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1.发明授权IN VITRO AND IN VIVO DELIVERY OF GENES AND PROTEINS USING THE BACTERIOPHAGE T4 DNA PACKAGING MACHINE 有权使用噬菌体T4 DNA包装机进行基因和蛋白质的体内和体内递送
公开(公告)号：EP2964770B1
公开(公告)日：2017-06-14
申请号：EP14760017.5
申请日：2014-01-31
发明人： RAO, Venigalla
CPC分类号： C12N15/87 , C07K2319/10 , C07K2319/40 , C07K2319/61 , C12N2795/10122 , C12N2795/10123 , C12N2795/10142 , C12N2810/6009 , C12N2810/85 , C12N2810/859
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公开(公告)号：EP2970003A1
公开(公告)日：2016-01-20
申请号：EP14762280.7
申请日：2014-03-10
发明人： GONG, Weiliang , LUTZE, Werner , PEGG, Ian L.
CPC分类号： C04B38/02 , C04B28/006 , Y02P40/165 , Y02W30/92 , Y02W30/94 , Y02W30/95 , C04B12/04 , C04B14/06 , C04B14/106 , C04B14/28 , C04B14/303 , C04B18/08 , C04B18/141 , C04B18/162 , C04B20/002 , C04B20/0048 , C04B20/008 , C04B22/04 , C04B22/06 , C04B38/08 , C04B2103/0088 , C04B2103/22 , C04B2103/58
摘要： A composite binder comprises: one or more Class F fly ash materials, one or more gelation enhancers, and one or more hardening enhancers, wherein each of the one or more Class F fly ash materials comprises 15 wt. % or less calcium oxide, and wherein the composite binder is a Portland cement-free binder for concrete. Also provided are Geopolymer Composite Cellular Concretes (GCCCs) including the composite binder and methods of making these GCCCs.
摘要翻译： 复合粘合剂包含：一种或多种F类飞灰材料，一种或多种胶凝增强剂和一种或多种硬化增强剂，其中一种或多种F类飞灰材料中的每一种包含15重量％或更少的氧化钙，以及 其中所述复合粘结剂是用于混凝土的无波特兰水泥粘结剂。 还提供了包括复合粘合剂的Geopolymer复合细胞混凝土（GCCC）以及制造这些GCCC的方法。
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公开(公告)号：EP1904175B1
公开(公告)日：2011-04-13
申请号：EP01903281.2
申请日：2001-01-25
摘要： Apparatus for establishing a region of bio-effectiveness in a human or animal body, comprising: means for generating a first EM field encompassing in part a body region, means for generating one additional EM field, means for modulating the first and the additional fields to cause them to be at a first magnitude for a first period of time and at a second magnitude for a following period of time, whith changes occurring within 10 second intervals, and means for controlling said modulation means to cause the magnitude of the first EM field and the magnitude of the additional field to be complementary, whereby within said region the respective fields will provide a combined field having a predetermined pattern of limited differences in magnitudes but outside the region the respective fields will alternate between said first and second magnitudes.
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公开(公告)号：EP2198919A1
公开(公告)日：2010-06-23
申请号：EP10158869.7
申请日：2001-01-25
摘要： The invention relates to a method of targeting and enhancing therapeutic or palliative treatments by exposing cells, tissues or organs to EM fields (10Hz - 5GHz) thereby enhancing the endogenous cellular protective responses of normal tissues and/or suppress the endogenous cellular protective responses of diseased tissues.
摘要翻译： 本发明涉及通过将细胞，组织或器官暴露于EM场（10Hz-5GHz）从而增强正常组织的内源细胞保护性应答和/或抑制患病的内源性细胞保护性应答来靶向和增强治疗或姑息性治疗的方法 组织。
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公开(公告)号：EP1904175A1
公开(公告)日：2008-04-02
申请号：EP01903281.2
申请日：2001-01-25
摘要： Apparatus for establishing a region of bio-effectiveness in a human or animal body, comprising: means for generating a first EM field encompassing in part a body region, means for generating one additional EM field, means for modulating the first and the additional fields to cause them to be at a first magnitude for a first period of time and at a second magnitude for a following period of time, whith changes occurring within 10 second intervals, and means for controlling said modulation means to cause the magnitude of the first EM field and the magnitude of the additional field to be complementary, whereby within said region the respective fields will provide a combined field having a predetermined pattern of limited differences in magnitudes but outside the region the respective fields will alternate between said first and second magnitudes.
