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1.发明公开Methods of synthesizing pharmaceutical salts of a factor XA inhibitor 有权Verfahren zur Synthetisierung pharmazeutischer Salze aus einem Faktor XA-Hemmer
公开(公告)号：EP2404906A1
公开(公告)日：2012-01-11
申请号：EP11183853.8
申请日：2007-11-01
IPC分类号： C07D213/75 , A61K31/44 , A61P7/00
CPC分类号： C07D213/90 , C07D213/75
摘要： Novel methods of preparing a compound of Formula I which is an inhibitor of Factor Xa and its maleate salt, are described herein.
摘要翻译： 本文描述了制备作为因子Xa及其马来酸盐的抑制剂的式I化合物的新方法。
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公开(公告)号：EP2077995A1
公开(公告)日：2009-07-15
申请号：EP07863800.4
申请日：2007-11-01
IPC分类号： C07D213/75 , A61K31/44 , A61P7/00
CPC分类号： C07D213/90 , C07D213/75
摘要： Novel methods of preparing a compound of Formula I which is an inhibitor of Factor Xa and its maleate salt, are described herein.
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公开(公告)号：EP1309558A1
公开(公告)日：2003-05-14
申请号：EP01974985.2
申请日：2001-08-15
发明人： LEMMENS, Jacobus, Maria , PETERS, Theodorus, Hendricus, Antonius , BENNEKER, Franciscus, Bernardus, Gemma
IPC分类号： C07D211/90 , A61K31/4418 , A61P9/12
CPC分类号： C07D213/90
摘要： An amlodipine derivative having the following formula is useful, either alone or in combination with amlodipine, as a pharmaceutical in treating angina and hypertension.
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4.发明授权
公开(公告)号：EP0993445B1
公开(公告)日：2002-08-28
申请号：EP98937513.4
申请日：1998-06-19
发明人： YAMATO, Hitoshi , BLEIER, Hartmut , BIRBAUM, Jean-Luc , KUNZ, Martin , DIETLIKER, Kurt , DE LEO, Christoph , ASAKURA, Toshikage
IPC分类号： C07C381/00 , C07C309/65 , C07C309/66 , C07C309/73 , C07C323/63 , C07D207/44 , C07D213/90 , C07D333/34 , C07D333/44 , G03F7/004
CPC分类号： C07D207/44 , B33Y70/00 , C07C309/65 , C07C309/66 , C07C309/73 , C07C323/63 , C07C381/00 , C07D213/90 , C07D333/44 , G03F7/0045 , Y10S430/114 , Y10S430/117 , Y10S430/12 , Y10S430/122
摘要： New oximsulfonate compounds of formulae (I) or (II), wherein m is 0 or 1; x is 1 or 2; R1 is, for example phenyl, which is unsubstituted or substituted or R1 is a heteroaryl radical that is unsubstituted or substituted, or, if m is 0, R1 additionally is C2-C6alkoxycarbonyl, phenoxycarbonyl or CN; R'1 is for example C2-C12alkylene, phenylene; R2 has for example one of the meanings of R1; n is 1 or 2; R3 is for example C1-C18alkyl, R'3 when x is 1, has one of the meanings given for R3, or R'3 in formula (IV) and when x is 2 in formula (I), is for example C2-C12 alkylene, phenylene; R4 and R5 are independently of each other for example hydrogen, halogen, C1-C6alkyl; R6 is for example hydrogen, phenyl; R7 and R8 are independently of each other for example hydrogen or C1-C12alkyl; R9 is for example C1-C12alkyl; A is S, O, NR6, or a group of formula (A1), (A2), (A3) or (A4); R10 and R11 independently of each other have one of the meanings given for R4; R12, R13, R14 and R15 independently of one another are for example hydrogen, C1-C4alkyl; Z is CR11 or N; Z1 is -CH2-, S, O or NR6, are useful as latent sulfonic acids, especially in photoresist applications.
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5.发明公开Pyridine-2,3,6-triones, process for their manufacture, their use as silver dye-bleach catalysts and photographic process 失效吡啶-2,3,6-三酮，它们的制备方法，它们作为催化剂的银染料漂白方法和摄影过程中使用。
公开(公告)号：EP0018317A1
公开(公告)日：1980-10-29
申请号：EP80810092.9
申请日：1980-03-20
申请人： CIBA-GEIGY AG
发明人： Long, William Edward
IPC分类号： C07D213/85 , C07D213/82 , G03C5/52
CPC分类号： C07D213/90
摘要： New silver dye-bleach catalysts and the process for their manufacture are provided. These compounds have the general formula
wherein A is an electron-withdrawing group and R 1 and R 2 are hydrogen, optionally substituted alkyl or optionally substituted aryl.-
公开(公告)号：EP3362436A1
公开(公告)日：2018-08-22
申请号：EP16775090.0
申请日：2016-09-14
IPC分类号： C07D213/80 , C07C67/20 , C07D213/81 , C07D213/90
CPC分类号： C07D213/90 , C07C67/20 , C07D213/80 , C07D213/81 , C07C69/78
摘要： The present invention relates to a catalytic method for the conversion of amide-containing compouds by means of a build-in directing group and upon the action of a heteronucleophilic compound (in se an amine (RNH2 or RNHR') or an alcohol (ROH) or a thiol (RSH)) in the presence of a metal catalyst to respectively esters, thioesters, carbonates, thiocarbonates and to what is defined as amide-containing compounds (such as carboxamides, urea, carbamates, thiocarbamates). The present invention also relates to these amide-containing compounds having a build-in directing group (DG), as well as the use of such directing groups in the catalytic directed cleavage of N-DG amides with the use of heteronucleophiles (in se an amine (RNH2 or RNHR') or an alcohol (ROH) or thiol (RSH)).
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公开(公告)号：EP0887385B1
公开(公告)日：2002-03-06
申请号：EP98201992.9
申请日：1998-06-15
发明人： Chapman, Derek David, Eastman Kodak Company , Goswami, Ramanuj, Eastman Kodak Company , Kovacs, Csaba Andras, Eastman Kodak Company
IPC分类号： C09B45/00
CPC分类号： C09B45/00 , C07D213/90 , G11B7/2467 , G11B7/249 , G11B7/2492 , G11B7/2534 , G11B7/256 , G11B7/2575 , G11B7/2595 , G11B2007/24612
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公开(公告)号：EP0767220B1
公开(公告)日：1999-04-28
申请号：EP96114578.6
申请日：1996-09-12
申请人： BAYER AG
IPC分类号： C09B29/36 , C07C255/23 , C07D213/64 , C07D213/80 , C07D213/85 , C07D213/75 , C07D221/16 , C07D417/06 , C09B31/153
CPC分类号： C07D221/04 , C07C255/30 , C07D213/90 , C07D409/04 , C07D417/06 , C07D417/12 , C07D471/04 , C09B29/3621 , C09B31/153 , C09B44/00 , C09B62/006
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公开(公告)号：EP0552010B1
公开(公告)日：1997-09-17
申请号：EP93300168.7
申请日：1993-01-12
发明人： Hall, Kevin, P. , Mott, Andrew, W.
CPC分类号： G03C1/832 , C07D213/90 , C07D231/22 , C09B23/0075 , C09B23/0091
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10.发明授权
公开(公告)号：EP2404906B1
公开(公告)日：2015-07-15
申请号：EP11183853.8
申请日：2007-11-01
IPC分类号： C07D213/75 , A61K31/44 , A61P7/00
CPC分类号： C07D213/90 , C07D213/75
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