公开(公告)号：EP1004042A2

公开(公告)日：2000-05-31

申请号：EP98936831.1

申请日：1998-07-09

申请人： UNIVERSITY OF SOUTH CAROLINA

发明人： MYRICK, Michael, L. ,  NELSON, Mathew, P. ,  BOOKSH, Karl, S.

IPC分类号： G02B1/00

CPC分类号： G01N21/274 ,  G01J3/28 ,  G01N21/31 ,  G01N2021/3196

摘要： An optical analysis system (44) includes an optical filter mechanism (52) disposed to receive light from a light source (46) and configured to optically compress data carried by the light into at least one orthogonal component of the light. A detector (56) mechanism in operative communication with the optical filter mechanism measures a property of the at least one orthogonal component to measure the data.

公开(公告)号：EP1004042B1

公开(公告)日：2009-08-26

申请号：EP98936831.1

申请日：1998-07-09

申请人： UNIVERSITY OF SOUTH CAROLINA

发明人： MYRICK, Michael, L. ,  NELSON, Mathew, P. ,  BOOKSH, Karl, S.

IPC分类号： G02B1/00 ,  G01J3/12 ,  G01J3/28

CPC分类号： G01N21/274 ,  G01J3/28 ,  G01N21/31 ,  G01N2021/3196

摘要： An optical analysis system includes an optical filter mechanism disposed to receive light from a light source and configured to optically compress data carried by the light into at least one orthogonal component of the light. A detector mechanism in operative communication with the optical filter mechanism measures a property of the at least one orthogonal component to measure the data.

公开(公告)号：EP1955046A1

公开(公告)日：2008-08-13

申请号：EP06738057.6

申请日：2006-03-10

申请人： University of South Carolina

发明人： MYRICK, Michael, L. ,  FREESE, Robert, P. ,  PRIORE, Ryan, J. ,  BLACKBURN, John, C. ,  JAMES, Jonathan, H. ,  PERKINS, David L.

IPC分类号： G01N21/31 ,  G01N21/85

CPC分类号： G01N21/4738 ,  G01N21/31 ,  G01N21/9508

摘要： A method of high-speed processing and monitoring of a product, such as a pharmaceutical powder or tablet, comprises: moving the product (C) past an inspection station; illuminating at least a portion of the product with light; spectrally filtering a first portion of light carrying invormation about the product, o.g., transmitted or reflected light, by passing said first portion through at least one multivariate optical element (148) and detecting said filtered light with a first detector (152), - detecting a deflected second portion of said light with a second detector (156); and determining at least one selected property of the product based on the detector outputs.

公开(公告)号：EP1955032A1

公开(公告)日：2008-08-13

申请号：EP06838421.3

申请日：2006-11-27

申请人： University of South Carolina

发明人： PRIORE, Ryan, J. ,  FREESE, Robert, P. ,  MYRICK, Michael, L. ,  BLACKBURN, John, C.

IPC分类号： G01J3/06

CPC分类号： G01J3/28 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0232 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/08 ,  G01N21/274 ,  G01N21/31 ,  G06F17/18 ,  G06F17/50 ,  G06F17/5009 ,  G06F17/5086

摘要： Methods of selecting spectral elements and system components for a multivariate optical analysis system include providing spectral calibration data for a sample of interest; identifying a plurality of combinations of system components; modeling performance of a pilot system with one of the combinations of system components; determining optimal characteristics of the pilot system; and selecting optimal system components from among the combinations of system components.

公开(公告)号：EP1797478A2

公开(公告)日：2007-06-20

申请号：EP05858207.3

申请日：2005-10-04

申请人： UNIVERSITY OF SOUTH CAROLINA

发明人： PERKINS, David, L. ,  MYRICK, Michael, L. ,  PRIORE, Ryan, J.

IPC分类号： G02F3/00

CPC分类号： G01N21/3504 ,  G01N2021/1704

摘要： A method of using photoacoustic spectroscopy to determine chemical information about an analyte includes the steps of emitting a light ray for interaction with a sample of an analyte; transmitting the light ray through a fill fluid disposed in a detection cell, the fill fluid having molecules substantially similar to molecules of the analyte to absorb the light ray; producing a thermal wave and oscillation in the fill fluid proportional to an intensity of the light ray; including a pressure oscillation in the fill fluid by the thermal wave; and detecting the pressure oscillation by a microphone to determine information about the analyte sample

公开(公告)号：EP1977204A1

公开(公告)日：2008-10-08

申请号：EP06838366.0

申请日：2006-11-27

申请人： University of South Carolina

发明人： MYRICK, Michael, L. ,  FREESE, Robert, P. ,  BLACKBURN, John, C. ,  PRIORE, Ryan, J.

IPC分类号： G01J3/36

CPC分类号： G01J3/08 ,  A61K8/046 ,  A61K8/25 ,  A61K8/26 ,  A61K8/44 ,  A61Q11/00 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/021 ,  G01J3/0232 ,  G01J3/0291 ,  G01J3/28 ,  G01N21/274 ,  G01N21/31

摘要： A method of arranging and utilizing a multivariate optical computing and analysis system includes transmitting a first light from a light source; generating a second light by reflecting the first light from the sample; directing a portion of the second light with a beamsplitter; and arranging an optical filter mechanism in a normal incidence orientation to receive the portion of the second light, the optical filter mechanism being configured to optically filter data carried by the portion of the second light.

公开(公告)号：EP1974201A1

公开(公告)日：2008-10-01

申请号：EP06738078.2

申请日：2006-03-10

申请人： University of South Carolina

发明人： MYRICK, Michael, L. ,  FREESE, Robert, P. ,  PRIORE, Ryan, J. ,  BLACKBURN, John, C. ,  JAMES, Jonathan, H. ,  PERKINS, David, L.

IPC分类号： G01N21/31

CPC分类号： G01N21/4738 ,  G01N21/31 ,  G01N21/9508

摘要： A method of real-time processing and monitoring comprises the steps Of blending a material of interest (e.g., an active pharmceutical material), with a secondary material, (e.g., an excipient), illuminating the blended materials with light, reflecting light carrying information about the blended materials through at least one multivariate optical element (148) and detecting said light with a first detector (152), detecting a deflected portion of the information carrying light with a second detector (156), and determining in real-time at least one selected property of the blended materials based on the detector outputs.