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公开(公告)号：EP4434626A1
公开(公告)日：2024-09-25
申请号：EP22894720.6
申请日：2022-11-11
申请人： Xiamen University , Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. , Xiamen Innodx Biotech Co., Ltd
发明人： ZHANG, Dongxu , GAO, Runxin , HUANG, Shaolei , HUANG, Yulin , LIU, Guoqiang , YANG, Jiayu , ZENG, Juntian , SONG, Liuwei , GE, Shengxiang , ZHANG, Jun , XIA, Ningshao
摘要： The present disclosure relates to a microfluidic chip and a microfluidic chip detection system. The microfluidic chip including: a storage member provided with a groove therein, at least two storage chambers being disposed around the groove; a base disposed at one end of the storage member away from the groove, a reaction chamber being disposed on the base; and a valve disposed in the groove, the valve being configured to operatively communicate any one of the at least two storage chambers with the reaction chamber. The present disclosure can lead the solution in any storage chamber to the reaction chamber or lead the solution in the reaction chamber to any storage chamber by operating the valve, so that the solution transfer is realized, the structure is simple and compact, the length of the flow channels can be greatly shortened, and the detection efficiency is improved.
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公开(公告)号：EP4086274A1
公开(公告)日：2022-11-09
申请号：EP20909593.4
申请日：2020-12-25
发明人： LI, Tingdong , GE, Shengxiang , GUO, Xiaoyi , HONG, Congming , SONG, Liuwei , WEN, Shunhua , TANG, Jiabao , ZHANG, Jun , XIA, Ningshao
IPC分类号： C07K14/435 , C07K14/00 , G01N33/68 , G01N33/574 , G01N33/569
摘要： Provided are a method for diagnosing nasopharyngeal carcinoma on the basis of the anti-EB virus (EBV) antibody level and a kit used for the method. Also provided are a polypeptide encoded by a BNLF2b gene in EB virus used for the above-mentioned diagnosis and the use thereof for diagnosing nasopharyngeal carcinoma.
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公开(公告)号：EP4092050A1
公开(公告)日：2022-11-23
申请号：EP21741247.7
申请日：2021-01-18
发明人： CHEN, Zimin , XIONG, Junhui , LIU, Jiaqi , WANG, Shaojuan , GE, Shengxiang , YUAN, Quan , SONG, Liuwei , SUN, Xudong
IPC分类号： C07K16/18
摘要： In the field of Hepatitis B virus (HBV) detection, disclosed are a method for detecting HBcAg by means of using a double antibody sandwich method, and an antibody and kit for detecting HBcAg; also included is a monoclonal antibody that can be used in the immunological detection of HBcAg in a tissue or cell sample.
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公开(公告)号：EP3885363A1
公开(公告)日：2021-09-29
申请号：EP19888178.1
申请日：2019-11-06
发明人： XIONG, Junhui , CHEN, Zimin , XU, Weiling , WANG, Long , KE, Qishen , LI, Lihua , SONG, Liuwei , SUN, Xudong , GE, Shengxiang
IPC分类号： C07K16/26 , C12N5/20 , G01N33/74 , G01N33/577
摘要： The present invention belongs to the field of biomedical laboratory science, and provides a specific antibody for AMH and uses thereof.
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5.发明公开
公开(公告)号：EP4406967A1
公开(公告)日：2024-07-31
申请号：EP22871531.4
申请日：2022-06-30
发明人： WANG, Haihong , KE, Qishen , ZOU, Mengwen , ZHUANG, Cuizhen , LI, Lihua , LI, Huiping , CHEN, Weibin , KE, Shaojun , ZHANG, Yifei , LIN, Qiumin , SONG, Liuwei , XIONG, Junhui
CPC分类号： C12N15/866 , G01N33/68 , C07K19/00 , C12N5/10 , C07K14/72
摘要： The present invention provides a recombinant thyroid stimulating hormone receptor protein, a preparation method therefor and an application thereof. The recombinant thyroid stimulating hormone receptor protein comprises a TSHR protein extracellular segment and a TSHR protein intracellular segment. The C-terminus of the TSHR protein extracellular segment is linked to the N-terminus of the TSHR protein intracellular segment. The protein achieves extracellular soluble expression, and is high in purity, high in activity and good in stability.
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6.发明授权
公开(公告)号：EP2805729B1
公开(公告)日：2019-01-09
申请号：EP13738450.9
申请日：2013-01-17
发明人： YUAN, Quan , SONG, Liuwei , ZHOU, Wenbin , WENG, Zuxing , XU, Feihai , GE, Shengxiang , ZHANG, Jun , XIA, Ningshao
IPC分类号： G01N33/569 , G01N33/576
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7.发明公开ANTI-HBC QUANTITATIVE DETECTION METHOD AND USES THEREOF IN MONITORING AND CONTROLLING DISEASE PROGRESSION OF CHRONIC HEPATITIS B PATIENT AND IN PREDICTING THERAPEUTIC EFFECT 有权对于定量检测抗HBC方法及其用途的监视和控制病程的慢性乙肝患者，并在治疗效果的预测
公开(公告)号：EP2805729A1
公开(公告)日：2014-11-26
申请号：EP13738450.9
申请日：2013-01-17
发明人： YUAN, Quan , SONG, Liuwei , ZHOU, Wenbin , WENG, Zuxing , XU, Feihai , GE, Shengxiang , ZHANG, Jun , XIA, Ningshao
CPC分类号： G01N33/56983 , G01N33/5762 , G01N2333/02 , G01N2469/20 , G01N2800/52 , G01N2800/56
摘要： The present invention relates to a method for quantitative detection of anti-HBc and its use in monitoring disease progression of chronic hepatitis B patients and predicting therapeutic effects. By quantitative detection of antibodies against hepatitis B core protein (Anti-HBc), it is able to monitor disease progression of chronic hepatitis B patients, effectively predict therapeutic effects in chronic hepatitis B patients who accept a therapy against hepatitis B virus (especially, a therapy based on interferon and a therapy based on nucleoside/nucleotide analogue anti-HBV drug), and thus guide the patients to reasonably choose drugs.
摘要翻译： 本发明涉及用于抗-HBc的定量检测及其在监测慢性乙型肝炎患者的疾病进展和预测治疗效果的使用的方法。 通过对乙型肝炎核心蛋白（抗-HBc）抗体的定量检测，它能够监测慢性乙型肝炎患者的疾病进展，有效地预测谁接受抗乙肝病毒治疗（尤其是慢性乙肝患者的治疗效果，一 治疗基于干扰素和基于核苷/核苷酸类似物的抗HBV药物治疗），因而指导患者合理选择药物。
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