公开(公告)号：EP1910845A2

公开(公告)日：2008-04-16

申请号：EP06786813.3

申请日：2006-07-11

申请人： DADE BEHRING INC.

发明人： MILLER, Kerry, Lynn

IPC分类号： G01N35/00

CPC分类号： G01N35/0092 ,  B04B2011/046 ,  Y10T436/111666

摘要： A method for automatically providing for classification of samples at the input station of a clinical laboratory workcell and allowing only those samples that have centrifuging requirements which are satisfied by currently established centrifuge operating protocols to be processed by a centrifuge and by an analyzer associated with said workcell.

公开(公告)号：EP1825255A1

公开(公告)日：2007-08-29

申请号：EP05813040.2

申请日：2005-10-25

申请人： DADE BEHRING INC.

发明人： CLARK, Douglas, Paul

IPC分类号： G01N33/20

CPC分类号： G01N33/96 ,  Y10T436/10 ,  Y10T436/106664 ,  Y10T436/108331 ,  Y10T436/175383 ,  Y10T436/204165 ,  Y10T436/204998

摘要： A multi-analyte calibration solution having known amounts of sodium carbonate, ammonium bicarbonate, and ethyl alcohol, with pH adjusted within a range between about 7.8 and 8.4.

公开(公告)号：EP1414573B1

公开(公告)日：2007-04-18

申请号：EP02789156.3

申请日：2002-07-30

申请人： DADE BEHRING INC.

发明人： GEBRIAN, Peter, Louis ,  CAMERON, Allan, Lee ,  MUDD, Alan, Christopher ,  MCDERMOTT, Patrick, Francis ,  WEST, Adrian, Mark, Thomas

IPC分类号： B01L3/00

CPC分类号： G01N35/00029 ,  B01L3/502715 ,  B01L3/50855 ,  B01L9/527 ,  B01L2300/0803 ,  B01L2300/0809 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0457 ,  B01L2400/0688 ,  G01N35/00069 ,  G01N2035/00089 ,  G01N2035/00148 ,  Y10S435/809

摘要： An elongate canister (18) having a generally rectangular cross-section sized to house a plurality of antibiotic susceptibilty test arrays (12) stacked one atop another and maintained secure within an environmentaly controlled inventory chamber (22) in a random access microbiological analyzer (10).

公开(公告)号：EP1747470A2

公开(公告)日：2007-01-31

申请号：EP05748310.9

申请日：2005-05-06

申请人： DADE BEHRING INC.

发明人： DEVLIN, William, Jackson

IPC分类号： G01N35/00

CPC分类号： G01N35/025 ,  G01N35/00594 ,  G01N35/00712 ,  G01N35/026 ,  G01N2035/0458

摘要： A biochemical analyzer adapted to automatically perform calibration and quality control protocols using shuttles adapted to remove calibration and quality control solution vials from a loading tray and to inventory said solution vials on board the biochemical analyzer in a calibration and quality control solution server. In addition, the analyzer is adapted to automatically penetrate the closure covering the opening of the calibration and quality control solution vials, aspirate an amount of solution therefrom and dispense said solution into a test cuvette, thereby eliminating the previous need for operator intervention.

公开(公告)号：EP1733230A1

公开(公告)日：2006-12-20

申请号：EP05725700.8

申请日：2005-03-16

申请人： DADE BEHRING INC.

发明人： ZHENG, Yi, Feng ,  LIU, Hshiou-Ting ,  YAMOUT, Khaled, A. ,  BERGER, Donald, E. ,  HU, Mae, W.

IPC分类号： G01N33/531 ,  G01N33/533 ,  G01N33/53 ,  C07K16/00 ,  C07K17/06 ,  C07C211/48

CPC分类号： C12N9/0006 ,  G01N33/946 ,  Y10S435/961 ,  Y10S435/975

摘要： Methods, compositions and kits are disclosed. Enzyme conjugates of Formula I may be employed in assays for the determination of an amphetamine and/or a methamphetamine. Immunogenic conjugates of Formula I may be employed to prepare antibodies for an amphetamine and/or for a methamphetamine for use in assays for the determination of an amphetamine and/or a methamphetamine. The enzyme conjugates may also be employed to screen antibodies for use in such methods.

公开(公告)号：EP1206493B1

公开(公告)日：2006-11-15

申请号：EP00953792.9

申请日：2000-08-02

申请人： DADE BEHRING INC.

发明人： KASPER, Kenneth, C. ,  JEONG, Henry ,  DAVALIAN, Dariush ,  LIU, Hshiou-Ting ,  MILLER, Paul, L. ,  WILLIAMS, Denise, L.

