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公开(公告)号：EP2276879A2
公开(公告)日：2011-01-26
申请号：EP09730154.3
申请日：2009-04-10
申请人： Virginia Commonwealth University , HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
CPC分类号： A61L15/44 , A61F13/00034 , A61F13/00063 , A61F2013/00472 , A61F2013/0054 , A61F2013/00927 , A61L15/28 , A61L15/32 , A61L2300/418 , A61L2400/04 , D01D5/0015 , D01F1/10 , D01F6/92 , D01F9/00 , C08L5/02
摘要： The invention generally relates to dextran fibers which are preferably electrospun and devices formed from such fibers. In particular, such devices may include substances of interest (such as therapeutic substances) associated with the electrospun fibers. Upon exposure to a liquid the electrospun fibers dissolve immediately and the substances of interest are released into the liquid. Exemplary devices include bandages formed from electrospun dextran fibers and associated agents that promote hemostasis, such as thrombin and fibrinogen.
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公开(公告)号：EP2276879B1
公开(公告)日：2015-11-25
申请号：EP09730154.3
申请日：2009-04-10
申请人： Virginia Commonwealth University , HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
CPC分类号： A61L15/44 , A61F13/00034 , A61F13/00063 , A61F2013/00472 , A61F2013/0054 , A61F2013/00927 , A61L15/28 , A61L15/32 , A61L2300/418 , A61L2400/04 , D01D5/0015 , D01F1/10 , D01F6/92 , D01F9/00 , C08L5/02
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公开(公告)号：EP1345743B1
公开(公告)日：2008-07-23
申请号：EP01995191.2
申请日：2001-11-16
发明人： SIMPSON, David, G. , BOWLIN, Gary, L. , WNEK, Gary, E. , STEVENS, Peter, J. , CARR, Marcus, E., Jr. , MATTHEWS, Jamil, A. , RAJENDRAN, Saravanamoorthy
CPC分类号： C12N5/0068 , A61K2035/126 , A61L15/32 , A61L27/24 , A61L27/26 , A61L27/38 , A61L31/041 , A61L2400/04 , B29C41/006 , B29C67/0007 , C07K14/78 , C12N5/0012 , C12N2533/40 , C12N2533/54 , D01D5/0038 , D01F1/10 , D01F4/00 , C08L89/06
摘要： The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
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4.发明授权
公开(公告)号：EP1333808B1
公开(公告)日：2012-07-25
申请号：EP01987661.4
申请日：2001-10-18
IPC分类号： A61L15/32 , A61L27/22 , A61L27/24 , A61L27/26 , A61L27/38 , C07K14/78 , C12N5/00 , A61L31/04 , C08L89/00 , B29C67/00 , B29C41/00 , C07K14/75
CPC分类号： C12N5/0068 , A61K2035/126 , A61L15/32 , A61L27/225 , A61L27/24 , A61L27/26 , A61L27/38 , A61L27/3847 , A61L31/041 , A61L2400/04 , B29C41/006 , B29C67/0007 , C07K14/75 , C07K14/78 , C12N5/0012 , C12N2533/40 , C12N2533/54 , C12N2533/56 , D01D5/0007 , D01F1/10 , C08L89/00
摘要： The invention is directed to novel compositions comprising an electroprocessed material and a substance, their formation and use. The electroprocessed material can, for example, be one or more natural materials, one or more synthetic materials, or a combination thereof. The substance can be one or more therapeutic or cosmetic substances or other compounds, molecules, cells, vesicles. The compositions can be used in substance delivery, including drug delivery within an organism by, for example, releasing substances or containing cells that release substances. The compositions can be used for other purposes, such as prostheses or similar implants.
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公开(公告)号：EP2585629A2
公开(公告)日：2013-05-01
申请号：EP11804120.1
申请日：2011-06-28
CPC分类号： A61F2/02 , D01D5/0061 , D01D5/0076 , D01F6/62 , D01F6/625 , D04H1/728
摘要： Electrospun materials are fabricated using air-flow impedance technology, which results in the production of scaffolds in which some regions are dense with low porosity and others regions are less dense and more porous. The dense regions provide structural support for the scaffold while the porous regions permit entry of cells and other materials into the scaffold, e.g. when used for tissue engineering.
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公开(公告)号：EP1555957A2
公开(公告)日：2005-07-27
申请号：EP03808152.7
申请日：2003-10-06
发明人： BOWLIN, Gary, L. , SIMPSON, David, G. , WNEK, Gary, E. , STEVENS, Peter, J. , CADD, Gary501 Turner Road , COHEN, I., Kelman , CARR, Marcus, Jr.
IPC分类号： A61F2/02
CPC分类号： A61L24/102 , A61F2/105 , A61F2013/00314 , A61F2013/00472 , A61K38/363 , A61K38/39 , A61L24/106 , C07K14/78 , Y10T428/298 , A61K2300/00
摘要： The present invention relates to sealants for skin and other tissues. The sealants include an electroprocessed material. The sealants may contain more than one electroprocessed materials and may contain additional substances. The invention further relates to methods of making and using such sealants.
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