公开(公告)号：EP0763009A4

公开(公告)日：1998-05-06

申请号：EP95921230

申请日：1995-05-11

申请人： UNIV BOSTON

发明人： ROTHSCHILD KENNETH J ,  SONAR SANJAY M ,  OLEJNIK JERZY

IPC分类号： A61K38/00 ,  A61K41/00 ,  C07C205/45 ,  C07C205/57 ,  C07D207/40 ,  C07D207/404 ,  C07D311/16 ,  C07D405/12 ,  C07D495/04 ,  C07H19/04 ,  C07H21/00 ,  C07K1/107 ,  C07K1/13 ,  C12P21/00 ,  G01N33/532 ,  C07C205/00 ,  C07C205/06 ,  C07C205/07 ,  C07D235/02 ,  C07H1/06 ,  C07H1/08

CPC分类号： C12Q1/6876 ,  A61K38/00 ,  A61K41/0042 ,  C07C205/45 ,  C07C205/57 ,  C07D207/404 ,  C07D311/16 ,  C07D405/12 ,  C07D495/04 ,  C07H19/04 ,  C07H21/00 ,  C07K1/1077 ,  C07K1/13 ,  C12P21/00 ,  G01N33/532

摘要： The present invention relates to a bioreactive agent comprising a detectable moiety linked to a photo-reactive moiety, wherein said photoreactive moiety comprises at least one group covalently bound to a substrate to form a conjugate that can be selectively photocleaved to release said substrate, wherein said substrate is selected from proteins, peptides, amino acids, lipids, cells, virus particles, fatty acids, nucleic acids, nucleotides, nucleosides, oligonucleotides, polysaccharides and inorganic molecules.