公开(公告)号：EP2623108B1

公开(公告)日：2017-09-27

申请号：EP10857921.0

申请日：2010-10-29

申请人： Korea Institute of Oriental Medicine

发明人： MA, Jin Yeul ,  CHUNG, Tae Ho ,  IM, Ga Young ,  KIM, Dong Seon ,  UM, Young Ran ,  EUM, Hyun Ae ,  LEE, Jae Hoon ,  CHOI, Sung Up ,  CHO, Byoung Heon

IPC分类号： A61K8/97 ,  A61Q19/00 ,  A23L33/105 ,  A61K36/78 ,  A61K36/808 ,  A61K36/23 ,  A61K36/232 ,  A61K36/25 ,  A61K36/258 ,  A61K36/28 ,  A61K36/296 ,  A61K36/355 ,  A61K36/484 ,  A61K36/489 ,  A61K36/634 ,  A61K36/725 ,  A61K36/238

CPC分类号： A61K36/258 ,  A23L33/105 ,  A61K8/97 ,  A61K36/23 ,  A61K36/232 ,  A61K36/238 ,  A61K36/25 ,  A61K36/28 ,  A61K36/296 ,  A61K36/355 ,  A61K36/484 ,  A61K36/489 ,  A61K36/634 ,  A61K36/725 ,  A61K36/78 ,  A61K36/808 ,  A61K2800/85 ,  A61Q19/00 ,  A61K2300/00

公开(公告)号：EP2623108A4

公开(公告)日：2014-03-12

申请号：EP10857921

申请日：2010-10-29

申请人： KOREA INST ORIENTAL MEDICINE

发明人： MA JIN YEUL ,  CHUNG TAE HO ,  IM GA YOUNG ,  KIM DONG SEON ,  UM YOUNG RAN ,  EUM HYUN AE ,  LEE JAE HOON ,  CHOI SUNG UP ,  CHO BYOUNG HEON

IPC分类号： A61K36/484 ,  A23L1/30 ,  A61K8/97 ,  A61K36/23 ,  A61K36/232 ,  A61K36/25 ,  A61K36/258 ,  A61K36/28 ,  A61K36/296 ,  A61K36/355 ,  A61K36/489 ,  A61K36/634 ,  A61K36/725 ,  A61K36/78 ,  A61K36/808 ,  A61P17/00 ,  A61Q19/00

CPC分类号： A61K36/258 ,  A23L33/105 ,  A61K8/97 ,  A61K36/23 ,  A61K36/232 ,  A61K36/238 ,  A61K36/25 ,  A61K36/28 ,  A61K36/296 ,  A61K36/355 ,  A61K36/484 ,  A61K36/489 ,  A61K36/634 ,  A61K36/725 ,  A61K36/78 ,  A61K36/808 ,  A61K2800/85 ,  A61Q19/00 ,  A61K2300/00

摘要： The present invention relates to a composition for preventing or treating atopic dermatitis, and more specifically to a pharmaceutical composition and a health supplement for preventing or treating atopic dermatitis, the composition and the supplement having as active ingredients extract of a galenical mixture including sophora root, licorice, lonicer aflower, Korean angelica root, Korean aralia root, saussurea root, seselos radix, zizyphus spinosi, Houttuynia cordata, forsythia fruit, lappa fruit, Epimedium koreanum Nakai, ginseng, lithospermum, oleoresin, cnidium, scorophulariae radix, and reynoutria, or lactobacillus fermentation of the galenical extract prepared by inoculating lactobacillus to the galenical extract and fermenting same. The galenical extract or the galenical extract fermentation of the present invention shows reduction in the number of scratching, a trend of decrease in clinical features of atopic symptoms such as erythema, itchiness and dry skin, edema and hematoma, erosion, and lichenification, and reduces the IgE concentration in blood, which is related to exogenous atopic dermatitis, among laboratory animal models having atopic dermatitis, and is thereby, useful for the prevention and/or treatment of atopic dermatitis.

