BIOMIMETIC MICROFLUID DEVICE FOR CAPTURING CIRCULATING TUMOR CELLS
    2.
    发明公开
    BIOMIMETIC MICROFLUID DEVICE FOR CAPTURING CIRCULATING TUMOR CELLS 审中-公开
    BIOMIMETISCHE MIKROFLUIDVORRICHTUNG ZUR ERFASSUNG VON ZIRKULIERENDEN TUMORZELLEN

    公开(公告)号:EP3114484A4

    公开(公告)日:2017-08-30

    申请号:EP15759126

    申请日:2015-03-09

    申请人: UNIV ILLINOIS

    IPC分类号: G01N33/574

    摘要: A method of capturing a Circulating Tumor Cell (CTC) and Circulating Cancer Cells (CSC) from a sample includes introducing a sample into a flow based multichannel device having a cell capture surface and a flow modification surface under conditions that allow a CTC to bind to a cell rolling-inducing agent and a capturing agent disposed on the cell capture surface. The invention also provides for flow based multichannel devices to capture CTCs and CSCs from a sample.

    摘要翻译: 从样品中捕获循环肿瘤细胞(CTC)和循环癌细胞(CSC)的方法包括将样品引入基于流动的多通道装置中,所述多通道装置具有细胞捕获表面和流动修饰表面,所述条件允许CTC结合 细胞卷动诱导剂和设置在细胞捕获表面上的捕获剂。 本发明还提供了基于流的多通道设备来捕获样品中的CTC和CSC。