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    ONIUM SALTS AND THE USE THEROF AS LATENT ACIDS
    3.
    发明授权
    ONIUM SALTS AND THE USE THEROF AS LATENT ACIDS 有权
    鎓盐及其用途为递延ACIDS

    公开(公告)号：EP1344109B1

    公开(公告)日：2008-05-07

    申请号：EP01989514.3

    申请日：2001-11-26

    申请人： Ciba Holding Inc.

    发明人： YAMATO, Hitoshi ,  ASAKURA, Toshikage ,  MATSUMOTO, Akira ,  OHWA, Masaki

    IPC分类号： G03F7/004

    CPC分类号： C07H9/04 ,  B33Y70/00 ,  C07B2200/11 ,  C07C25/18 ,  C07C305/06 ,  C07C305/20 ,  C07C305/22 ,  C07C305/24 ,  C07C381/12 ,  C07C2601/14 ,  C07D309/06 ,  C07D317/54 ,  C07D333/16 ,  C08G59/68 ,  C08G65/105 ,  C40B40/00 ,  G03F7/0045 ,  G03F7/039 ,  Y10S430/111 ,  Y10S430/115 ,  Y10S430/118 ,  Y10S430/122 ,  Y10S430/123

    摘要： A chemically amplified photoresist composition comprising, (a) a compound which cures upon the action of an acid or a compound whose solubility is increased upon the action of an acid; and (b) as photosensitive acid donor, at least one compound of the formula Ia, Ib, Ic, IIb or IIc wherein R1 is for example C1-C5alkyl, C3-C30cycloalkyl, C1-C5haloalkyl, C2-C12alkenyl, C4-C8cycloalkenyl, C6-C12bicycloalkenyl, phenyl, naphthyl, anthracyl, phenanthryl, or is a heteroaryl radical; all of which are unsubstituted or substituted; optionally some of the substituents form 5- or 6-membered rings with further substituents on the phenyl, naphthyl, anthracyl, phenanthryl, or heteroaryl ring or with one of the carbon atoms of the phenyl, naphtyl, anthracyl, phenanthryl, or heteroaryl ring; R'1 is for example C1-C12alkylene , C3-C30cycloalkylene, phenylene, naphtylene, diphenylene, or oxydiphenylene, wherein these radicals are unsubstituted or substituted; A and B for example are a direct bond; Ar1 and Ar2 independently of each other for example are phenyl, naphtyl, anthracyl, phenanthryl, or heteroaryl, all of which are unsubstituted or are substituted; Ar3, Ar4 and Ar5 for example have one of the meanings given for Ar1 and Ar2; Y is for example C3-C3-C30cycloalkylene, phenylene, naphthylene, diphenylene, or oxydiphenylene, all of which are unsubstituted or substituted.

    BENZAMIDIN-DERIVATE MIT EINER SULFAT-GRUPPE ALS LTB4-ANTAGONISTEN
    5.
    发明公开
    BENZAMIDIN-DERIVATE MIT EINER SULFAT-GRUPPE ALS LTB4-ANTAGONISTEN 审中-公开
    与氯基AS LTB4拮抗剂苯甲脒衍生物

    公开(公告)号：EP1332128A1

    公开(公告)日：2003-08-06

    申请号：EP01978439.6

    申请日：2001-10-19

    申请人： Boehringer Ingelheim Pharma KG

    发明人： ANDERSKEWITZ, Ralf ,  SCHROMM, Kurt ,  BIRKE, Franz ,  JENNEWEIN, Hans, Michael

    IPC分类号： C07C305/24 ,  A61K31/095

    CPC分类号： C07C305/24

    摘要： The invention relates to novel sulfoxybenzamides of formula (I), wherein: Z0 represents a group selected among formulas -X1-(CH2)r-X2- and -CR?4R5-; A1 and A2¿, independent of one another, represent a 1,4-phenylene group or 1,3-phenylene group optionally substituted by one or more halogen atoms, C¿1?-C8 alkyl groups, C2-C8 alkenyl groups, C1-C8 alkyl halide groups or by C1-C8 alkoxy groups; Z?1 and Z2¿, independent of one another, represent a group of formula -X3-(CH2)8-X4- or a single bond; m and n, independent of one another, represent 0 or 1, and; radicals R?1, R2, R3, R4, R5, X1, X2, X3, X4¿, r and s have the meanings cited in the description. The invention also relates to a method for producing these novel compounds and to their use as medicaments, especially as leukotriene B¿4?(LTB4) antagonists.

    SUBSTITUTED CHALCONES AS THERAPEUTIC COMPOUNDS
    6.
    发明公开
    SUBSTITUTED CHALCONES AS THERAPEUTIC COMPOUNDS 有权
    取代查耳酮为药物

    公开(公告)号：EP1284952A1

    公开(公告)日：2003-02-26

    申请号：EP01914064.9

    申请日：2001-03-26

    申请人： Cancer Research Technology Limited

    发明人： POTTER, Gerard, Andrew ,  BUTLER, Paul, Crispin ,  WANOGHO, Elugba

    IPC分类号： C07C49/84 ,  A61P29/00 ,  A61P35/00 ,  A61K31/12

    CPC分类号： G01N33/574 ,  A61K31/12 ,  A61K31/15 ,  A61K31/222 ,  C07C69/017 ,  C07C251/40 ,  C07C305/24 ,  C07F9/12 ,  G01N2333/90209

    摘要： This invention pertains to substituted chalcones, specifically substituted 1-(4-methoxyphenyl)-3-(3,5-dimethoxyphenyl)prop-1-en-3-ones, which have therapeutic application, for example, as potent antiproliferative agents and antiinflammatory agents, and which have the formula (I) wherein: X is -H, -OH, -OC(=O)R3, -OS(=O)¿2?OH, or -OP(=O)2(OH)2; Y is -H or a C1-4alkyl group; Z is -H or -OCH3; R?1¿ is -H, a C¿1?-4alkyl group, or C1-4fluoroalkyl group; R?2¿ is -H, a C¿1?-4alkyl group, or C1-4fluoroalkyl group; and, R3 is -H, a C1-6alkyl group, a C3-20 heterocyclyl group, or a C5-20aryl group; and pharmaceutically acceptable salts, esters, and protected forms thereof. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, for both diagnosis and treatment of, for example, proliferative conditions, such as cancer, and inflammatory conditions.