摘要翻译： 本发明涉及一种组合物，用于预防或治疗特应性皮炎，并且更具体地涉及药物组合物和保健品用于预防或治疗特应性皮炎，组合物以及具有包含苦参盖仑混合物作为活性成分的提取物中的补充， 甘草，Lonicer aflower，韩语安热利卡·罗特，韩语龙牙根，雪莲根，seselos基数，枣斯皮诺西，蕺，连翘果实，牛蒡果，朝鲜淫羊藿，人参，紫草，油树脂，蛇床子，scorophulariae基数，和虎杖，或 通过接种乳酸菌于盖仑制剂提取物和发酵相同制备盖仑制剂提取物乳酸菌发酵。 盖仑制剂的提取物或本发明的盖仑制剂提取物发酵示出了划伤，在特应性症状临床特征降低的趋势的数量减少：如红斑，瘙痒和皮肤干燥，水肿和血肿，侵蚀和苔藓样硬化，并降低 IgE的浓度在血液，所有这与外源性过敏性皮炎，具有特应性皮炎的实验动物模型中，并且由此，对于特应性皮炎的预防和/或治疗是有用的。

公开(公告)号：EP3197458A1

公开(公告)日：2017-08-02

申请号：EP15788101.2

申请日：2015-09-22

申请人： Greenpharma S.A. ,  Centre National de la Recherche Scientifique (C.N.R.S.) ,  Université de Strasbourg

发明人： BERNARD, Philippe ,  ABBOUD, Dayana ,  GALZI, Jean-Luc ,  FROSSARD, Nelly ,  PILLARD, Christelle ,  DO, Quoc, Tuan

IPC分类号： A61K31/522 ,  A61P17/00 ,  A61P11/06 ,  A61P37/08

CPC分类号： A61K31/522 ,  A61K8/19 ,  A61K8/34 ,  A61K8/345 ,  A61K8/368 ,  A61K8/37 ,  A61K8/44 ,  A61K8/4913 ,  A61K8/4926 ,  A61K8/4953 ,  A61K8/60 ,  A61K8/64 ,  A61K8/678 ,  A61K8/922 ,  A61K8/97 ,  A61K9/0014 ,  A61K9/0053 ,  A61K9/06 ,  A61K31/045 ,  A61K31/047 ,  A61K31/192 ,  A61K31/198 ,  A61K31/231 ,  A61K31/355 ,  A61K31/4015 ,  A61K31/455 ,  A61K31/7004 ,  A61K31/7016 ,  A61K33/38 ,  A61K36/185 ,  A61K36/28 ,  A61K36/286 ,  A61K36/73 ,  A61K36/808 ,  A61K36/8998 ,  A61K38/018 ,  A61K45/06 ,  A61K47/14 ,  A61Q19/00 ,  A61K2300/00

摘要： The invention relates to the cosmetic or pharmaceutical use of a composition containing a derivative of theophylline of formula (I) that inhibits chemokines, in order to prevent or treat internal and/or external chronic inflammatory disorders. R represents an alkyl, cycloalkyl or alkenyl group in which at least one -CH
2 - group can be replaced by -O- or substituted by at least one radical selected from among the alkyl, hydroxy and alkoxy radicals.

摘要翻译： 本发明涉及包含抑制趋化因子的式（I）茶碱衍生物的组合物的美容或药物用途，以预防或治疗内部和/或外部慢性炎性病症。 R表示其中至少一个-CH 2 - 基团可被-O-代替或被至少一个选自烷基，羟基和烷氧基的基团取代的烷基，环烷基或烯基。

公开(公告)号：EP3076984A1

公开(公告)日：2016-10-12

申请号：EP13831835.7

申请日：2013-12-02

申请人： Sirbal Ltd.

发明人： SHRAIBOM, Nadav

IPC分类号： A61K36/804 ,  A61K36/355 ,  A61K36/708 ,  A61K36/808 ,  A61K36/11 ,  A61K36/284 ,  A61K36/286 ,  A61K36/30 ,  A61K36/315 ,  A61K36/54 ,  A61K36/65 ,  A61K36/73

CPC分类号： A61K36/708 ,  A61K36/11 ,  A61K36/284 ,  A61K36/286 ,  A61K36/30 ,  A61K36/315 ,  A61K36/355 ,  A61K36/54 ,  A61K36/65 ,  A61K36/73 ,  A61K36/804 ,  A61K36/808

摘要： A method and medicine for treating melanoma, BCC (basal cell carcinoma) or psoriasis or other inflammatory skin disease, or a combination thereof, comprising applying or injecting to an infected skin area of a patient diagnosed with melanoma, BCC (basal cell carcinoma) or psoriasis or other inflammatory skin disease, or a combination thereof, a treatment regimen that includes periodic doses of a molecular combination of emodin and digoxin and/or an herbal combination of Da Huang and Sheng Di Huang.

