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公开(公告)号：EP2894163A4
公开(公告)日：2016-04-20
申请号：EP12749806
申请日：2012-02-08
发明人： GONG MIN , FU GANG , XU WEIREN , TANG LIDA , REN XIAOWEN , LIU PENG , WANG YULI , WU JIANG , ZOU MEIXIANG
CPC分类号： C07K14/605 , A61K38/00
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2.发明公开
公开(公告)号：EP1935892A4
公开(公告)日：2009-04-01
申请号：EP06791264
申请日：2006-10-16
发明人： WANG JIANWU , XU WEIREN , YONG JIANPING , TANG LIDA , ZHANG SHIJUN , LIU LIJUN , WANG YULI , REN XIAOWEN
IPC分类号： A61P1/16 , A61K31/415 , A61P11/14 , A61P25/04 , A61P31/12 , A61P37/08 , C07D261/08 , C07D413/04
CPC分类号： C07D261/08 , A61K31/415 , C07D413/04
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3.发明公开PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF 有权WITH A DEOXYGLUCOSESTRUKTUR，工艺苯基-C葡萄糖苷衍生物及其制造和使用
公开(公告)号：EP2933250A4
公开(公告)日：2016-01-20
申请号：EP13864482
申请日：2013-12-05
发明人： ZHAO GUILONG , WANG YULI , LIU BINGNI , XIE YAFEI , LIU YUQIANG , LIU PENG , WU JIANG , HOU JIAJIA , WEI WEI , DU WEN , XU WEIREN , TANG LIDA , ZOU MEIXIANG
IPC分类号： C07D309/10 , A61K31/351 , A61K31/381 , A61K31/382 , A61K31/7048 , A61P3/10 , C07D335/02 , C07D407/12 , C07D409/10 , C07D493/08 , C07D493/10 , C07H1/00 , C07H9/04 , C07H19/01
CPC分类号： C07H19/01 , A61K47/22 , C07D309/06 , C07D309/10 , C07D335/02 , C07D407/12 , C07D409/10 , C07D493/08 , C07D493/10
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4.发明公开CYCLOASTRAGENOL MONOGLUCOSIDE, PREPARATION, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF 审中-公开Cycloastragenol - 葡萄糖甙，生产，药物组合物及其用途
公开(公告)号：EP2199402A4
公开(公告)日：2011-07-06
申请号：EP08783682
申请日：2008-09-08
发明人： HAN YINGMEI , XIA GUANGPING , XU WEIREN , ZHAO ZHUANYOU , LIU WULIN , ZHAO NAXIA , LIU PENG , ZHANG SHIJUN , WANG YULI , WANG WEITING , TANG LIDA , FU XIAOLI
IPC分类号： C12P19/56 , A61K9/00 , A61K9/08 , A61K9/12 , A61K9/19 , A61K31/7048 , A61K36/481 , A61P9/00 , C07H17/04
CPC分类号： A61K36/481 , A61K31/7048 , C07J17/005 , C12P19/56
摘要： This invention provides a method for preparing cycloastragenol monoglucoside CMG (cydoastragenol-6-O-²-D-glucoside), comprising the steps of: a. using astragaloside IV or Astragali extracts prepared by a conventional method as raw materials and adding an appropriate solvent thereinto to form a raw material solution; b. adding hydrolase and allowing for hydrolysis at a constant temperature to obtain a hydrolysate; c. separating the hydrolysate with macroporous adsorption resin; and d. obtaining the product by purification and separation. The present invention further provides cycloastragenol-6-O-²-D-glucoside prepared according to the method of this invention as well as its use in the preparation of a medicament for treating cardiovascular diseases and pharmaceutical compositions comprising the same.
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5.发明公开THIENOPYRIDINE ESTER DERIVATIVE CONTAINING NITRILE, PREPARATION METHOD, USE AND COMPOSITION THEREOF 有权THIENOPYRIDINESTER衍生腈，工艺制作，它们的用途及其组合物
公开(公告)号：EP2570417A4
公开(公告)日：2013-09-04
申请号：EP11780039
申请日：2011-03-23
发明人： LIU DENGKE , LIU YING , YUE NAN , CHEN FURONG , TAN CHUBING , ZHOU YUNSONG , LIU PENG , ZHAO YIGUI , ZHI DEGUANG , LIU MO , LIU BINGNI , HUANG CHANGJIANG , TANG LIDA
IPC分类号： C07D495/04 , A61K31/4365 , A61P7/02 , A61P9/00 , A61P9/10
CPC分类号： C07D495/04 , A61K9/0019 , A61K9/1652 , A61K9/19 , A61K9/2054 , A61K9/2059 , A61K47/10 , A61K47/26
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6.发明公开
公开(公告)号：EP2530079A4
公开(公告)日：2013-06-19
申请号：EP11736592
申请日：2011-01-14
发明人： ZHAO GUILONG , SHAO HUA , XU WEIREN , LIU WEI , WANG YULI , TANG LIDA , TAN CHUBING , LIU BINGNI , ZHANG SHIJUN
IPC分类号： C07D309/10 , A61K31/351 , A61K31/70 , A61P3/10 , C07D409/10 , C07H7/04
CPC分类号： C07H7/04 , A61K31/351 , A61K31/70 , C07D309/10 , C07D409/10 , C07H7/06
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7.发明公开
公开(公告)号：EP2404909A4
公开(公告)日：2012-05-16
申请号：EP09832806
申请日：2009-11-30
发明人： ZHAO GUILONG , XU WEIREN , WANG YULI , TANG LIDA , LI YILIANG , ZOU MEIXIANG , LIU WEI , SHAO HUA , TAN CHUBING , LIU PENG
IPC分类号： C07D277/46 , A61K31/426 , A61K31/427 , A61P3/10 , C07D277/58 , C07D417/12
CPC分类号： C07D277/46 , C07D277/58 , C07D417/12
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