-
1.发明公开AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 审中-公开氨基丙二醇衍生物，工艺用于生产药物组合物适当地使用该
公开(公告)号：EP2786982A4
公开(公告)日：2015-04-15
申请号：EP12808109
申请日：2012-07-05
发明人： HAN WEIJUAN , ZHANG HAIJING , WANG XIAOJIAN , JIN JING , LI GANG , ZHANG YI , XIAO QIONG , ZHOU WANQI , CHEN XIAOGUANG , YIN DALI
IPC分类号： C07C215/38 , A61K31/137 , A61K31/341 , A61K31/40 , A61K31/4164 , A61K31/421 , A61K31/426 , A61K31/505 , A61P37/02 , A61P37/04 , A61P37/06 , C07C31/44 , C07C217/48 , C07C217/56 , C07C323/32 , C07D207/333 , C07D263/32 , C07D277/24 , C07D277/26 , C07D307/28
CPC分类号： C07D307/52 , A61K31/137 , A61K31/341 , A61K31/40 , A61K31/4164 , A61K31/421 , A61K31/426 , A61K31/505 , C07C217/64 , C07C217/72 , C07C233/18 , C07C233/47 , C07C323/32 , C07C323/62 , C07C2601/02 , C07D207/333 , C07D213/38 , C07D233/64 , C07D239/26 , C07D263/32 , C07D277/24 , C07D277/26 , C07D277/28 , C07D307/38 , C07D307/42
摘要： Disclosed are immune-modulators of formula (I), the preparation method thereof, a pharmaceutical composition containing the immune-modulators, and the use of the pharmaceutical composition as a drug, especially as an immune-modulating drug. The compound can be used in immune disorders and immune suppression, and can be used in treating hypo-immunity, rejection after organ transplantation and auto-immune disease.
-
2.发明公开THE USE OF POTASSIUM 2-( - HYDROXYPENTYL) BENZOATE IN THE MANUFACTURE OF MEDICAMENTS FOR PREVENTING AND/OR TREATING SENILE DEMENTIA 有权钾的2-（羟基戊基）苯甲酸酯在药物方面的制造用于预防和/或治疗AGE性痴呆
公开(公告)号：EP2332530A4
公开(公告)日：2012-02-01
申请号：EP08773142
申请日：2008-07-08
发明人： WANG XIAOLIANG , ZHAO WANHONG , YANG JINGHUA , WANG LING , LI JIANG , XU SHAOFENG , FENG NAN , MA SHIPING
CPC分类号： A61K31/192
-
3.发明公开THE USE OF THE EFFECTIVE SECTION OF ALKALOIDS FROM RAMULUS MORI FOR PREPARATION OF A HYPOGLYCEMIG AGENT 审中-公开用于制备降血糖剂，从桑枝生物碱的截面的有效使用
公开(公告)号：EP2255822A4
公开(公告)日：2011-05-11
申请号：EP07800760
申请日：2007-08-22
发明人： LIU YULING , SHEN ZHUFANG , CHEN ZHEN , WANG RENYUN , XIA XUEJUN , CHEN YUETENG , LIU QUAN , SUN SUJUAN , XIE MINGZHI
IPC分类号： A61K36/605 , A61K125/00 , A61P3/10
CPC分类号： A61K36/605
摘要： The present invention relates to an effective fraction of alkaloids and the effective fraction is prepared from mulberry twig and its active ingredients are a composition of alkaloids. Determined by HPLC, the percentage of the total alkaloids are 50% or more by weight in the effective fraction and the percentage of the compound 1-deoxynojirimycin is 30% or more by weight in the total alkaloids. The effective fraction of the invention is prepared as the following steps: the mulberry twig is extracted by solvents, and the extract is precipitated by alcohol precipitation or flocculation to remove the impurities, and then concentrated, purified by resin chromatography. The present invention also relates to a pharmaceutical composition containing the said effective fraction of alkaloids and to the use of the effective fraction of alkaloids according to claim 1-4 in preparing hypoglycemic agents.
-
4.发明公开SUBMICRO EMULSION OF PACLITAXEL USING STEROID COMPLEX AS INTERMEDIATE CARRIER 审中-公开紫杉醇与类固醇复杂得多，运营商之间的亚微米乳液。
公开(公告)号：EP2494957A4
公开(公告)日：2014-04-16
申请号：EP10826102
申请日：2010-10-28
发明人： LIU YULING , XIA XUEJUN , GUO RUIFANG , ZHANG PENGXIAO , HAN RUI , FU ZHAODI , ZHOU CUIPING , WANG RENYUN , JIN DUJIA
IPC分类号： A61K9/107 , A61K31/337 , A61K47/28 , A61K47/44 , A61P35/00
CPC分类号： A61K9/1075 , A61K9/0019 , A61K31/337 , A61K47/28 , A61K47/44
摘要： A submicron emulsion of paclitaxel, the preparation method and the use thereof are disclosed. Said paclitaxel submicron emulsion comprises paclitarxel/steroid complex, oil for injection, water for injection, emulsifier, assistant emulsifier and isotonic agent, wherein the mole ratio of paclitaxel to steroid in the complex is 1:0.2ˆ¼4; preferably 1:0.25-2. Said submicron emulsion is useful for the treatment for malignant tumor. The average particle diameter of the submicron emulsion is less than 400 nm and the pH Value is 3.5-6.
