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公开(公告)号：EP0193204B1
公开(公告)日：1990-06-27
申请号：EP86102657.3
申请日：1986-02-28
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公开(公告)号：EP0127179A1
公开(公告)日：1984-12-05
申请号：EP84106143.5
申请日：1984-05-29
IPC分类号： C07D257/04 , C12Q1/26
CPC分类号： C07D257/04 , C09B50/02 , C12Q1/26
摘要： An aqueous solution containing a tetrazolium compound used for determining superoxide ions can be stabilized by adding ß-cyclodextrin and/or a derivative thereof and/or γ-cyctodextrin.
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3.发明公开Method for measuring the amount of constituent contained in specific lipotrotein 失效用于测量包含在特定脂蛋白的组分的量的方法
公开(公告)号：EP0754948A1
公开(公告)日：1997-01-22
申请号：EP96111431.1
申请日：1996-07-16
发明人： Miki, Yutaka , Hanada, Toshiro , Tanaka, Kiyoko
IPC分类号： G01N33/68 , G01N33/92 , G01N33/53 , G01N33/487 , G01N21/59
CPC分类号： G01N33/92 , G01N21/59 , G01N2800/044 , Y10S435/805 , Y10S435/962 , Y10S436/805 , Y10S436/81 , Y10S436/811 , Y10S436/824 , Y10S436/825
摘要： There is provided a method for measuring the amount of objective constituent for the measurement contained in the specific lipoprotein in a living sample such as serum and plasma, specifically for measuring the amount of cholesterol contained in high density lipoprotein, which can be applicable to clinical tests.
The present invention also provides a kit for measuring the amount of the objective constituent contained in the specific lipoprotein, which comprises (i) a reagent composition containing an antibody reactive to lipoprotein(s) other than the specific lipoprotein, and a buffering agent; and (ii) a reagent composition containing a reagent for measuring the amount of the objective constituent contained in a lipoprotein and a buffering agent.摘要翻译： 提供了一种方法，用于测量目标组分的量对包含在生物样品中的特定脂蛋白的测定：如血清和血浆，特别是用于测量包含在高密度脂蛋白胆固醇的量，其可以是适用于临床试验 ， 因此，本发明提供了用于测量包含在所述特定脂蛋白的目标组分，包括（i）的试剂组合物含有抗体反应的脂蛋白（S）比所述特定脂蛋白和缓冲剂的其它的量的试剂盒; 和（ii）的试剂组合物含有试剂，用于测量包含在脂蛋白和缓冲剂的目标组分的量。
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公开(公告)号：EP0193204A3
公开(公告)日：1986-12-17
申请号：EP86102657
申请日：1986-02-28
摘要： Superoxide dismutase activity is determined by measuring hydrogen peroxide produced by using superoxide anion as a substrate and acting superoxide dismutase thereon in the presence of an electron carrier. When maleimide or a derivative thereof, and if necessary, a carbonyl compound, and if further necessary bromine ions and/or citric acid or a salt thereof are added to the electron carrier, the sensitivity and the linearity of calibration curves are further improved.
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公开(公告)号：EP0193204A2
公开(公告)日：1986-09-03
申请号：EP86102657.3
申请日：1986-02-28
摘要： Superoxide dismutase activity is determined by measuring hydrogen peroxide produced by using superoxide anion as a substrate and acting superoxide dismutase thereon in the presence of an electron carrier. When maleimide or a derivative thereof, and if necessary, a carbonyl compound, and if further necessary bromine ions and/or citric acid or a salt thereof are added to the electron carrier, the sensitivity and the linearity of calibration curves are further improved.
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6.发明公开Process for measuring body fluid components 失效Verfahren zur Messung von Bestandteilen einerKörperflüssigkeit。
公开(公告)号：EP0402094A2
公开(公告)日：1990-12-12
申请号：EP90306092.9
申请日：1990-06-05
CPC分类号： C12Q1/28
摘要： A substrate or an enzymatic activity in a body fluid can be measured accurately without influences of interfering substances such as bilirubin by reacting an oxidase corresponding to an analyte with the analyte or an oxidase corresponding to a substance produced by enzymatic reaction with the substance in a measuring system containing one or more cationic and/or amphoteric surfactants, followed by optical measurement of hydrogen peroxide produced by the reaction.
摘要翻译： 体液中的底物或酶活性可以精确测量，而不受干扰物质如胆红素的影响，通过使与分析物相应的氧化酶与对象物相对应的氧化酶或与物质的酶反应产生的物质反应 系统，其含有一种或多种阳离子和/或两性表面活性剂，随后光学测量由反应产生的过氧化氢。
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公开(公告)号：EP0223977B1
公开(公告)日：1990-10-10
申请号：EP86113651.3
申请日：1986-10-02
IPC分类号： C12Q1/28 , C12Q1/26 , G01N33/535
CPC分类号： G01N33/548 , C12Q1/28
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公开(公告)号：EP0149853A2
公开(公告)日：1985-07-31
申请号：EP84116437.9
申请日：1984-12-28
IPC分类号： C12Q1/32
CPC分类号： C12Q1/32
摘要： In a process for measuring the activity of a dehydrogenase or the amount of substrate reacted in the presence of the dehydrogenase using NAD or NADP as coenzyme and a tetrazorium salt as a color-producing reagent, when at least one member selected from the group consisting of dodecyl sulfate, decyl sulfate, dodecylbenzenesulfonic acid, and salts thereof is used, deposition and staining of a formazan compound produced can be prevented and improvement in color-producing stability and enhancement of coloring can be attained.
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公开(公告)号：EP0821239A3
公开(公告)日：1998-06-17
申请号：EP97112537.2
申请日：1997-07-22
发明人： Miki, Yutaka , Imajo, Nobuko , Hanada, Toshiro
CPC分类号： G01N33/92 , G01N2800/044 , Y10S435/975
摘要： The present invention is to provide a method for measuring an amount of cholesterol in low density lipoproteins (LDL-cholesterol) in a sample specifically at high accuracy and a reagent used in this method, and the present invention can attain such effect that direct measuring an amount of LDL-cholesterol by widely used automatic analyzers can be conducted by using the invention, which has not been possible after known methods.
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