公开(公告)号：EP0839318A1

公开(公告)日：1998-05-06

申请号：EP96925261.0

申请日：1996-06-14

申请人： University of Washington

发明人： YAGER, Paul ,  BRODY, James, P. ,  HOLL, Mark, R. ,  FORSTER, Fred, K. ,  GALAMBOS, Paul, C.

IPC分类号： B01D11 ,  B01D43 ,  B01F13 ,  B01J19 ,  G01N1 ,  G01N15 ,  G01N30 ,  G01N37 ,  G01N35

CPC分类号： B01D11/0492 ,  B01D11/0496 ,  B01F13/0059 ,  B01F13/0093 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00828 ,  B01J2219/00889 ,  B01J2219/00905 ,  B01J2219/00952 ,  B01J2219/0097 ,  B01J2219/00995 ,  G01N15/06 ,  G01N30/0005 ,  G01N2001/4072 ,  G01N2035/00237 ,  Y10S366/01 ,  Y10T436/255

摘要： This invention provides a microfabricated extraction system and methods for extracting desired particles from a sample stream containing desired and undesired particles. The sample stream is placed in laminar flow contact with an extraction stream under conditions in which inertial effects are negligible. The contact between the two streams is maintained for a sufficient period of time to allow differential transport of the desired particles from the sample stream into the extraction stream. In a preferred embodiment the differential transport mechanism is diffusion. The extraction system of this invention coupled to a microfabricated diffusion-based mixing device and/or sensing means allows picoliter quantities of fluid to be processed or analyzed on devices no larger than silicon wafers.

公开(公告)号：EP0839318B1

公开(公告)日：2003-05-07

申请号：EP96925261.8

申请日：1996-06-14

申请人： University of Washington

发明人： YAGER, Paul ,  BRODY, James, P. ,  HOLL, Mark, R. ,  FORSTER, Fred, K. ,  GALAMBOS, Paul, C.

IPC分类号： G01N30/00 ,  G01N15/06

CPC分类号： B01D11/0492 ,  B01D11/0496 ,  B01F13/0059 ,  B01F13/0093 ,  B01F2005/0031 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00828 ,  B01J2219/00889 ,  B01J2219/00905 ,  B01J2219/00952 ,  B01J2219/0097 ,  B01J2219/00995 ,  G01N15/06 ,  G01N30/0005 ,  G01N2001/4072 ,  G01N2035/00237 ,  Y10S366/01 ,  Y10T436/255