公开(公告)号：EP0795336B1

公开(公告)日：2003-06-11

申请号：EP96930407.0

申请日：1996-09-13

申请人： TAKIRON CO. LTD.

发明人： SHIKINAMI, Yasuo, Takiron Co., Ltd. ,  OKUNO, Masaki, Takiron Co., Ltd.

IPC分类号： A61L27/00 ,  B29C43/02 ,  B29C43/16

CPC分类号： C08L67/04 ,  A61L27/46 ,  A61L27/58 ,  A61L31/06 ,  A61L31/127 ,  A61L31/14 ,  A61L31/148 ,  A61L31/18 ,  B29C43/02 ,  B29C43/16 ,  B29C2791/001 ,  B29K2067/043 ,  B29K2067/046 ,  B29K2105/0005 ,  B29K2105/16 ,  B29K2105/251 ,  B29K2105/255 ,  B29K2267/043 ,  B29K2995/0041 ,  B29K2995/0051 ,  B29K2995/0059 ,  B29K2995/006 ,  B29L2031/7532 ,  A61L27/18 ,  A61F2/28 ,  A61B17/58

公开(公告)号：EP0795336A4

公开(公告)日：2000-12-20

申请号：EP96930407

申请日：1996-09-13

申请人： TAKIRON CO

发明人： SHIKINAMI YASUO ,  OKUNO MASAKI

IPC分类号： A61B17/58 ,  A61F2/28 ,  A61L27/00 ,  A61L27/46 ,  A61L27/58 ,  A61L31/06 ,  A61L31/12 ,  A61L31/14 ,  A61L31/18 ,  B29C43/02 ,  B29C43/16 ,  C08L67/04

CPC分类号： C08L67/04 ,  A61L27/46 ,  A61L27/58 ,  A61L31/06 ,  A61L31/127 ,  A61L31/14 ,  A61L31/148 ,  A61L31/18 ,  B29C43/02 ,  B29C43/16 ,  B29C2791/001 ,  B29K2067/043 ,  B29K2067/046 ,  B29K2105/0005 ,  B29K2105/16 ,  B29K2105/251 ,  B29K2105/255 ,  B29K2267/043 ,  B29K2995/0041 ,  B29K2995/0051 ,  B29K2995/0059 ,  B29K2995/006 ,  B29L2031/7532 ,  A61L27/18 ,  A61F2/28 ,  A61B17/58

摘要： A high-bending-strength and high-density osteosynthetic material and a high-strength implant material, comprising either a biodegradable and bioabsorbable crystalline thermoplastic polymer material or a composite material comprising the above polymer material and a bioceramic powder having a particle diameter of 0.2 to 50 νm dispersed therein, wherein crystals of the polymer material are pressure-oriented essentially parallel to a plurality of reference axes rather than uniaxially; and a process for preparing the above materials by pressure orientation, comprising preparing either a biodegradable and bioabsorbable crystalline thermoplastic polymer material or a mixture comprising a dispersion of a biodegradable and bioabsorbable crystalline thermoplastic polymer material and a dispersion of a bioceramic powder, melt-forming the mxiture into a preform, and pressure filling the preform into a cavity of a closed mold to prepare an oriented form. This process enables the preparation of ideal biomaterials, i.e., an osteosynthetic material and an implant material comprising an oriented form with crystals oriented parallel to a plurality of reference axes and possessing low anisotropy, high denseness, and high strength, which have suitable hydrolyzability, can retain satisfactory strength for a period of time necessary for bone coaptation and, after the recovery of the fractured portion, is degraded and adsorbed at such a rate as will not cuase any inflammation, thus eliminating the need to conduct reoperation.

公开(公告)号：EP1948264B1

公开(公告)日：2012-05-23

申请号：EP06800681

申请日：2006-08-01

申请人： ABBOTT CARDIOVASCULAR SYSTEMS

发明人： HUANG BIN ,  GALE DAVID C ,  SRIDHARAN SRINIVASAN ,  KLEINE KLAUS ,  HOSSAINY SYED F A ,  LEE JEONG ,  LIMON TIMOTHY ,  ABBATE ANTHONY J ,  CALLOL JOE

IPC分类号： A61L31/12 ,  A61F2/90

CPC分类号： A61F2/915 ,  A61F2/04 ,  A61F2/06 ,  A61F2/90 ,  A61F2/91 ,  A61F2002/072 ,  A61F2002/91508 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2210/0009 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2230/0013 ,  A61F2250/0098 ,  A61L31/129 ,  B23K26/402 ,  B23K26/50 ,  B23K2203/42 ,  B23K2203/50 ,  B29C43/02 ,  B29C45/0001 ,  B29C45/0005 ,  B29C45/0055 ,  B29C47/0004 ,  B29C47/0023 ,  B29C47/0026 ,  B29C47/0066 ,  B29C47/06 ,  B29C47/1045 ,  B29C53/566 ,  B29C53/583 ,  B29C59/02 ,  B29C59/021 ,  B29C2043/028 ,  B29K2101/00 ,  B29K2105/12 ,  B29K2267/043 ,  B29K2995/0056 ,  B29K2995/006 ,  B29L2023/003 ,  B29L2031/7546 ,  D03D3/02

摘要： Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.

