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公开(公告)号:EP3781952B1
公开(公告)日:2024-10-16
申请号:EP19718176.1
申请日:2019-04-19
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公开(公告)号:EP4436940A1
公开(公告)日:2024-10-02
申请号:EP22826135.0
申请日:2022-11-21
申请人: Safran Ceramics , Centre National de la Recherche Scientifique (CNRS) , Université Paul Sabatier Toulouse III , Institut National Polytechnique de Toulouse
发明人: PIN, Lisa , ARNAL, Simon , PRIOUX, Manon , ANSART, Florence , DULUARD, Sandrine
IPC分类号: C04B41/45 , C04B41/00 , C04B41/52 , C04B41/89 , F01D5/28 , C23C28/04 , C25D13/02 , C25D13/12
CPC分类号: C04B41/009 , C04B41/89 , C04B41/52 , C04B41/4564 , C23C28/04 , F01D5/288 , C25D13/12 , C25D13/02 , F01D5/284 , F05D2300/603320130101 , C23C28/042
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公开(公告)号:EP4407026A2
公开(公告)日:2024-07-31
申请号:EP24179144.1
申请日:2020-05-26
IPC分类号: C12N9/12
CPC分类号: C12P19/34 , C12N9/1264
摘要: The present invention relates to variants of Terminal deoxynucleotidyl Transferase (TdT), each of which (i) has an amino acid sequence selected from SEQ ID NOs 10-35, or a functionally equivalent sequence, with at least an amino acid substitution at the position corresponding to residue C302 (with respect to SEQ ID NO: 1) or a functionally equivalent residue in SEQ ID NOs 10-35, respectively, (ii) is able to synthesize a nucleic acid fragment without a template and (iii) is able to incorporate a 3'-O-modified nucleotide into the nucleic acid fragment.
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5.
公开(公告)号:EP4405412A1
公开(公告)日:2024-07-31
申请号:EP22792847.0
申请日:2022-09-22
申请人: UNIVERSITE DE MONTPELLIER , Université Grenoble Alpes , Centre National de la Recherche Scientifique (CNRS) , Ecole Nationale Supérieure de Chimie de Montpellier
IPC分类号: C08G65/332 , C08G65/334 , C08G65/333 , C08G65/26
CPC分类号: C08G65/3322 , C08G65/334 , C08G65/33306 , C08G65/2615
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6.
公开(公告)号:EP3274103B1
公开(公告)日:2024-07-31
申请号:EP16713392.5
申请日:2016-03-25
CPC分类号: B05D3/0254 , H05B6/6491 , B05D2202/0020130101 , H05B6/6455 , H05B6/80
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公开(公告)号:EP3972631B1
公开(公告)日:2024-07-10
申请号:EP20726457.3
申请日:2020-05-20
CPC分类号: A61K38/46 , C12N15/86 , A01K2227/10520130101 , A01K2217/07520130101 , A61K48/005 , C12N9/6421 , A61P43/00 , A61P25/00
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8.
公开(公告)号:EP4380600A1
公开(公告)日:2024-06-12
申请号:EP22757593.3
申请日:2022-07-29
申请人: Universidade de Santiago de Compostela , Centre National de la Recherche Scientifique (CNRS) , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , Université d'Angers
发明人: MILBANK, Edward , LÓPEZ PÉREZ, Miguel Antonio , MARTINEZ MARTINEZ, María Del Carmen , ANDRIANTSITOHAINA, Ramaroson
IPC分类号: A61K38/45 , A61P3/04 , A61K35/15 , C12N15/52 , C12N5/0784
CPC分类号: A61K38/45 , C12Y207/11026 , A61P3/04 , A61K35/15 , C12N5/0639 , A61K48/0041 , A01K2227/10520130101 , A01K2217/07520130101
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公开(公告)号:EP4376831A1
公开(公告)日:2024-06-05
申请号:EP22762123.2
申请日:2022-07-28
申请人: Mexbrain , Université Claude Bernard Lyon I , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS-
发明人: TILLEMENT, Olivier , LUX, François , BRICHART, Thomas , GRANGE, Coralie , NATUZZI, Marco , HOWARD, Jordyn , SALAZAR ARIZA, Juan , COUTURIER, Aymeric , ROSSETTI, Fabien
IPC分类号: A61K31/395 , A61K31/715 , A61M1/16 , A61P39/04
CPC分类号: A61K31/715 , A61K31/395 , A61M1/1654 , A61P39/04
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