摘要:
A method of interrogating a WDM optical communication system is provided to obtain one or more performance parameters. In accordance with the method, an optical probe wavelength is generated and possibly modulated in a prescribed manner. The probe signal is transmitted along a selected optical path through the WDM optical communication system for a duration of time that is less than a response time of network elements that impact signal quality along the selected optical path.
摘要:
Systems, methods, and software products analyze healthcare data. First input data is collected from a first source and second input data is collected from a second source disparate from the first source. The second source has a data format that is different from a format of the first source. The first input data is processed to determine a first concept and the second input data is processed to determine a second concept. A relationship between the first and second concepts is determined. The first and second concepts are stored within a knowledgebase based upon the relationship and a patient medical model is generated from the knowledgebase.
摘要:
A method for transmitting data over an optical communication system is performed by sequentially tuning a laser beam among a plurality of optical wavelengths. At least one data signal is modulated onto the plurality of optical wavelengths by sequentially switching the modulation of the data signal among the plurality of optical wavelengths such that at any given time the data signal is only modulated onto a single one of the optical wavelengths. The sequential switching is performed at a rate equal to or greater than a response time of one or more optical amplifiers used for amplifying the optical wavelengths.
摘要:
Electronic devices and systems that overcome the limitation of stiffness and rigidity generally associated with electronics and allow for delivery via minimally invasive or percutaneous access and delivery systems are described herein. The devices and systems are able to change in size, such as from a larger electronic construct to a smaller flowable configuration. The devices and systems are configured to open or reconfigure to return to the original size and spatial dimensions at the site. In another embodiment, the devices and systems begin as a plurality of discrete electrical elements in a flowable state, and change to a non-fluent state thereby forming an electrical construct. The electrical elements are able to communicate by direct contact with each other or near field inter-device communication means. This allows the electronic device or system to be applied, adhere and conform to the underlying surface.
摘要:
T-lymphocyte invasion and metastases (Tiam-1) has been identified as a marker and anti-cancer drug target for therapy of metastatic bone cancer in individuals afflicted with prostate cancer. The present disclosure provides methods and compounds for inhibiting metastases by disrupting Tiam-1 expression and activity. One particularly preferred compound comprises a disulfomanide of the formula.
摘要:
A glycosylated pleiotropic peptide pituitary adenylate cyclase-activating polypeptide (PACAP) which can both agonize PAC1 receptors, causing neuroprotective effects, and antagonize VPAC receptors, causing anti-inflammation in several models of acute neuronal damage and neurodegenerative diseases, including ALS, PD, migraines, and certain forms of dementia, is described. Also described is a method of relieving symptoms of ALS, PD, migraines, and certain forms of dementia, comprising administering to a subject in need thereof an effective amount of a glycosylated PACAP.