公开(公告)号：EP0890094A1

公开(公告)日：1999-01-13

申请号：EP97936008.0

申请日：1997-03-31

申请人： UNIVERSITY OF WASHINGTON

发明人： WEIGL, Bernhard, H. ,  YAGER, Paul ,  BRODY, James, P. ,  HOLL, Mark, R. ,  KENNY, Margaret ,  SCHUTTE, David ,  HIXSON, Gregory ,  ZEBERT, M., Diane ,  KAMHOLZ, Andrew ,  WU, Caicai ,  ALTENDORF, Eric

IPC分类号： G01N37 ,  B01F5 ,  B01F13 ,  B01J19 ,  B01L3 ,  G01N15 ,  G01N30 ,  G01N31 ,  G01N35

CPC分类号： B01F5/0403 ,  B01F13/0059 ,  B01F13/0093 ,  B01J19/0093 ,  B01J2219/00828 ,  B01J2219/00831 ,  B01J2219/00952 ,  B01L3/502776 ,  B01L2200/0636 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0487 ,  G01N15/14 ,  G01N30/0005 ,  G01N30/38 ,  G01N30/6095 ,  G01N30/74 ,  G01N35/085 ,  Y10S366/01 ,  Y10T436/25375 ,  Y10T436/2575

摘要： A channel-cell system is provided for detecting the presence and/or measuring the presence of analyte particles in a sample stream comprising a laminar flow channel (100), two inlet means (30, 20) in fluid connection with said laminar flow channel (100) for respectively conducting into the laminar flow channel (100) an indicator stream (70) which may comprise an indicator substance which indicates the presence of said analyte particles by a detectable change in property when contacted with said analyte particles, and the sample stream (80), wherein the laminar flow channel (100) has a depth sufficiently small to allow laminar flow of the streams and a length sufficient to allow particles of the analyte to diffuse into said indicator stream (70) to the substantial exclusion of said larger particles in the sample stream (80) to form a detection area; and outlet means (60) for conducting the streams out of the laminar flow channel (100) to form a single mixed stream.

公开(公告)号：EP0890094B1

公开(公告)日：2003-09-17

申请号：EP97936008.8

申请日：1997-03-31

申请人： UNIVERSITY OF WASHINGTON

发明人： WEIGL, Bernhard, H. ,  YAGER, Paul ,  BRODY, James, P. ,  HOLL, Mark, R. ,  KENNY, Margaret ,  SCHUTTE, David ,  HIXSON, Gregory ,  ZEBERT, M., Diane ,  KAMHOLZ, Andrew ,  WU, Caicai ,  ALTENDORF, Eric

IPC分类号： G01N21/64 ,  G01N35/08

CPC分类号： B01F5/0403 ,  B01F13/0059 ,  B01F13/0093 ,  B01J19/0093 ,  B01J2219/00828 ,  B01J2219/00831 ,  B01J2219/00952 ,  B01L3/502776 ,  B01L2200/0636 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0487 ,  G01N15/14 ,  G01N30/0005 ,  G01N30/38 ,  G01N30/6095 ,  G01N30/74 ,  G01N35/085 ,  Y10S366/01 ,  Y10T436/25375 ,  Y10T436/2575