专利检索 ap:("YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD") AND inv:"CERN, Ahuva" 第 1 页

1.

发明公开
LIPOSOMAL FORMULATIONS COMPRISING AT1 RECEPTOR BLOCKERS AND USES THEREOF 审中-公开

公开(公告)号：EP4125809A1

公开(公告)日：2023-02-08

申请号：EP21718237.7

申请日：2021-03-25

申请人： YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD

发明人： BARENHOLZ, Yechezkel , CERN, Ahuva , GOLDBLUM, Amiram

IPC分类号： A61K9/00 , A61K9/127 , A61K31/41 , A61K31/4178 , A61K31/4184 , A61K31/4245 , A61K47/12 , A61K47/40

2.

发明公开
LIPOSOMAL MUPIROCIN 审中-公开
标题翻译：利培酮MUPIROCIN

公开(公告)号：EP3142642A1

公开(公告)日：2017-03-22

申请号：EP15722359.5

申请日：2015-04-08

申请人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

发明人： BARENHOLZ, Yechezkel , GOLDBLUM, Amiram , CERN, Ahuva

IPC分类号： A61K9/127 , A61K31/351 , A61K47/40 , A61K47/69

CPC分类号： A61K9/1271 , A61K31/351 , A61K47/40 , A61K47/6951 , Y02A50/411

摘要： Provided are liposomes encapsulating mupirocin, with particular benefit for systemic therapeutically effective delivery. Also provided herein are pharmaceutical compositions including the liposomes and methods of using them. The liposomes include a lipid membrane and an intraliposomal compartment, the intraliposomal compartment encapsulating mupirocin, at least one cyclodextrin compound and a pH dependent ionizable anion, e.g. acetate.

摘要翻译： 提供包封莫匹罗星的脂质体，特别有益于全身治疗有效递送。本文还提供包含脂质体的药物组合物及其使用方法。脂质体包括脂质膜和脂质体内隔室，包封莫匹罗星的脂质体内区域，至少一种环糊精化合物和pH依赖性可电离阴离子，例如，醋酸。

3.

发明公开
LIPOSOMAL CANNABINOIDS AND USES THEREOF 审中-公开

公开(公告)号：EP4037662A1

公开(公告)日：2022-08-10

申请号：EP20792754.2

申请日：2020-10-01

申请人： YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD

发明人： BARENHOLZ, Yechezkel , CERN, Ahuva

IPC分类号： A61K9/00 , A61K9/127 , A61K31/352 , A61K47/10 , A61K47/26 , A61K47/40 , A61K47/42 , A61P25/00

4.

发明公开
PHARMACEUTICAL COMPOSITIONS COMPRISING A COMBINATION OF OPIOID ANTAGONISTS 审中-公开

公开(公告)号：EP4013390A1

公开(公告)日：2022-06-22

申请号：EP20760938.9

申请日：2020-08-12

申请人： YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD

发明人： BARENHOLZ, Yechezkel , CERN, Ahuva

IPC分类号： A61K9/127 , A61K31/485 , A61K31/5377 , A61K9/06 , A61K47/34 , A61K9/00

5.

发明公开
PROTEIN-BOUND CANNABINOID FORMULATIONS AND USES THEREOF 审中-公开

公开(公告)号：EP4221683A1

公开(公告)日：2023-08-09

申请号：EP21791043.9

申请日：2021-09-30

申请人： YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD

发明人： BARENHOLZ, Yechezkel , CERN, Ahuva

IPC分类号： A61K9/00 , A61K9/08 , A61K47/42 , A61K47/50 , A61K31/352 , A61P25/04

6.

发明授权
LIPOSOMAL MUPIROCIN 有权

公开(公告)号：EP3142642B1

公开(公告)日：2018-08-29

申请号：EP15722359.5

申请日：2015-04-08

申请人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

发明人： BARENHOLZ, Yechezkel , GOLDBLUM, Amiram , CERN, Ahuva

IPC分类号： A61K9/127 , A61K31/351 , A61K47/40 , A61K47/69

CPC分类号： A61K9/1271 , A61K31/351 , A61K47/40 , A61K47/6951 , Y02A50/411

摘要： Provided are liposomes encapsulating mupirocin, with particular benefit for systemic therapeutically effective delivery. Also provided herein are pharmaceutical compositions including the liposomes and methods of using them. The liposomes include a lipid membrane and an intraliposomal compartment, the intraliposomal compartment encapsulating mupirocin, at least one cyclodextrin compound and a pH dependent ionizable anion, e.g. acetate.