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1.发明公开METHODS AND SYSTEMS FOR ANALYSIS OF SINGLE CELLS 有权VERFAHREN UND SYSTEME ZUR ANALYZE VON EINZELZELLEN
公开(公告)号：EP2596006A4
公开(公告)日：2014-04-16
申请号：EP11810302
申请日：2011-07-19
发明人： CLARKE MICHAEL F , QUAKE STEPHEN R , DALERBA PIERO D , LIU HUIPING , LEYRAT ANNE , KALISKY TOMER , DIEHN MAXIMILIAN , ROTHENBERG MICHAEL , WANG JIANBIN , LOBO NEETHAN
CPC分类号： C12N15/1072 , C12Q1/6809 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158
摘要： Methods are provided for diagnosis and prognosis of disease by analyzing expression of a set of genes obtained from single cell analysis. Classification allows optimization of treatment, and determination of whether on whether to proceed with a specific therapy, and how to optimize dose, choice of treatment, and the like. Single cell analysis also provides for the identification and development of therapies which target mutations and/or pathways in disease-state cells.
摘要翻译： 通过分析从单细胞分析获得的一组基因的表达，为疾病的诊断和预后提供方法。 分类允许优化治疗，确定是否进行特定治疗，以及如何优化剂量，治疗选择等。 单细胞分析还提供了鉴定和开发针对疾病状态细胞中的突变和/或途径的疗法。
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2.发明公开SINGLE CELL GENE EXPRESSION FOR DIAGNOSIS, PROGNOSIS AND IDENTIFICATION OF DRUG TARGETS 有权单细胞基因表达诊断，预后和ACTIVE目标识别
公开(公告)号：EP2389453A4
公开(公告)日：2012-10-03
申请号：EP10733816
申请日：2010-01-20
发明人： CLARKE MICHAEL F , QUAKE STEPHEN R , DALERBA PIERO D , LIU HUIPING , LEYRAT ANNE , KALISKY TOMER , DIEHN MAXIMILLIAN , WANG JIANBIN
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , C12Q2600/178 , G01N33/5023 , G01N33/57484 , G01N2800/52
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