IPC分类号： C07K16/00

CPC分类号： A61K51/1093 ,  C07K16/1292 ,  Y10S436/815

摘要： An IgG1 lambda monoclonal antibody to the immunosuppressive drug tacrolimus has improved properties. In particular, this monoclonal antibody, designated 1H6, has reduced cross-reactivity to several tacrolimus metabolites. This antibody is suitable for performance of immunoassays such as homogeneous immunoassays to detect or determine the presence or concentration of tacrolimus in samples such as blood samples. The invention further includes derivatives of tacrolimus derivatized at a non-binding portion of the molecule useful in immunizing antibody-producing animals and in producing such monoclonal antibodies, as well as labeled derivatives of tacrolimus useful as tacrolimus analogues in such assays. The invention further includes immunoassay methods for the detection of tacrolimus and test kits useful in performing such immunoassays.

公开(公告)号：EP1465728B1

公开(公告)日：2006-08-09

申请号：EP02797345.2

申请日：2002-12-17

申请人： DADE BEHRING INC.

发明人： FARINA, Edward, Francis ,  FERGUSON, Samuel, Garfield, Jr.

IPC分类号： B01L3/00 ,  B01L9/00

CPC分类号： B01L3/5085 ,  B01L2200/025 ,  B01L2300/0829 ,  G01N2035/0424 ,  G01N2035/0425 ,  G01N2035/0427

摘要： An aliquot vessel array (102) having a base plate (116) with an upper surface (117) and lower surface (115) with a pair of parallel sidewalls (118). A pair of parallel rails (136) depends downwardly from the base plate (116), and each rail (136) has a foot section (138) at its lower extremity. An array of open test wells (128) are formed on the base plate (116) between the pair of parallel sidewalls (118) and extend upwardly from the base plate (116). The sidewalls (118) are attached to the array of open wells (128) by notched side flanges (121), which mate with the foot section (138) of the rails (136).

公开(公告)号：EP1648697A2

公开(公告)日：2006-04-26

申请号：EP04778405.3

申请日：2004-07-15

申请人： DADE BEHRING INC.

发明人： MIZZER, John, Paul ,  FRYE, Stephen, Lawrence ,  DEVLIN, William, Jackson, Sr. ,  CHOW, Allan, Tit-Shing

IPC分类号： B32B27/04 ,  B32B27/12 ,  B32B5/02 ,  G01N35/00 ,  G01N35/02 ,  G01N35/08

CPC分类号： G01N35/1081 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/119163

摘要： An automatic clinical analyzer in which the number of cuvette ports available for reaction vessels on a reaction carousel are 50% in a configuration using a single reagent storage areas; in a second configuration an additional reagent storage areas is employed and additional ones of the cuvette ports on reaction carousel are utilized, thereby significantly increasing throughput.

公开(公告)号：EP1648639A2

公开(公告)日：2006-04-26

申请号：EP04757036.1

申请日：2004-07-15

申请人： DADE BEHRING INC.

发明人： CHOW, Allan, Tit-Shing ,  DEVLIN, William, Jackson, Sr. ,  EVERS, Timothy, Patrick ,  THOMPSON, David, Russell

IPC分类号： B23B5/02

CPC分类号： G01N35/025 ,  G01N21/76 ,  Y10T436/115831

摘要： An automated analyzer (10) for analyzing patient samples. The analyzer (10) includes a plurality of cuvettes (24), which allow the samples to be mixed with various reagents. The analyzer (10) includes one or more detectors (17A-D), including a detector adapted to detect luminescence of the reaction mixture in the cuvettes (24). The analyzer allows for various diagnostic assays to be performed on a single system, and provides for high sensitivity analysis at faster speeds.

摘要翻译： 一种用于分析患者样本的自动分析器（10）。 分析仪（10）包括多个比色杯（24），其允许样品与各种试剂混合。 分析器（10）包括一个或多个检测器（17A-D），其包括适于检测反应杯（24）中的反应混合物的发光的检测器。 该分析仪允许在单个系统上执行各种诊断分析，并以更快的速度提供高灵敏度分析。

公开(公告)号：EP1648608A2

公开(公告)日：2006-04-26

申请号：EP04757022.1

申请日：2004-07-15

申请人： DADE BEHRING INC.

发明人： LEE, Ching-Cherng ,  HUYNH-BA, Thai ,  PHILLIPS, Donald, Richard ,  EVERS, Timothy, Patrick

IPC分类号： B01L3/00

CPC分类号： G01N21/03 ,  B01L3/508 ,  B01L3/5082 ,  B01L2300/0654 ,  B01L2300/165

摘要： A reaction cuvette having anti-wicking wall fillets that inhibit liquid wicking along an interior wall surface so that the reaction cuvette may be used in a cuvette-rewashing system in an automated analyzer and not be adversely affected by any reagent contaminants remaining from assays previously performed in said reaction cuvette. The anti-wicking wall fillets comprise a curvilinear taper extending from an open top downwards into the cuvette to form a rounded concave blend between the cuvette's front and back walls and side walls.