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公开(公告)号：EP2408930B1
公开(公告)日：2015-05-06
申请号：EP10723158.1
申请日：2010-03-10
申请人： WALLAC OY
发明人： KARVINEN, Jarkko , HURSKAINEN, Pertti , MATTSSON, Pekka , MULARI, Outi , PEURALAHTI, Jari , JAAKKOLA, Lassi
CPC分类号： C12Q1/37 , G01N2333/98
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2.发明公开LUMINESCENT LANTHANIDE (III) CHELATES, CHELATING AGENTS AND CONJUGATES DERIVED THEREOF 有权发光镧系元素（III）螯合物，螯合剂和衍生结合物
公开(公告)号：EP2195310A1
公开(公告)日：2010-06-16
申请号：EP08805417.6
申请日：2008-09-05
申请人： Wallac OY
发明人： PEURALAHTI, Jari , HOVINEN, Jari , KETOLA, Janne , JAAKKOLA, Lassi , MUKKALA, Veli-Matti , LIITTI, Päivi
IPC分类号： C07D405/14 , C07D409/14 , G01N33/52 , G01N33/58
CPC分类号： C07D405/14 , C07D409/14 , G01N33/533 , G01N33/543 , G01N33/582
摘要： This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained. The chelates described herein compris - a lanthanide ion, Ln 3+ - chromophoric moiety - a chelating part, and - a reactive group.
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公开(公告)号：EP1979307A1
公开(公告)日：2008-10-15
申请号：EP07700284.8
申请日：2007-01-16
申请人： Wallac OY
IPC分类号： C07C237/06 , C07C331/28 , C07J7/00 , C07C237/04 , C07C229/16 , G01N33/533 , G01N33/58
CPC分类号： C07C229/76 , A61K49/085 , A61K49/10 , A61K49/103 , A61K51/0478 , C07C251/60 , C07C331/28 , G01N33/533
摘要： This invention concerns novel neutral labeling reactants. The novel reactants are deri- vatives of diethylenetriaminepentaacetic acid (DTPA) diamides, wherein a suitable group is linked to the molecule allowing introduction of the said neutral chelate to bioactive molecules.
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公开(公告)号：EP1658282A1
公开(公告)日：2006-05-24
申请号：EP04767016.1
申请日：2004-08-27
申请人： WALLAC OY
IPC分类号： C07D405/04 , C07D405/14 , C07D471/16 , C07F9/48 , G01N33/52 , G01N33/58
CPC分类号： G01N33/587 , C07D405/04 , C07D405/14 , C07F9/65586 , G01N33/582
摘要： This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.
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5.发明授权LUMINESCENT LANTHANIDE (III) CHELATES, CHELATING AGENTS AND CONJUGATES DERIVED THEREOF 有权发光镧系元素（III）螯合物，螯合剂和衍生结合物
公开(公告)号：EP2195310B1
公开(公告)日：2016-06-01
申请号：EP08805417.6
申请日：2008-09-05
申请人： Wallac OY
发明人： PEURALAHTI, Jari , HOVINEN, Jari , KETOLA, Janne , JAAKKOLA, Lassi , MUKKALA, Veli-Matti , LIITTI, Päivi
IPC分类号： C07D405/14 , C07D409/14 , G01N33/52 , G01N33/58
CPC分类号： C07D405/14 , C07D409/14 , G01N33/533 , G01N33/543 , G01N33/582
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6.发明授权NOVEL CHELATING AGENTS AND HIGHLY LUMINESCENT AND STABLE CHELATES AND THEIR USE 有权新螯合剂和高发光和稳定的螯合物及其应用
公开(公告)号：EP1694672B1
公开(公告)日：2012-06-20
申请号：EP04798289.7
申请日：2004-11-15
申请人： WALLAC OY
IPC分类号： C07D405/04 , C07D405/14 , C07D471/16 , C07F9/48 , G01N33/52 , G01N33/58 , C12Q1/68
CPC分类号： C07D401/14 , C07D213/38 , C07F9/588 , C07F9/65121 , C07F9/6515 , C07F9/6524 , G01N33/532
摘要： This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.
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公开(公告)号：EP2408930A2
公开(公告)日：2012-01-25
申请号：EP10723158.1
申请日：2010-03-10
申请人： WALLAC OY
发明人： KARVINEN, Jarkko , HURSKAINEN, Pertti , MATTSSON, Pekka , MULARI, Outi , PEURALAHTI, Jari , JAAKKOLA, Lassi
CPC分类号： C12Q1/37 , G01N2333/98
摘要： The present technology discloses biotinidase assay, biotinidase substrates (I) and a kit wherein the biotinidase substrate includes a label molecule separated from the biotin carbamoyl group by a linker X longer than about 4Å but shorter than about 27Å.
摘要翻译： 本技术公开了生物素酰胺酶测定法，生物素酰胺酶底物（I）和其中生物素化酶底物包括通过大于约4但小于约27的接头X与生物素氨基甲酰基分离的标记分子的试剂盒。
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公开(公告)号：EP1658282B1
公开(公告)日：2010-10-27
申请号：EP04767016.1
申请日：2004-08-27
申请人： WALLAC OY
IPC分类号： C07D405/04 , C07D405/14 , C07D471/16 , C07F9/48 , G01N33/52 , G01N33/58
CPC分类号： G01N33/587 , C07D405/04 , C07D405/14 , C07F9/65586 , G01N33/582
摘要： This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.
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9.发明公开NOVEL CHELATING AGENTS AND HIGHLY LUMINESCENT AND STABLE CHELATES AND THEIR USE 有权新螯合剂和高发光和稳定的螯合物及其应用
公开(公告)号：EP1694672A1
公开(公告)日：2006-08-30
申请号：EP04798289.7
申请日：2004-11-15
申请人： WALLAC OY
IPC分类号： C07D405/04 , C07D405/14 , C07D471/16 , C07F9/48 , G01N33/52 , G01N33/58 , C12Q1/68
CPC分类号： C07D401/14 , C07D213/38 , C07F9/588 , C07F9/65121 , C07F9/6515 , C07F9/6524 , G01N33/532
摘要： This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.
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