摘要:
Embodiments described herein include devices, systems, and methods for reducing the distance between two locations in tissue. In one embodiment, an anchor may reside within the right ventricle in engagement with the septum. A tension member may extend from that anchor through the septum and an exterior wall of the left ventricle to a second anchor disposed along a surface of the heart. Perforating the exterior wall and the septum from an epicardial approach can provide control over the reshaping of the ventricular chamber. Guiding deployment of the implant from along the epicardial access path and another access path into and through the right ventricle provides control over the movement of the anchor within the ventricle. The joined epicardial pathway and right atrial pathway allows the tension member to be advanced into the heart through the right atrium and pulled into engagement along the epicardial access path.
摘要:
Apparatus for securing a first object to a second object, including an elongated body having a lumen extending between distal and proximal ends, the lumen comprising distal and proximal sections, the distal section having a wider diameter than the proximal section; a window extending through the side wall of the elongated body, in the vicinity of the intersection between the distal and proximal sections, and communicating with the lumen; an elongated element comprising proximal and distal ends and extending through the lumen; and a locking element mounted to the distal end of the elongated element and disposed in the distal section; whereby, when the elongated body is disposed in a second object, and a first object extends through the window, proximal movement of the locking element causes the elongated body to capture the first object to the elongated body, whereby to secure the first object to the second object.
摘要:
Apparatus for securing a first object to a second object, the apparatus comprising: an elongated body having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end, the lumen comprising a first section and a second section, the first section of the lumen being disposed distal to the second section of the lumen, and with the first section of the lumen having a wider diameter than the second section of the lumen; at least one longitudinally-extending slit extending through the side wall of the elongated body and communicating with the lumen, the at least one longitudinally-extending slit having a distal end and a proximal end, with the distal end of the at least one longitudinally-extending slit being spaced from the distal end of the elongated body; and an elongated element extending through the lumen of the elongated body.
摘要:
In order to anchor a suture in tissue, a device is proposed which has a guide sleeve, a sonotrode, an anchor, and the suture. The guide sleeve comprises a distal part having a smaller cross-section and a proximal part having a larger cross-section. The sonotrode extends in the lumen of the guide sleeve and comprises a distal end and a proximal end, wherein the proximal end is equipped for coupling the sonotrode to a vibration source (such as an ultrasonic device). The anchor is disposed at the distal end of the device and comprises an anchor base and an anchoring sleeve that rests on a shoulder of the anchor base. The anchoring sleeve has a material that can be liquefied by mechanical vibrations, or is made thereof. A central region of the suture runs through the anchor base, and two end regions of the suture are fastened to the guide sleeve. The anchoring sleeve is clamped, or disposed such that it can be clamped, between the anchor base and an impact sleeve, or the sonotrode, or the guide sleeve. The device is particularly suited for anchoring sutures in bone tissue.
摘要:
Methods and devices are disclosed for manipulating the tongue (9). An implant (3038) is positioned within at least a portion of the tongue (9) and may be secured to other surrounding structures such as the mandible (13) and/or hyoid bone (15). In general, the implant (3038) is manipulated to displace at least a portion of the posterior tongue in an anterior or lateral direction, or to alter the tissue tension or compliance of the tongue (9). Methods and devices for engaging the tongue (9) are also disclosed. One embodiment of a tongue remodeling system includes an elongate implant (3038) configured to be positioned within a selected region of the tongue (9) and a tether (3041) configured to suspend the tongue (9). The tether (3041) can be configured to be looped around the elongate implant (3038) and connected to another structure.
摘要:
Systems and methods for treating internal tissue defects, such as septal defects, with clip-based devices are provided. An exemplary clip-based device includes a tubular body having at least a first and a second deflectable member coupled thereto. The first and second members are coupled on opposite ends of the tubular body and configured to deflect between an undeployed configuration and a deployed configuration. In the deployed configuration, each member extends outwardly away from the tubular body in a position configured to abut a tissue surface. The first and second members are preferably configured to maintain a tissue wall therebetween and at least partially close any opening in the tissue wall.
摘要:
Methods and devices are disclosed for manipulating the tongue (9). An implant (500) is positioned within at least a portion of the tongue (9) and may be secured to other surrounding structures such as the mandible (13) and/or hyoid bone (15). In general, the implant (500) is manipulated to displace at least a portion of the posterior tongue (410) in an anterior or lateral direction, or to alter the tissue tension or compliance of the tongue (9). Methods and devices are also disclosed for manipulating other soft tissue structures, including the soft palate (4) and pharyngeal airway.
摘要:
A method for direct therapeutic treatment of myocardial tissue in a localized region of a heart having a pathological condition. The method includes identifying a target region of the myocardium and applying material directly and substantially only to at least a portion of the myocardial tissue of the target region. The material applied results in a physically modification the mechanical properties, including stiffness, of said tissue. Various devices and modes of practicing the method are disclosed for stiffening, restraining and constraining myocardial tissue for the treatment of conditions including myocardial infarction or mitral valve regurgitation.
摘要:
A device for establishing an anchorage in tissue with the aid of mechanical vibration and a material having thermoplastic properties and being liquefiable by the mechanical vibration is provided. The device comprises a vibrating element (51), comprising a distal portion (51.2) of a smaller cross section, a proximal portion (51.1) of a larger cross section and a shoulder (51.3) therebetween, a proximal end of the vibrating element being suitable for being coupled to a vibration source and the vibrating element being capable of transmitting vibration generated by the vibration source to a distal end of the vibrating element (3). Alternatively, the device comprises a separate guide element accommodated by an axial recess of the guide element and replacing the distal portion. The device further comprises a tube-shaped liquefiable part (50) comprising the liquefiable material and having an inner and an outer cross section, wherein the distal portion (51.2) of the vibrating element (51) or the guide element is dimensioned for extending into the tube-shaped liquefiable part (50), and wherein the liquefiable part (50) is fixed to the distal portion (51.2) of the vibrating element (51) or sits thereon.
摘要:
The invention relates to an anchor arrangement (2) for surgical tissue repair, such as in particular for repair of a meniscus tear (R), having at least one first anchor (4) and one second anchor (6), which are movable along a hollow needle (14) for placement on a tissue to be repaired (G) and connected to each other via a seam element (8). According to the invention, the first anchor (4) and the second anchor (6) each extend between a distal end (22) and a proximal end (24) and form a guide surface (26) on the outside thereof for contacting an inside (28) of a hollow needle (14) at least in part. In addition, there are deflection means (38) on the anchors (4, 6), via which a torque (MD) can be applied at least in part to the anchors (4, 6) during or after setting. According to the invention, at least one of the anchors (4, 6) has at least two anchor sections (50, 52), which are movable relative to each other and which can be pivoted relative to each other between a folded position, in which the guide surface (26) spans a cross-section (Q) deviating from a circular profile, and an unfolded position.