公开(公告)号：EP2709642A4

公开(公告)日：2015-08-26

申请号：EP12865478

申请日：2012-05-15

申请人： HAUS BIOCEUTICALS INC

发明人： YESUDAS TOMY ,  ALEX PHILIP ,  CENTOLA MICHAEL ,  PAYNE ADAM JOSHUA

IPC分类号： A61K36/185 ,  A61K36/22 ,  A61K36/23 ,  A61K36/27 ,  A61K36/28 ,  A61K36/29 ,  A61K36/31 ,  A61K36/35 ,  A61K36/48 ,  A61K36/66 ,  A61K36/68 ,  A61K36/71 ,  A61K36/76 ,  A61K36/77 ,  A61K36/808 ,  A61K36/899 ,  A61K36/90

CPC分类号： A61K36/90 ,  A61K36/185 ,  A61K36/22 ,  A61K36/23 ,  A61K36/24 ,  A61K36/27 ,  A61K36/28 ,  A61K36/29 ,  A61K36/31 ,  A61K36/35 ,  A61K36/48 ,  A61K36/66 ,  A61K36/68 ,  A61K36/71 ,  A61K36/76 ,  A61K36/77 ,  A61K36/808 ,  A61K36/899 ,  A61K2300/00

摘要： Disclosed herein are herbal formulations for relief from symptoms of skin disease. The formulations can also be combined with an active or inactive pharmaceutical ingredient, and/or a pharmaceutically acceptable excipient.

公开(公告)号：EP2676668A1

公开(公告)日：2013-12-25

申请号：EP12173196.2

申请日：2012-06-22

申请人： Biologische Heilmittel Heel GmbH

发明人： Burmeister, Yvonne. ,  Seilheimer, Bernd.

IPC分类号： A61K36/185 ,  A61K36/50 ,  A61K36/80 ,  A61K36/515 ,  A61K36/11 ,  A61K36/31 ,  A61K36/15 ,  A61K36/56 ,  A61K36/30 ,  A61K36/52 ,  A61K36/90 ,  A61K36/808 ,  A61P7/10

CPC分类号： A61K36/53 ,  A61K31/198 ,  A61K33/00 ,  A61K33/06 ,  A61K33/26 ,  A61K36/11 ,  A61K36/15 ,  A61K36/185 ,  A61K36/31 ,  A61K36/50 ,  A61K36/515 ,  A61K36/80 ,  A61K36/808 ,  A61K36/90 ,  A61K41/0004 ,  A61K2300/00

摘要： The present invention is concerned with plant and animal derived pharmaceutically useful compositions. In particular, it relates to for use in treating and/or preventing lymphedema, wherein said composition comprises: i) Aranea diadematus D6 dilution; ii) Calcium phosphoricum D12 dilution; iii) Equisetum hiemale D4 ex herba re dilution; iv) Ferrum jodatum D12 dilution; v) Fumaria officinalis D4 dilution; vi) Gentiana lutea D5 dilution; vii) Geranium robertianum D4 dilution; viii) Levothyroxinum D12 dilution; ix) Myosotis arvensis D3 dilution;x) Nasturtium officinale D4 dilution; xi) Natrium sulfuricum D4 dilution; xii) Pinus silvestris D4 dilution; xiii) Sarsaparillae radix D6 dilution; xiv) Scrophularia nodosa D3 dilution; xv) Teucrium scorodonia D3 dilution; and xvi) Veronica officinalis D3 dilution, and wherein said composition to be administered provides the composition in an amount corresponding to the amount provided by at least about 0.125 to 0.25 ml per kg body weight of the subject to be treated every other day. Contemplated is also a medicament comprising said composition as well as a method for treating and/or preventing lymphedema in a subject suffering therefrom, said method comprises administering in a therapeutically effective amount to the said subject a composition.

