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    ULTRA LOW STRENGTH ELECTRIC FIELD NETWORK-MEDIATED EX VIVO GENE, PROTEIN AND DRUG DELIVERY IN CELLS
    1.
    发明公开
    ULTRA LOW STRENGTH ELECTRIC FIELD NETWORK-MEDIATED EX VIVO GENE, PROTEIN AND DRUG DELIVERY IN CELLS 审中-公开
    ULTRA低电场网络介导的体外基因，蛋白质和药物供给细胞

    公开(公告)号：EP1865969A4

    公开(公告)日：2009-07-15

    申请号：EP06739868

    申请日：2006-03-16

    申请人： UNIV CALIFORNIA

    发明人： SEN LUYI ,  GUANGGEN CUI

    IPC分类号： A61K31/711 ,  C12N15/64

    CPC分类号： C12N15/87 ,  C12M35/02

    摘要： Ex vivo gene, protein or drug delivery to macroscopic quantities of various types of cells, cell clusters, or tissues using ultra low strength LSEFN strategies is disclosed in which the bioengineered cells and tissues are then systemically transfused, delivered or implanted into the various organs or tissue for the treatment of diseases. An LSEFN chamber is used which is shaped and sized to intimately contain the cells, cell clusters, or tissues in a transfusion chamber between opposing membrane encapsulated electrode arrays across which LSEFN pulses are applied.