摘要翻译： 公开了用纤维增强的用于植入体腔的聚合复合支架。

公开(公告)号：EP1948264A2

公开(公告)日：2008-07-30

申请号：EP06800681.6

申请日：2006-08-01

申请人： Abbott Cardiovascular Systems Inc.

发明人： HUANG, Bin ,  GALE, David C. ,  SRIDHARAN, Srinivasan ,  KLEINE, Klaus ,  HOSSAINY, Syed F.a. ,  LEE, Jeong ,  LIMON, Timothy ,  ABBATE, Anthony J. ,  CALLOL, Joe

IPC分类号： A61L31/12

CPC分类号： A61F2/915 ,  A61F2/04 ,  A61F2/06 ,  A61F2/90 ,  A61F2/91 ,  A61F2002/072 ,  A61F2002/91508 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2210/0009 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2230/0013 ,  A61F2250/0098 ,  A61L31/129 ,  B23K26/402 ,  B23K26/50 ,  B23K2203/42 ,  B23K2203/50 ,  B29C43/02 ,  B29C45/0001 ,  B29C45/0005 ,  B29C45/0055 ,  B29C47/0004 ,  B29C47/0023 ,  B29C47/0026 ,  B29C47/0066 ,  B29C47/06 ,  B29C47/1045 ,  B29C53/566 ,  B29C53/583 ,  B29C59/02 ,  B29C59/021 ,  B29C2043/028 ,  B29K2101/00 ,  B29K2105/12 ,  B29K2267/043 ,  B29K2995/0056 ,  B29K2995/006 ,  B29L2023/003 ,  B29L2031/7546 ,  D03D3/02

摘要： Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.

公开(公告)号：EP0795336A1

公开(公告)日：1997-09-17

申请号：EP96930407.0

申请日：1996-09-13

申请人： TAKIRON CO. LTD.

发明人： SHIKINAMI, Yasuo, Takiron Co., Ltd. ,  OKUNO, Masaki, Takiron Co., Ltd.

IPC分类号： A61L27/00 ,  B29C43/02 ,  B29C43/16

CPC分类号： C08L67/04 ,  A61L27/46 ,  A61L27/58 ,  A61L31/06 ,  A61L31/127 ,  A61L31/14 ,  A61L31/148 ,  A61L31/18 ,  B29C43/02 ,  B29C43/16 ,  B29C2791/001 ,  B29K2067/043 ,  B29K2067/046 ,  B29K2105/0005 ,  B29K2105/16 ,  B29K2105/251 ,  B29K2105/255 ,  B29K2267/043 ,  B29K2995/0041 ,  B29K2995/0051 ,  B29K2995/0059 ,  B29K2995/006 ,  B29L2031/7532 ,  A61L27/18 ,  A61F2/28 ,  A61B17/58

摘要： A high bending strength and high density material for osteosynthesis, which comprises a biodegradable and bioabsorbable crystalline thermoplastic polymer material, and a high strength implant material, comprising a composite material in which a bioceramics powder of from 0.2 to 50 µm in particle size is dispersed in the polymer material, wherein crystals of the polymer material are pressure-oriented not in a uni-axial direction but basically in parallel with a plurality of reference axes; and a production method by pressure orientation, which comprises preparing in advance a biodegradable and bioabsorbable crystalline thermoplastic polymer material or a dispersed mixture of the polymer material and a bioceramics powder and melt-molding it into a pre-molded material which is then press-charged at a cold temperature into a cavity of a closed type forming mold, thereby obtaining an oriented molding. Since the osteosynthesis and implant materials are dense and high strength oriented moldings having less anisotropy in which crystals are oriented in parallel with a plurality of reference axes, excellent ideal biomaterials can be provided which have appropriate hydrolysis property, can maintain sufficient strength during a period required for bone union and are degraded and absorbed at such a rate that they do not induce inflammatory reactions after healing of the fractured bones so that re-operation is not required.

摘要翻译： 高弯曲强度和高密度的骨接合术材料，它包括一种可生物降解和生物吸收的结晶热塑聚合物材料，并且具有高强度的植入材料，其包含一种复合材料，其中的从0.2到50微米的颗粒尺寸的生物陶瓷粉末分散 在聚合物材料中，所述聚合物材料的worin晶体是压力导向不是在单一轴方向上，但基本上与参考轴的多个平行; 并通过压力取向，该方法包括在预先制备一种可生物降解和生物吸收的结晶热塑聚合物材料或聚合物材料的分散的混合物和生物陶瓷粉末及其制造方法熔融模塑成一个前模塑材料的所有其然后按充电 在低温下成密闭型成形模具的空腔，从而得到取向的模塑件的。 由于骨接合术和植入物材料是具有较少各向异性致密且高强度的取向模塑件中哪结晶取向平行的基准轴复数，能够提供具有适当的水解性，可在所需的期间保持足够的强度优异的理想的生物材料 对于骨性愈合，并降低和速度搜索thatthey所以根本不需要再次手术的骨头骨折愈合后不引起炎症反应吸收。