摘要翻译： 本发明涉及植物和动物衍生的药学上有用的组合物。 特别涉及用于治疗和/或预防淋巴水肿，其中所述组合物包括：i）Aranea diadematus D6稀释; ii）磷酸钙D12稀释; iii）将雌蕊的雌蕊D4稀释; iv）铁粉D12稀释; v）Fumaria officinalis D4稀释; vi）龙胆D5稀释; vii）天竺葵D4稀释; viii）左旋甲状腺D12稀释; ix）青蒿素D3稀释; x）金丝桃D4稀释; xi）硫酸铵D4稀释; xii）茜素D4稀释; xiii）Sarsaparillae radix D6稀释; xiv）耻骨球菌D3稀释; xv）Teucrium scorodonia D3稀释; 并且其中待施用的所述组合物提供的组合物的量相应于每隔一天待治疗的受试者至少约0.125至0.25ml / kg体重的量所提供的量。 考虑的是包含所述组合物的药物以及用于治疗和/或预防患有其的受试者的淋巴水肿的方法，所述方法包括以治疗有效量向所述受试者施用组合物。

公开(公告)号：EP1476174A4

公开(公告)日：2005-07-20

申请号：EP02766499

申请日：2002-10-04

申请人： WU TZU-SHENG

发明人： WU TZU-SHENG

IPC分类号： A61K31/7068 ,  A61K35/37 ,  A61K36/232 ,  A61K36/258 ,  A61K36/481 ,  A61K36/538 ,  A61K36/539 ,  A61K36/59 ,  A61K36/70 ,  A61K36/704 ,  A61K36/734 ,  A61K36/748 ,  A61K36/79 ,  A61K36/808 ,  A61K36/815 ,  A61K36/9066 ,  A61K35/78 ,  A61K38/00 ,  A61K38/24 ,  C07K1/00

CPC分类号： A61K36/79 ,  A61K31/7068 ,  A61K35/413 ,  A61K36/232 ,  A61K36/258 ,  A61K36/481 ,  A61K36/538 ,  A61K36/539 ,  A61K36/59 ,  A61K36/70 ,  A61K36/704 ,  A61K36/734 ,  A61K36/748 ,  A61K36/808 ,  A61K36/815 ,  A61K36/9066 ,  A61K2300/00

摘要： The present invention provides a method for treating patients with liver diseases by co-administrating a pharmaceutical composition and lamivudine to the patients. The pharmaceutical composition is a herbal mixture which contains, as the core ingredients, the aqueous extracts of the entire plant of Herba Hedyotidis diffusae, the rhizome of Rhizoma Bistortae, the rhizome of Rhizoma Polygoni Cuspidati, and the ripe fruit of Fructus Schisandrae. The present invention also provides methods for preventing a relapse of hepatitis in patients after the lamivudine treatment has been discontinued and for suppressing the development of lamivudine drug resistance in patients by providing the lamivudine-treated patients with the pharmaceutical composition of the present invention.

公开(公告)号：EP1328284A4

公开(公告)日：2004-07-07

申请号：EP01981783

申请日：2001-10-18

申请人： WU TZU SHENG ,  WU BERTOLOTTI JY YUAN

发明人： WU TZU-SHENG

IPC分类号： A61K9/16 ,  A61K20060101 ,  A61K9/48 ,  A61K35/12 ,  A61K35/37 ,  A61K35/38 ,  A61K35/407 ,  A61K35/413 ,  A61K36/00 ,  A61K36/18 ,  A61K36/232 ,  A61K36/25 ,  A61K36/258 ,  A61K36/481 ,  A61K36/53 ,  A61K36/539 ,  A61K36/59 ,  A61K36/70 ,  A61K36/704 ,  A61K36/73 ,  A61K36/734 ,  A61K36/748 ,  A61K36/75 ,  A61K36/79 ,  A61K36/808 ,  A61K36/815 ,  A61K36/9066 ,  A61P1/16 ,  A61P25/32 ,  A61P31/14 ,  A61P31/18 ,  A61P31/20 ,  A61P35/00 ,  A61P43/00 ,  A61K35/78

