-
1.发明公开
公开(公告)号：EP4436991A1
公开(公告)日：2024-10-02
申请号：EP22817378.7
申请日：2022-11-22
发明人： YADAV, Arunkumar , PANDYA, Kunal , TAILOR, Bhavna , PATEL, Brijesh , JOSHI, Jigar , PATEL, Vipulkumar , PRASAD, Mohan
IPC分类号： C07K14/575 , A61K38/00 , C07C233/47 , C07K1/04 , C07K14/00 , C07K14/605
CPC分类号： C07K14/001 , C07K14/575 , A61K38/00 , C07K14/605 , A61K47/60 , A61K47/542
-
公开(公告)号：EP4410312A2
公开(公告)日：2024-08-07
申请号：EP24169238.3
申请日：2017-02-28
IPC分类号： A61K47/44
CPC分类号： A61K9/0048 , A61K47/10 , A61K9/107 , A61K47/44 , A61K31/202 , A61K38/13 , A61P27/02
摘要： Provided herein are formulations for topical ophthalmic formulations containing 0.087-0.093 wt % of cyclosporine, and methods of making and using such formulations. In some aspects and embodiments the formulations may include a polyoxyl lipid or fatty acid, and/or a polyalkoxylated alcohol and may include nanomicelles. Also included herein are methods of treating or preventing diseases or conditions, such as ocular diseases or conditions.
-
公开(公告)号：EP4368175A3
公开(公告)日：2024-07-17
申请号：EP24153550.9
申请日：2015-09-03
发明人： SAMARTH, Kumar , PRASHANT, Kane , BALARAM, Bhowmich Subhas , KIRTI, Ganorkar , NISHIT, Patel , ANILRAO, Dubewar Ashish , MUKESHBHAI, Patel Umeshkumar
CPC分类号： A61M5/14 , A61M5/1408 , A61J1/16 , A61K9/0019 , A61K47/26 , A61K31/4745 , G16Z99/00 , A61J1/10 , A61P35/00 , G16H20/17
摘要： The present invention relates to a method for enabling hospitals or clinics to administer a dose of a drug to patients in need thereof while avoiding steps of manipulation, dilution, reconstitution, dispensing, sterilization, transfer, handling or compounding before intravenous administration.
The present invention further relates to a perfusion system comprising different sets of perfusion containers, each container comprising a ready-to-infuse, stable, sterile, aqueous perfusion solution of a drug, wherein the set of perfusion containers alone or in combination provides for direct intravenous administration of a desired dose of the drug to a patient in need thereof, such that the delivered dose is equal to or within ± 5% of the calculated dose.-
-
公开(公告)号：EP2935216B1
公开(公告)日：2018-06-27
申请号：EP13828824.6
申请日：2013-12-17
IPC分类号： C07D213/74 , C07D471/04 , C07D211/56 , C07D213/61
CPC分类号： C07D487/04 , C07D211/56 , C07D213/61 , C07D213/74 , C07D471/04
摘要： The present invention provides compounds of Formula III and Formula VI, and processes for their preparation. The present invention further provides use of the compounds of Formula III and Formula VI for the preparation of tofacitinib or isomers or a mixture of isomers or salts thereof.
-
公开(公告)号：EP3288549A1
公开(公告)日：2018-03-07
申请号：EP16789380.9
申请日：2016-05-02
发明人： SINGH, Romi, Barat , RAMARAJU, Kalaiselvan , MONDAL, Balaram , KUMAR, Ashish , KAUSHIK, Suchitra
IPC分类号： A61K31/165 , A61K31/155
CPC分类号： A61J1/2093 , A61J1/1418 , A61J1/18 , A61J1/2006 , A61J1/2027 , A61K9/0095 , A61K9/10 , A61K9/145 , A61K9/5042 , A61K9/5047 , A61K9/5084 , A61K9/5089 , A61K31/155 , A61K31/165 , A61K31/43 , A61K31/4439 , A61K31/522 , A61K47/12
摘要： The present invention relates to oral liquid compositions of guanfacine. The liquid compositions can be immediate release or extended release compositions. The compositions comprise guanfacine in a concentration from about 0.1 mg/mL, to about 12.0 mg/mL of the composition. The liquid compositions can be in the form of ready-to use liquid compositions or reconstituted liquid compositions. It further relates to processes for the preparation of said oral liquid compositions.
-
公开(公告)号：EP3189045A2
公开(公告)日：2017-07-12
申请号：EP15832018.4
申请日：2015-08-10
发明人： THENNATI, Rajamannar , KILARU, Srinivasu , VALANCE SURENDRAKUMAR, Macwan , SHRIPRAKASH DHAR, Dwivedi
IPC分类号： C07D401/14
CPC分类号： C07D401/14 , C07B2200/13
摘要： The present invention provides novel salts of nilotinib and polymorphs thereof. The acid addition salts of nilotinib with benzenesulfonic acid, butanedisulfonic acid, 1-5-naphthalenedisulfonic acid, naphthalene-1-sulfonic acid and 1-hydroxynaph-thoic acid; hydrates and anhydrates thereof.
摘要翻译： 本发明提供了尼罗替尼及其多晶型物的新型盐。 尼罗替尼与苯磺酸，丁烷二磺酸，1-5-萘二磺酸，萘-1-磺酸和1-羟基萘甲酸的酸加成盐; 水合物和无水物。
-
公开(公告)号：EP3174878A1
公开(公告)日：2017-06-07
申请号：EP15826397.0
申请日：2015-07-21
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D239/42 , C07F7/1892
摘要： The present invention relates to a process for the preparation of palbociclib utilizing a silyl-protected crotonic acid derivative to produce a silyl-protected 2-chloro-4-(cyclopentylamino)-5-(1-methyl-2-carboxy-ethen-1-yl)pyrmidine followed by intramolecular cyclization of the pyrmidine intermediate to produce 2-chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one which is then converted to palbociclib.
摘要翻译： 本发明涉及一种利用甲硅烷基保护的巴豆酸衍生物制备palbociclib以制备甲硅烷基保护的5-（1-甲基-3-羧基 - 丙-1-烯-1-基）-2-氯 - 哌嗪，然后将化合物哌嗪中间体分子内环化生成2-氯-8-环戊基-5-甲基-8H-吡啶并[2,3-d]嘧啶-7-酮，然后将其转化为palbociclib。
-
公开(公告)号：EP1909770B1
公开(公告)日：2013-03-20
申请号：EP06780511.9
申请日：2006-02-22
IPC分类号： A61K9/20 , A61K31/4015
CPC分类号： A61K9/209 , A61K31/4015
-
10.发明公开METERED DROP BOTTLE FOR DISPENSING MICROLITER AMOUNTS OF A LIQUID IN THE FORM OF A DROP 有权WITH DROP DIMENSION瓶问题FORM A液滴微升表示的数额
公开(公告)号：EP2089282A2
公开(公告)日：2009-08-19
申请号：EP07870537.3
申请日：2007-12-07
CPC分类号： B65D47/18 , A61F9/0008 , A61F9/0026 , B65D1/32
摘要： The present invention relates to a metered drop bottle (4), for dispensing microliter amounts of a liquid in the form of a drop comprising: (a) a bottle (4) with a flexible portion on the walls to decrease the internal volume by a fixed volume; (b) a plunger (6) with a fixed stroke for depressing the flexible portion of the walls of the bottle (4), and (c) a nozzle tip (2) having an internal and/or outer diameter no more than 1.2 mm.
-
-
-
-
-
-
-
-
-
搜索结果
74 条记录 (耗时 0.022 秒)
