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公开(公告)号:EP0774971A4
公开(公告)日:1998-06-10
申请号:EP94919201
申请日:1994-06-07
申请人: UNIV DUKE
发明人: BOLOGNESI DANI P , MATTHEWS THOMAS J , WILD CARL T , BARNEY SHAEN O'LIN , LAMBERT DENNIS M , PETTEWAY STEPHEN R JR
IPC分类号: G01N33/566 , A61K38/00 , A61K38/16 , A61K39/00 , A61K39/12 , A61P31/12 , C07K5/083 , C07K5/087 , C07K5/09 , C07K5/093 , C07K5/103 , C07K5/107 , C07K5/113 , C07K5/117 , C07K7/06 , C07K7/08 , C07K14/005 , C07K14/02 , C07K14/05 , C07K14/11 , C07K14/115 , C07K14/12 , C07K14/125 , C07K14/13 , C07K14/135 , C07K14/15 , C07K14/155 , C07K14/16 , C07K14/21 , C07K14/22 , C07K14/285 , C07K14/31 , C07K17/08 , C07K17/10 , C12N15/11 , C12N15/62 , C12N15/63 , C12Q1/00 , C12Q1/70 , G01N33/53 , G01N33/569
CPC分类号: C07K14/005 , A61K38/00 , A61K39/00 , A61K2039/525 , C07K5/0806 , C07K5/0808 , C07K5/0812 , C07K5/0815 , C07K5/0817 , C07K5/0819 , C07K5/1008 , C07K5/101 , C07K5/1013 , C07K5/1016 , C07K5/1021 , C07K5/1024 , C07K14/21 , C07K14/22 , C07K14/285 , C07K14/31 , C12N2710/16222 , C12N2730/10122 , C12N2740/15022 , C12N2740/16122 , C12N2740/16222 , C12N2760/16122 , C12N2760/18022 , C12N2760/18122 , C12N2760/18422 , C12N2760/18522 , Y10S435/974 , Y10S530/826
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公开(公告)号:EP0652895A4
公开(公告)日:1997-02-05
申请号:EP93917272
申请日:1993-07-19
申请人: UNIV DUKE
发明人: WILD CARL T , MATTHEWS THOMAS J , BOLOGNESI DANI P
IPC分类号: C12N15/09 , A61K38/00 , A61P31/12 , C07K14/11 , C07K14/135 , C07K14/15 , C07K14/155 , C07K14/16 , C12N5/08 , C07K7/00
CPC分类号: C07K14/005 , A61K38/00 , C12N2740/16122 , C12N2760/16022 , C12N2760/18522 , Y10S530/806
摘要: This invention relates to human immunodeficiency virus (HIV) protein fragments which have antiviral activity, and particularly relates to HIV peptides derived from the HIV transmembrane glycoprotein (gp41) which inhibit HIV-induced cell-cell fusion. This invention further relates to methods for the inhibition of enveloped viral infection, and to methods that modulate biochemical processes which involve coiled coil peptide interactions.
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