-
5.发明公开SALTS OF 13A-(S)DESOXYTYLOPHORININE, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 有权13A（S）DESOXYTYLPHORININ，生产方法中的盐和其用途以及其药物组合物
公开(公告)号：EP2452681A4
公开(公告)日：2012-12-19
申请号：EP10796739
申请日：2010-07-09
发明人： YU SHISHAN , CHEN XIAOGUANG , LV HAINING , LI YAN , XU SONG , MA SHUANGGANG , LIU ZHENJIA , ZHANG YI , HU JINPING
IPC分类号： A61K31/437 , A61K9/00 , A61K9/08 , A61K9/16 , A61K9/20 , A61K9/48 , A61P29/00 , A61P35/00 , A61P35/04 , C07D471/04
CPC分类号： A61K31/437 , A61K9/08 , C07D471/04
-
6.发明公开TRIACETYL-3-HYDROXYPHENYLADENOSINE AND ITS USE FOR REGULATING BLOOD FAT 有权三乙酰-3- HYDROXYPHENYLADENOSIN及其用于控制血糖的黄油
公开(公告)号：EP2407474A4
公开(公告)日：2012-07-11
申请号：EP09818750
申请日：2009-03-10
IPC分类号： C07H19/16 , A61K31/7076 , A61P3/06
CPC分类号： A61K31/7076 , C07H19/167
-
7.发明公开CEPHALOMANNINE DERIVATIVES AND THEIR PREPARATION, MEDICINAL COMPOSITION AND USE 审中-公开CEPHALOMANNINDERIVATE及其制造药物组合物及其应用
公开(公告)号：EP2213667A4
公开(公告)日：2011-11-16
申请号：EP07816841
申请日：2007-11-15
发明人： FANG WEISHUO , CHEN XIAOGUANG , YANG CHUNGANG , LI XUAN , WANG HONGBO , LIU HONGYAN , HAN RUI , ZHAO LIMIN
IPC分类号： C07D305/14 , A61K31/337 , A61P35/00
CPC分类号： C07D305/14
-
公开(公告)号：EP2494956A4
公开(公告)日：2013-10-23
申请号：EP10826098
申请日：2010-10-28
发明人： LIU YULING , XIA XUEJUN , GUO RUIFANG , ZHANG PENGXIAO , ZHOU CUIPING , WANG RENYUN , JIN DUJIA
IPC分类号： A61K9/107 , A61K31/337 , A61K47/28 , A61P35/00
CPC分类号： A61K31/575 , A61K9/1075 , A61K9/145 , A61K9/19 , A61K9/2018 , A61K9/2054 , A61K9/4858 , A61K31/337 , A61K31/57 , A61K45/06 , A61K2300/00
-
9.发明公开N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF 审中-公开N6-取代腺苷衍生物，N6 - 取代腺嘌呤及其用途
公开(公告)号：EP2511283A4
公开(公告)日：2013-07-03
申请号：EP09851974
申请日：2009-12-10
发明人： SHI JIANGONG , ZHANG JIANJUN , YUE ZHENGGANG , LI MIN , ZHU CHENGGEN , ZHANG YING , ZI JIACHEN , WANG YAFANG , FAN XIAONA , XU RUIMING , LIN SHENG , LI YAN , YANG YONGCHUN , SHENG LI
IPC分类号： C07H19/167 , A61K31/70 , A61P25/08 , A61P25/16 , A61P25/20 , A61P25/28 , C07D473/00
CPC分类号： C07D473/34 , C07H19/167
摘要： The present invention provides N 6 -substituted adenosine derivatives and N 6 -substituted adenine derivatives, manufacturing methods thereof, a pharmaceutical composition comprising the said compounds above, and uses of of these compounds in manufacturing medicaments and health-care products for treating insomnia, convulsion, epilepsy, and Parkinson's diseases, and preventing and treating dementia.
-
10.发明公开TWO TYPES OF CRYSTALLINE OF PINOCEMBRIN: A AND B, THEIR PREPARATION AND THEIR USE FOR MANUFACTURE OF PHARMACEUTICAL COMPOSITIONS 有权TWO松属素晶体的类型：A和B，用于制造药物组合物的生产和使用
公开(公告)号：EP2360152A4
公开(公告)日：2012-05-30
申请号：EP08878072
申请日：2008-11-13
发明人： DU GUANHUA , LV YANG , WU SONG , WANG KE , CHANG YING , YANG ZHIHONG , TONG YUANFENG , GAO MEI
IPC分类号： C07D311/22 , A61K31/353 , A61P9/10 , C07D311/32
CPC分类号： C07D311/22 , A61K31/353 , C07D403/04 , C07D403/08
-
-
-
-
-
-
-
-
-
搜索结果
23 条记录 (耗时 0.01 秒)