CPC分类号： A61K36/00 ,  A61K36/232 ,  A61K36/258 ,  A61K36/481 ,  A61K36/539 ,  A61K36/59 ,  A61K36/70 ,  A61K36/704 ,  A61K36/734 ,  A61K36/748 ,  A61K36/79 ,  A61K36/808 ,  A61K36/815 ,  A61K36/9066 ,  Y10S514/893 ,  Y10S514/894 ,  A61K2300/00

摘要： The present invention provides a herbal pharmaceutical composition for treating patients with liver diseases and/or HIV. The composition contains fifteen (15) ingredients, which are diffuse hedyotis, bistort rhizome, giant knotweed rhizome, Asiatic moonseed rhizome, baical skullcap root, bovine biliary powder, milkvetch root, barbary wolfberry fruit, sanqi, red ginseng, figwort root, Chinese magnoliavine fruit, turmeric root-tuber, hawthorn fruit, and Chinese angelica. Among the fifteen (15) ingredients, diffuse hedyotis, bistort rhizome, giant knotweed rhizome, and Chinese magnoliavine fruit are the required herbs which contribute to the efficacy of the pharmaceutical composition.

公开(公告)号：EP1386614A1

公开(公告)日：2004-02-04

申请号：EP03009015.3

申请日：2003-04-17

申请人： Wu, Tzu-Sheng

发明人： Wu, Tzu-Sheng

IPC分类号： A61K35/78 ,  A61K35/413

CPC分类号： A61K36/185 ,  A61K36/232 ,  A61K36/258 ,  A61K36/481 ,  A61K36/535 ,  A61K36/539 ,  A61K36/59 ,  A61K36/70 ,  A61K36/704 ,  A61K36/734 ,  A61K36/748 ,  A61K36/79 ,  A61K36/808 ,  A61K36/815 ,  A61K36/9066 ,  A61K2300/00

摘要： The present invention provides a pharmaceutical composition for treating patients with HIV infection. The pharmaceutical composition is in the form of an intravenous injection solution and optionally capsules. The pharmaceutical composition contains fourteen (14) ingredients, i.e. , diffuse hedyotis, bistort rhizome, giant knotweed rhizome, Asiatic moonseed rhizome, baical skullcap root, bovine biliary powder, milkvetch root, barbary wolfberry fruit, sanqi, figwort root, Chinese magnoliavine fruit, turmeric root-tuber, hawthorn fruit, and Chinese angelica.

摘要翻译： 本发明提供了用于治疗HIV感染患者的药物组合物。 药物组合物是静脉内注射溶液和任选的胶囊形式。 药物组合物含有十四（14）种成分，分别是扩散性水蛭，双岐根茎，巨型eed根，亚洲响应根茎，黄芩，牛胆，牛蒡根，枸杞子，三旗，玄参，中国枸杞子， 姜黄根瘤，山楂果和当归。

公开(公告)号：EP3403663A1

公开(公告)日：2018-11-21

申请号：EP17201472.2

申请日：2012-05-15

申请人： Haus Bioceuticals, Inc.

发明人： YESUDAS, Tomy ,  ALEX, Philip ,  CENTOLA, Michael ,  PAYNE, Adam, Joshua

IPC分类号： A61K36/185 ,  A61K36/48 ,  A61K36/23 ,  A61K36/899 ,  A61K36/77 ,  A61K36/29 ,  A61K36/28 ,  A61K36/76 ,  A61K36/35 ,  A61K36/22 ,  A61K36/27 ,  A61K36/31 ,  A61K36/71 ,  A61K36/808 ,  A61K36/90 ,  A61K36/66 ,  A61K36/68

CPC分类号： A61K36/90 ,  A61K36/185 ,  A61K36/22 ,  A61K36/23 ,  A61K36/24 ,  A61K36/27 ,  A61K36/28 ,  A61K36/29 ,  A61K36/31 ,  A61K36/35 ,  A61K36/48 ,  A61K36/66 ,  A61K36/68 ,  A61K36/71 ,  A61K36/76 ,  A61K36/77 ,  A61K36/808 ,  A61K36/899 ,  A61K2300/00

摘要： Disclosed herein are herbal formulations developed for the management of acute and chronic inflammatory conditions and infectious diseases. The formulations can also be combined with an active or inactive pharmaceutical ingredient, and/or a pharmaceutically acceptable excipient.