethers, halogen-o-hydroxy-Biphenyl ethers, acyloxydiphenyl ethers and combinations thereof, said effective amount being sufficient to substantially inhibit microbial growth on or adjacent said suture when said suture is implanted in a patient's body.