摘要:
Apparatus for producing liquid droplets (for example an aerosol) is described. The apparatus comprises a vibratory element (106) arranged, in use of the apparatus, to vibrate an aperture plate (102) having at least one aperture therein. Also provided is a sealing element (202), which is arranged to provide a liquid tight seal over at least a portion of the vibratory element (106). The sealing element (202) comprises a closed cell foam material. In some embodiments, sealing element (202) may be molded over other elements of the apparatus, including the vibratory element (106).
摘要:
Inhalationstherapievorrichtung mit einer Atemluftstromerzeugungseinrichtung (3) für die Erzeugung einer Atemluftströmung (4) und Förderung der Atemluftströmung (4) in eine Zuführleitung (32); einer Vernebelungskammer (5) mit einer Atemluftzuführöffnung (51) an der die Zuführleitung (32) angeschlossen ist und einem Bereich (52), der eine Austrittsöffnung (53) mit einem Stutzen (54) bildet, um das Flüssigkeitströpfchen/Atemluft-Gemisch aus der Verneblungskammer auszugeben, und einer Aerosolerzeugungseinrichtung (1) mit einer Membran (13) und einem die Membran in Schwingungen versetzenden Piezo-Schwinger für die Vernebelung eines Fluids und Bereitstellung von Flüssigkeitströpfchen; dadurch gekennzeichnet, dass die Inhalationstherapievorrichtung ausgestaltet ist, die Aerosolerzeugungseinrichtung (1) über ein Ansteuersignal an den Piezo-Schwinger wechselnd ein- bzw. auszuschalten, wobei die Inhalationstherapievorrichtung ausgestaltet ist, EIN/AUS-Schaltphasen der Aerosolerzeugungseinrichtung (1) zu Ändern und dadurch eine Outputrate der Aerosolerzeugungseinrichtung anzupassen bzw. einzustellen.
摘要:
Devices and methods to heat and cool human beings, including inducing and maintaining hypothermia in human patients. Methods include inducing hypothermia to treat ischemic events, including heart attack and stroke, to limit damage caused by the ischemic event. Methods can include: using the lungs for heat exchange; using cooled gases for ventilation; using helium in the ventilation gas mixture, using medications to control reflex heat production; and injecting a perfluorocarbon mist into the gas stream to increase the cooling rate. The high thermal conductivity and diffusivity of helium results in greater inspired gas temperature equalization toward body temperature. Due to the latent heat of vaporization, addition of even small quantity of phase-change perfluorocarbon dramatically increases the heat carrying capacity of the respiratory gases. Hypothermia may be terminated by discontinuing the medications and warming the patient using a warmed helium-oxygen mixture.
摘要:
In respiratory care with liquids, the patient (2) is connected to a liquid apparatus (6) and a ventilator (10) for supplying and removing a treatment liquid and a breathing gas respectively to/from the patient (2). The exchange of gases between the breathing gas and the treatment liquid is improved with a device according to the invention. In one embodiment, the device consists of a breathing gas generator (12) which generates different frequencies to cause the breathing gas and treatment liquid to oscillate at appropriate frequencies. In an alternative embodiment, the device consists of a vibrator unit (22) which is applied to the chest to cause the treatment liquid to oscillate. In a third embodiment, the device consists of a magnetic field generator (26) for generating a magnetic field across the lungs and setting electrically conductive components in the treatment liquid in motion.
摘要:
In accordance with the present invention there are provided devices and methods for facilitating the transfer of gas between liquid and gas phases. Invention devices and methods employ fluid dispersion units that cast liquid in the form of discrete thin planar layers. In this manner, the liquid assumes a dispersion of droplets which, owing to their size-to-volume ratio, allow for efficient mass transfer between the gas and liquid phases. Invention devices and methods find particular application in the field of liquid ventilation, wherein a patient is exhausting carbon dioxide and obtaining oxygen through a partially or completely liquid medium such as a perfluorocarbon.
摘要:
A process is provided for controlling a ventilation procedure wherein a liquid ventilation system passes breathing liquid through at least a portion of a patient's pulmonary pathways. In this process, desired ranges for certain process parameters associated with the liquid ventilation system are established. These desired ranges are input into a central processing unit (50). Initial settings for the liquid ventilation system are then made such that the actual conditions which will initially occur during the liquid ventilation procedure fall within their respective desired ranges. Thereafter, the procedure is commenced. During the procedure, conditions are continually monitored by sensors (16, 21, 27). The CPU (50) compares the sensor readings with the desired ranges, and acts to correct any discrepancy. The CPU can trigger alarms (514).
摘要:
Method and means for maintaining respiratory gas exchange by introducing into the pulmonary air passages (18) of a mammalian host a volume of perfluorocarbon liquid substantially equivalent to the pulmonary functional residual capacity of the host, maintaining respiratory gas exchange in the perfluorocarbon liquid-laden pulmonary air passages (18) by continuous positive pressure breathing or otherwise with a conventional gas respirator (12), for up to an hour or more, and thereafter evaporating the perfluorocarbon liquid from the pulmonary air passages. Useful for treating pulmonary surfactant deficiency or dysfunction.