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公开(公告)号：EP1817032A2
公开(公告)日：2007-08-15
申请号：EP05852296.2
申请日：2005-11-29
发明人： HURLEY, Dennis, J. , BERGERON, Daniele, M. , DRUTU, Ioana , GARCIA-GUZMAN BLANCO, Miguel , MAKINGS, Lewis, R. , NAKATANI, Akiko , RAFFAI, Gabriel , SILINA, Alina
IPC分类号： A61K31/4439 , A61K31/454 , A61P25/18
CPC分类号： C07D211/10 , A61K31/4439 , C07D211/18 , C07D211/32 , C07D211/34 , C07D211/38 , C07D211/42 , C07D211/52 , C07D211/64 , C07D401/04 , C07D401/06 , C07D401/10 , C07D405/04 , C07D405/06 , C07D405/10 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/10 , C07D417/10 , C07D417/12 , C07D451/02 , C07D493/08
摘要： The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
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公开(公告)号：EP1781288A2
公开(公告)日：2007-05-09
申请号：EP05792897.0
申请日：2005-08-19
发明人： MAKINGS, Lewis, R. , GARCIA-GUZMAN BLANCO, Miguel , HURLEY, Dennis, J. , DRUTU, Ioana , RAFFAI, Gabriel , BERGERON, Daniele, M. , NAKATANI, Akiko , TERMIN, Andreas, P. , SILINA, Alina
IPC分类号： A61K31/435 , A61K31/438 , A61P43/00 , A61P25/00 , C07D471/00
CPC分类号： C07D401/06 , A61K31/435 , A61K31/438 , A61K31/4747 , A61K31/55 , C07D221/20 , C07D223/32 , C07D405/04 , C07D405/06 , C07D405/12 , C07D451/02 , C07D451/04 , C07D471/10 , C07D491/10
摘要： The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
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公开(公告)号：EP1973543A2
公开(公告)日：2008-10-01
申请号：EP06848092.0
申请日：2006-12-22
发明人： MAKINGS, Lewis, R. , GARCIA-GUZMAN BLANCO, Miguel , HURLEY, Dennis, J. , DRUTU, Ioana , RAFFAI, Gabriel , BERGERON, Daniele, M. , NAKATANI, Akiko , TERMIN, Andreas, P. , SILINA, Alina
IPC分类号： A61K31/435 , A61K31/438 , A61P43/00 , A61P25/00 , C07D471/00 , A61K31/4545 , A61K31/46 , A61K31/497 , A61K31/498 , A61K31/501 , A61K31/506 , C07D471/10
CPC分类号： A61K31/4545 , A61K31/438 , A61K31/46 , A61K31/497 , A61K31/498 , A61K31/501 , A61K31/506 , C07D221/20 , C07D401/04 , C07D401/06 , C07D405/04 , C07D417/14 , C07D471/10 , C07D487/08 , C07D491/10
摘要： The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
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公开(公告)号：EP1863490A2
公开(公告)日：2007-12-12
申请号：EP06739746.3
申请日：2006-03-28
发明人： DRUTU, Ioana , GARCIA-GUZMAN BLANCO, Miguel , MAKINGS, Lewis, R. , RAFFAI, Gabriel , ZUNIC, Valentin, Boris
IPC分类号： A61K31/46 , A61K31/4468 , A61K31/453 , C07D451/04 , C07D401/04 , C07D211/58 , A61P25/00
CPC分类号： C07D211/58 , A61K31/4468 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/46 , A61K31/4709 , A61K31/497 , A61K31/498 , A61K31/501 , A61K31/502 , A61K31/52 , A61K31/53 , C07D451/04 , C07D519/00
摘要： The present invention relates to modulators of muscarinic receptors formula (I). The present invention also provides compositions comprising such modulators/ and methods therewith for treating muscarinic receptor mediated diseases.
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公开(公告)号：EP1817036B1
公开(公告)日：2012-07-04
申请号：EP05852309.3
申请日：2005-11-29
发明人： DRUTU, Ioana , HURLEY, Dennis, J. , BANDARAGE, Upul, K. , BERGERON, Daniele, M. , CHARIFSON, Paul, S. , DAVIES, Robert, J. , GARCIA-GUZMAN BLANCO, Miguel , MAKINGS, Lewis, R. , NAKATANI, Akiko , RAFFAI, Gabriel
IPC分类号： C07D471/00 , C07D471/08 , C07D491/08 , A61K31/4747 , A61K31/435 , A61K31/4545 , A61K31/439 , A61K31/444 , A61P43/00 , A61P25/00 , A61P27/02 , A61P3/04 , A61P1/00 , A61P17/02 , A61P9/00
CPC分类号： C07D471/10 , A61K31/435 , A61K31/439 , A61K31/444 , A61K31/4545 , A61K31/4747 , C07D471/08 , C07D491/08 , C07D491/10
摘要： The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
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公开(公告)号：EP1673089A2
公开(公告)日：2006-06-28
申请号：EP04789051.2
申请日：2004-09-27
发明人： GARCIA-GUZMAN BLANCO, Miguel , BERGERON, Daniele , GROOTENHUIS, Peter, D., J. , HURLEY, Dennis, James , NAKATANI, Akiko , MAKINGS, Lewis, R. , DISEPIO, Daniel , RAFFAI, Gabriel
IPC分类号： A61K31/495 , A61K31/496 , C07D295/04 , A61P43/00
CPC分类号： C07D295/033 , A61K31/495 , A61K31/496 , C07D211/58 , C07D295/073 , C07D295/096 , C07D295/135 , C07D295/155 , C07D309/14 , C07D451/02 , C07D451/04 , C07D493/08
摘要： The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
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公开(公告)号：EP1987034B1
公开(公告)日：2011-07-20
申请号：EP07751501.3
申请日：2007-02-22
发明人： MAKINGS, Lewis, R. , GARCIA-GUZMAN BLANCO, Miguel , HURLEY, Dennis, J. , DRUTU, Ioana , RAFFAI, Gabriel , BERGERON, Daniele, M. , NAKATANI, Akiko , TERMIN, Andreas, P. , SILINA, Alina
IPC分类号： C07D471/10 , C07D519/00 , A61K31/438 , A61K31/46 , A61K31/4747 , A61P25/00
CPC分类号： C07D471/10
摘要： The present invention relates to modulators of muscarnic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
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公开(公告)号：EP1817036A2
公开(公告)日：2007-08-15
申请号：EP05852309.3
申请日：2005-11-29
发明人： DRUTU, Ioana , HURLEY, Dennis, J. , BANDARAGE, Upul, K. , BERGERON, Daniele, M. , CHARIFSON, Paul, S. , DAVIES, Robert, J. , GARCIA-GUZMAN BLANCO, Miguel , MAKINGS, Lewis, R. , NAKATANI, Akiko , RAFFAI, Gabriel
IPC分类号： A61K31/4747 , A61K31/435 , A61K31/4545 , A61K31/439 , A61K31/444 , C07D471/00 , A61P43/00 , A61P25/00 , A61P27/02 , A61P3/04 , A61P1/00 , A61P17/02 , A61P9/00
CPC分类号： C07D471/10 , A61K31/435 , A61K31/439 , A61K31/444 , A61K31/4545 , A61K31/4747 , C07D471/08 , C07D491/08 , C07D491/10
摘要： The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
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