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6.发明公开
公开(公告)号：EP3458981A1
公开(公告)日：2019-03-27
申请号：EP17800253.1
申请日：2017-05-19
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公开(公告)号：EP2542681B1
公开(公告)日：2019-02-27
申请号：EP11765160.4
申请日：2011-04-08
发明人： RAO, Venigalla
IPC分类号： C12N15/63 , C12N7/01 , A61K31/7088 , A61K31/00 , A61K39/00 , A61K31/711 , C07K14/005
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8.发明公开IN VITRO AND IN VIVO DELIVERY OF GENES AND PROTEINS USING THE BACTERIOPHAGE T4 DNA PACKAGING MACHINE 有权在体外和基因和蛋白质BY噬菌体T4 DNA封装机体内释放
公开(公告)号：EP2964770A1
公开(公告)日：2016-01-13
申请号：EP14760017.5
申请日：2014-01-31
发明人： RAO, Venigalla
CPC分类号： C12N15/87 , C07K2319/10 , C07K2319/40 , C07K2319/61 , C12N2795/10122 , C12N2795/10123 , C12N2795/10142 , C12N2810/6009 , C12N2810/85 , C12N2810/859
摘要： Described is T4 DNA packaging machine comprising: one or more DNA molecules packaged in a head of the T4 DNA packaging machine, one or more Hoc-fused proteins displayed on the head of the T4 DNA packaging machine, and one or more Soc-fused proteins displayed on the head of the T4 DNA packaging machine. Also described are methods of making and using such a T4 DNA packaging machine.
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9.发明公开Method for making an immunogenic composition with Hoc fusion proteins and/or Soc fusion proteins 审中-公开一种用于通过使用融合蛋白Hoc和/或Soc融合蛋白的制备免疫原性组合物的方法
公开(公告)号：EP2196214A1
公开(公告)日：2010-06-16
申请号：EP10158774.9
申请日：2004-12-17
CPC分类号： C12N7/00 , A61K39/07 , A61K39/12 , A61K39/21 , A61K39/295 , A61K2039/5256 , A61K2039/55505 , A61K2039/57 , A61K2039/6075 , A61K2039/627 , A61K2039/64 , A61K2039/645 , A61K2039/70 , C07K14/005 , C07K2299/00 , C07K2319/00 , C07K2319/21 , C07K2319/735 , C12N15/1037 , C12N15/86 , C12N2740/16034 , C12N2740/16222 , C12N2740/16234 , C12N2740/16322 , C12N2740/16334 , C12N2795/10121 , C12N2795/10143 , C40B40/02
摘要： The invention relates to methods for making an immunogenic composition that employs Hoc and/or Soc fusion protein and T4 bacteriophage particle.
摘要翻译： 本发明涉及一种用于制备免疫原性组合物的方法没有采用Hoc和/或Soc融合蛋白和T4噬菌体粒子。
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公开(公告)号：EP0567590A1
公开(公告)日：1993-11-03
申请号：EP92905377.0
申请日：1992-01-16
摘要： Agencement servant à inhiber les effets adverses, sur un organisme vivant, d'un champ ambiant variable dans le temps, qui présente une composante électrique égale ou inférieure à 5 Kv/M, et/ou une composante magnétique égale ou inférieure à 500 muT. Afin de conférer une protection à cet organisme, au moins l'un des paramètres caractéristiques dudit champ auquel est exposé cet organisme vivant, est modifié à des intervalles de temps inférieurs à 10 secondes.
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