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公开(公告)号：EP3328359A2
公开(公告)日：2018-06-06
申请号：EP16833608.9
申请日：2016-07-29
申请人： NanoBio Corporation
发明人： SUTCLIFFE, Joyce , CIOTTI, Susan , BAKER, James R.
IPC分类号： A61K9/107 , A61K9/00 , A61K47/22 , A61K47/16 , A61K47/18 , A61K31/327 , A61K31/60 , A61K31/07
CPC分类号： A61K9/1075 , A61K9/0014 , A61K31/14 , A61K31/4425 , A61K47/183 , A61K47/186 , A61K2300/00
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公开(公告)号：EP3488863A1
公开(公告)日：2019-05-29
申请号：EP18192928.2
申请日：2012-09-10
申请人： Nanobio Corporation
发明人： BITKO, Vira , HAMOUDA, Tarek , FATTOM, Ali, I. , BAKER, James, R.
IPC分类号： A61K39/155 , A61K47/10 , A61K47/26 , A61K47/44 , A61K47/18 , A61K9/107 , A61K39/00 , A61K39/12
摘要： The present application relates to the field of immunology, in particular, a vaccine composition of respiratory syncytial virus (RSV) surface proteins, Fusion (F) and Glycoprotein (G) proteins subunit vaccine preferentially mixed with the immune cell targeting and enhancer, nanoemulsion to induce a protective immune response and avoid vaccine-induce disease enhancement.
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公开(公告)号：EP3454891A1
公开(公告)日：2019-03-20
申请号：EP17796763.5
申请日：2017-05-10
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4.发明公开HUMAN RESPIRATORY SYNCYTIAL VIRUS VACCINE 审中-公开IMPFSTOFF GEGEN HUMANES RESPIRATORISCHES SYNZYTIALVIRUS
公开(公告)号：EP2729169A1
公开(公告)日：2014-05-14
申请号：EP12735418.1
申请日：2012-07-06
申请人： Nanobio Corporation , Hamouda, Tarek , Bitko, Vira
IPC分类号： A61K39/155 , B82Y99/00
CPC分类号： A61K39/12 , A61K9/0019 , A61K9/06 , A61K9/1075 , A61K9/1271 , A61K9/5115 , A61K31/716 , A61K31/722 , A61K47/26 , A61K47/38 , A61K47/44 , A61K2039/5252 , A61K2039/543 , A61K2039/55555 , A61K2039/55566 , A61K2039/55583 , C07K16/1027 , C07K2317/33 , C07K2317/76 , C12N7/00 , C12N2760/18521 , C12N2760/18522 , C12N2760/18534 , A61K2300/00
摘要： The present invention relates to RSV vaccines and methods for inducing an immune response to RSV in a subject comprising administering an RSV vaccine.
摘要翻译： 本发明涉及RSV疫苗和在受试者中诱导针对RSV的免疫应答的方法，包括施用RSV疫苗。
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公开(公告)号：EP2588135A2
公开(公告)日：2013-05-08
申请号：EP11801436.4
申请日：2011-06-30
IPC分类号： A61K39/145 , A61K47/48 , A61K9/10 , A61K9/107 , A61P31/00
CPC分类号： A61K9/1075 , A61K39/39 , A61K2039/55566 , C12N2760/16134 , Y02A50/394 , Y02A50/403 , Y02A50/469
摘要： The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides nanoemulsion compositions harboring one or more immunogens within the oil phase of the nanoemulsion and methods of using the same for the induction of immune responses (e.g., innate and/or adaptive immune responses (e.g., for generation of host immunity against an environmental pathogen)). Compositions and methods of the invention find use in, among other things, clinical (e.g., therapeutic and preventative medicine (e.g., vaccination)) and research applications.
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公开(公告)号：EP3329936A1
公开(公告)日：2018-06-06
申请号：EP17209096.1
申请日：2012-08-22
申请人： Nanobio Corporation
发明人： FATTOM, Ali, I. , SIMON, Jakub , BAKER, James, R.
IPC分类号： A61K39/21
CPC分类号： A61K39/245 , A61K9/1075 , A61K39/12 , A61K39/39 , A61K2039/55555 , A61K2039/55566 , C12N2710/16634
摘要： The present application relates to the field of human immunology, in particular, a herpes simplex virus (HSV) vaccine. The subunit vaccine composition comprises isolated surface glycoproteins from herpes simplex viruses, fusion proteins or fragments thereof mixed in varied combination with a nanoemulsion, which is a potent immune enhancer.
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公开(公告)号：EP2278997B1
公开(公告)日：2016-08-10
申请号：EP09734640.7
申请日：2009-04-21
申请人： Nanobio Corporation
IPC分类号： A61K39/145 , A61K39/00 , A61L2/00
CPC分类号： A61K39/145 , A61K9/0014 , A61K9/0043 , A61K9/1075 , A61K39/00 , A61K39/12 , A61K39/39 , A61K2039/5252 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55566 , A61K2039/58 , A61K2039/70 , C07K14/005 , C12N7/00 , C12N2760/16134 , C12N2760/16171 , C12N2760/16234 , C12N2760/16271
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公开(公告)号：EP2747779A1
公开(公告)日：2014-07-02
申请号：EP12825300.2
申请日：2012-08-22
申请人： Nanobio Corporation
发明人： FATTOM, Ali, I. , SIMON, Jakub , BAKER, James, R.
IPC分类号： A61K39/21
CPC分类号： A61K39/245 , A61K9/1075 , A61K39/12 , A61K39/39 , A61K2039/55555 , A61K2039/55566 , C12N2710/16634
摘要： The present application relates to the field of human immunology, in particular, a herpes simplex virus (HSV) vaccine. The subunit vaccine composition comprises isolated surface glycoproteins from herpes simplex viruses, fusion proteins or fragments thereof mixed in varied combination with a nanoemulsion, which is a potent immune enhancer.
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9.发明公开COMPOSITIONS FOR INACTIVATING PATHOGENIC MICROORGANISMS, METHODS OF MAKING THE COMPOSITIONS, AND METHODS OF USE THEREOF 审中-公开灭活的病原微生物，方法组合物及其制造使用的成分和方法
公开(公告)号：EP1633322A2
公开(公告)日：2006-03-15
申请号：EP04809431.2
申请日：2004-06-03
申请人： Nanobio Corporation
发明人： BAKER, James, R. , ANNIS, Ted, C. , HAMOUDA, Tarek
IPC分类号： A61K9/00
CPC分类号： A61K31/7048 , A61K9/1075
摘要： Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.
摘要翻译： 纳米乳液组合物具有低毒性没表现出微生物或预防疾病的广谱失活中描述。 所述纳米乳剂包含在wässrige相到油相，其包含油和有机溶剂的，和一种或多种表面活性剂。 因此，提供制备纳米乳剂和灭活病原微生物的方法。
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公开(公告)号：EP3319930A1
公开(公告)日：2018-05-16
申请号：EP16821925.1
申请日：2016-07-06
申请人： NanoBio Corporation
发明人： CIOTTI, Susan
CPC分类号： A61K9/08 , A61K9/0019 , A61K39/00 , A61K47/18 , A61K47/183 , A61K47/26
摘要： The present disclosure relates to buffer-stabilized protein compositions and methods of making the same. The disclosed compositions and methods provide a means of stabilizing and preserving proteins or peptides in such a way that the proteins or peptides maintain their native conformation and structure, maintain biological activity, and prevent aggregation.
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