公开(公告)号：EP1556001A2

公开(公告)日：2005-07-27

申请号：EP03778010.3

申请日：2003-10-31

申请人： UMD, Inc.

发明人： PAULETTI, Giovanni, M. ,  DESAI, Kishorkumar, J. ,  ROWETON, Susan, L. ,  HARRISON, Donald, C. ,  SANDERS, Lynda, M.

IPC分类号： A61K9/00

CPC分类号： A61K45/06 ,  A61K9/0034 ,  A61K9/0043 ,  A61K9/006 ,  A61K9/02 ,  A61K9/12 ,  A61K9/7007 ,  A61K31/192 ,  A61K31/196 ,  A61K31/277 ,  A61K31/337 ,  A61K31/405 ,  A61K31/407 ,  A61K31/5415 ,  A61K31/616 ,  A61K31/663 ,  A61K38/00 ,  A61L15/425 ,  A61L15/44 ,  A61L26/0066 ,  A61L26/0085 ,  A61L2300/41

摘要： Polymer foams and films for delivery of therapeutic agents to and through nasal, oral or vaginal mucosa and cornified or non-cornified epithelium of labia and scrotum. Polymer foams or absorbable or non-absorbable films containing a therapeutic agent incorporated therein wherein said agent is released from said foams or films upon placement of said foam or film on the surface epithelium of nasal, oral, or vaginal labia or scrotum. The foam or the film has a controllable rate of gelling, swelling and degradation and is preformed into a device or is applied as a coating to a surface of a more complex drug delivery system.

公开(公告)号：EP0988009A1

公开(公告)日：2000-03-29

申请号：EP98924918.0

申请日：1998-06-10

申请人： UMD, Inc.

发明人： HARRISON, Donald, C. ,  LIU, James, H. ,  RITSCHEL, Wolfgang, A. ,  STERN, Roger, A.

IPC分类号： A61F6/06 ,  A61F13/02 ,  A61K9/20

CPC分类号： A61K9/0034 ,  A61F6/08 ,  A61K9/0036

摘要： Methods, devices, and compositions for treatment of dysmenorrhea comprise an intravaginal drug delivery system containing an appropriate pharmaceutical agent incorporated into a pharmaceutically acceptable carrier whereby the pharmaceutical agent is released into the vagina and absorbed through the vaginal mucosa to provide relief of dysmenorrhea. The drug delivery system can be a tampon device (42), vaginal ring, pessary, tablet, suppository, vaginal sponge, bioadhesive tablet, bioadhesive microparticle, cream lotion, foam, ointment, paste solution, or gel. The system delivers a higher concentration to the muscle of the uterus, the primary site for the dyskinetic muscle contraction, which is the pathophysiologic cause of dysmenorrhea.

公开(公告)号：EP1311213A1

公开(公告)日：2003-05-21

申请号：EP01957150.4

申请日：2001-07-12

申请人： UMD, Inc.

发明人： HARRISON, Donald, C. ,  LIU, James, H.

IPC分类号： A61F13/00 ,  A61F6/06 ,  A61F13/02

CPC分类号： A61K9/0036 ,  A61F6/08 ,  A61K9/0034 ,  A61K9/02

摘要： Devices, methods, and compositions for vaginal delivery of bisphosphonates. A targeted site delivery of bisphosphonates to the vagina using a medicated intravaginal device comprising a bisphosphonate composition formulated for transvaginal delivery. A method for treatment of osteoporosis and related bone and skeleton diseases, for prevention of bone breakdown and loss of bone mass and strength by intravaginal administration of bisphosphonates to the vagina and transvaginal delivery of bisphosphonates to the general circulation.

公开(公告)号：EP1301150A1

公开(公告)日：2003-04-16

申请号：EP01959766.5

申请日：2001-06-25

申请人： UMD, Inc.

发明人： D'AUGUSTINE, Merida, A. ,  LIU, James, H. ,  HARRISON, Donald, C.

IPC分类号： A61F6/06 ,  A61F13/02 ,  A61F13/00 ,  A61L15/16

CPC分类号： A61F6/08 ,  A61F13/2051 ,  A61K9/0034 ,  A61K9/0036

摘要： Devices, methods, and compositions for treating vaginal fungal, bacterial, viral and parasitic infections by intravaginal or transvaginal administration of therapeutic and/or palliative antifungal, antibacterial, antiviral or parasiticidal drugs to the vagina or to the uterus.