公开(公告)号：EP2170429A2

公开(公告)日：2010-04-07

申请号：EP08762515.8

申请日：2008-06-25

申请人： UNIVERSITY COLLEGE LONDON

发明人： SELDEN, Clare ,  HODGSON, Humphrey ,  COWARD, Sam

IPC分类号： A61M1/36 ,  A61M1/34

CPC分类号： A01N1/0247 ,  A01N1/02 ,  A01N1/0257 ,  A61F2/022 ,  A61M1/3472 ,  A61M1/3489 ,  A61M1/3689 ,  C12M21/08 ,  C12M23/06 ,  C12M25/16 ,  C12M29/04 ,  C12M41/24 ,  C12N5/0671 ,  C12N2511/00 ,  C12N2533/12 ,  C12N2533/74

摘要： The present invention relates to the field of extracorporeal liver perfusion and, more particularly, to a method of proliferating human hepatocyte derived cells. It comprises; a) Seeding cells into a matrix forming agent; b) Pre-culturing the matrix encapsulated cells so that they form cohesive spheroids and; c) Growing them to performance competence.

公开(公告)号：EP2170429B1

公开(公告)日：2013-08-14

申请号：EP08762515.8

申请日：2008-06-25

申请人： UNIVERSITY COLLEGE LONDON

发明人： SELDEN, Clare ,  HODGSON, Humphrey ,  COWARD, Sam

IPC分类号： A61M1/36 ,  A61M1/34 ,  A01N1/02 ,  C12M1/00

CPC分类号： A01N1/0247 ,  A01N1/02 ,  A01N1/0257 ,  A61F2/022 ,  A61M1/3472 ,  A61M1/3489 ,  A61M1/3689 ,  C12M21/08 ,  C12M23/06 ,  C12M25/16 ,  C12M29/04 ,  C12M41/24 ,  C12N5/0671 ,  C12N2511/00 ,  C12N2533/12 ,  C12N2533/74

摘要： The present invention relates to the field of extracorporeal liver perfusion and, more particularly, to a method of proliferating human hepatocyte derived cells. It comprises; a) Seeding cells into a matrix forming agent; b) Pre-culturing the matrix encapsulated cells so that they form cohesive spheroids and; c) Growing them to performance competence.