公开(公告)号：EP2282195A3

公开(公告)日：2011-09-28

申请号：EP10170178.7

申请日：2010-07-20

申请人： Yokogawa Electric Corporation

发明人： Tanaami, Takeo ,  Aoki, Hidetoshi ,  Sugiyama, Yumiko ,  Shimoda, Souichirou ,  Araragi, Muneki

IPC分类号： G01N21/64

CPC分类号： G01N21/6452 ,  G01N21/6428

摘要： An amount of fluorescent light (5) generated from the specimen (4) is quantitatively measured as "a light-amount value per unit area traceable to the national standard" instead of in terms of a ratio (a ratio value) as in the past. A method for measuring a fluorescent light amount, whereby a specimen (4) is irradiated with excitation light (2), and fluorescent light (5) generated from the specimen (4) is measured by a light-receiving element via a receiving optical system (6), said method comprising the steps of irradiating the specimen (4) with excitation light (2) having a light-amount value per specified unit area traceable to the national standard, and designated on the surface of the specimen (4) beforehand, causing the light-receiving element to measure the fluorescent light (5) generated from the specimen (4) via the receiving optical system (6), and computing a fluorescent light-amount as measured by the light-receiving element via the receiving optical system (6) on the basis of an excitation light-amount per the specified unit area, optical coefficients of the receiving optical system (6), and the acceptance coefficient of the light-receiving element, thereby working out a light amount value per the unit area traceable to the national standard.

公开(公告)号：EP2947140B1

公开(公告)日：2018-05-23

申请号：EP15164245.1

申请日：2015-04-20

申请人： Yokogawa Electric Corporation

发明人： Namatame, Tetsushi ,  Shimoda, Souichirou ,  Suzuki, Yasuyuki ,  Izaki, Fumiaki

IPC分类号： C12M1/34 ,  C12M1/36

CPC分类号： C12M41/12 ,  C12M41/00 ,  C12M41/26 ,  C12M41/32 ,  C12M41/38 ,  C12M41/40 ,  C12M41/48

摘要： A cell culture control system includes a controller configured to control parameters of a culture fluid which exists in a processor in accordance with a control value which is preliminarily set, a generator configured to generate time-series data by using a concentration value of the metabolic substances in the culture fluid, the concentration value of the metabolic substances being detected by a sensor, an extractor configured to extract a characteristic point of the time-series data generated by the generator, and a control value setter configured to change the control value in accordance with the characteristic point extracted by the extractor.

公开(公告)号：EP2947140A1

公开(公告)日：2015-11-25

申请号：EP15164245.1

申请日：2015-04-20

申请人： Yokogawa Electric Corporation

发明人： Namatame, Tetsushi ,  Shimoda, Souichirou ,  Suzuki, Yasuyuki ,  Izaki, Fumiaki

IPC分类号： C12M1/36

CPC分类号： C12M41/12 ,  C12M41/00 ,  C12M41/26 ,  C12M41/32 ,  C12M41/38 ,  C12M41/40 ,  C12M41/48

摘要： A cell culture control system includes a controller configured to control parameters of a culture fluid which exists in a processor in accordance with a control value which is preliminarily set, a generator configured to generate time-series data by using a concentration value of the metabolic substances in the culture fluid, the concentration value of the metabolic substances being detected by a sensor, an extractor configured to extract a characteristic point of the time-series data generated by the generator, and a control value setter configured to change the control value in accordance with the characteristic point extracted by the extractor.

摘要翻译： 细胞培养控制系统包括：控制器，被配置为根据预先设定的控制值来控制存在于处理器中的培养液的参数;发生器，被配置为通过使用代谢物质的浓度值来生成时间序列数据 在培养液中，由传感器检测到的代谢物质的浓度值，被配置为提取由发生器生成的时间序列数据的特征点的提取器，以及被配置为根据发生器改变控制值的控制值设定器 提取器提取特征点。

公开(公告)号：EP2282195A2

公开(公告)日：2011-02-09

申请号：EP10170178.7

申请日：2010-07-20

申请人： Yokogawa Electric Corporation

发明人： Tanaami, Takeo ,  Aoki, Hidetoshi ,  Sugiyama, Yumiko ,  Shimoda, Souichirou ,  Araragi, Muneki

IPC分类号： G01N21/64

CPC分类号： G01N21/6452 ,  G01N21/6428

摘要： An amount of fluorescent light (5) generated from the specimen (4) is quantitatively measured as "a light-amount value per unit area traceable to the national standard" instead of in terms of a ratio (a ratio value) as in the past. A method for measuring a fluorescent light amount, whereby a specimen (4) is irradiated with excitation light (2), and fluorescent light (5) generated from the specimen (4) is measured by a light-receiving element via a receiving optical system (6), said method comprising the steps of irradiating the specimen (4) with excitation light (2) having a light-amount value per specified unit area traceable to the national standard, and designated on the surface of the specimen (4) beforehand, causing the light-receiving element to measure the fluorescent light (5) generated from the specimen (4) via the receiving optical system (6), and computing a fluorescent light-amount as measured by the light-receiving element via the receiving optical system (6) on the basis of an excitation light-amount per the specified unit area, optical coefficients of the receiving optical system (6), and the acceptance coefficient of the light-receiving element, thereby working out a light amount value per the unit area traceable to the national standard.

摘要翻译： （5）从所述样品（4）的定量测​​量为“每单位面积的光量值可溯源至国家标准”，而不是在一个比计（比例值）作为在过去产生的荧光的光量 ， 一种用于测量荧光的光量，由此，试样（4）照射从试样产生的激发光（2），和荧光灯（5）方法（4）是由一个受光元件经由受光光学系统测量 （6）所述的方法包括用（2），其具有指定的每单位面积的可溯源至国家标准的光量值的激励光照射在试样（4）的步骤，和（4）预先指定的试样的表面上 ，使光接收元件来测量荧光的（5）经由所述受光光学系统（6），并计算荧光光量从样品（4）产生经由受光光学由光接收元件所测量 系统（6）每指定单位面积的激励光量的基础上，所述受光光学系统（6），以及光接收元件的受系数的光学系数，从而制定出每一个光量值 UNI T区可溯源至国家标准。