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    BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES
    3.
    发明公开
    BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES 有权
    可生物吸收和生物相容性的聚氨酯和医疗器械的聚酰胺

    公开(公告)号：EP1937182A4

    公开(公告)日：2009-07-15

    申请号：EP06814181

    申请日：2006-09-06

    申请人： BEZWADA BIOMEDICAL LLC

    发明人： BEZWADA RAO S

    IPC分类号： A61F2/00 ,  C08G18/52

    CPC分类号： A61L27/18 ,  A61K47/34 ,  A61L17/105 ,  A61L24/043 ,  A61L24/046 ,  A61L31/10 ,  C08G18/10 ,  C08G18/711 ,  C08G18/771 ,  C08G69/26 ,  C08G69/44 ,  C08G2230/00 ,  C09J175/06 ,  C08L67/04 ,  C08L77/00 ,  C08L75/04

    摘要： Absorbable polyurethanes, polyamides and polyester urethanes prepared from at least one compound selected from (formula)or the diamines and diisocyanates thereof, wherein each X represents a member independently selected from -CH2COO- (glycolic acid moiety), -CH(CH3)COO- (lactic acid moiety), -CH2CH2OCH2COO- (dioxanone), -CH2CH2CH2CH2CH2COO- (caprolactone moiety), -(CH2)yCOO- where y is one of the numbers 2, 3, 4 or 6- 24 inclusive, and -( CH2CH2O)Z CH2COO- where z' is an integer between 2 and 24, inclusive; each Y represents a member independently selected from -COCH2O- (glycolic ester moiety), -COCH(CH3)O- (lactic ester moiety), -COCH2OCH2CH2O- (dioxanone ester), -COCH2CH2CH2CH2CH2O- (caprolactone ester), -CO(CH2)mO- where m is an integer between 2, 3, 4 or 6 - 24 inclusive, -COCH2O(CH2CH2O)n- where n is an integer between 2 and 24, inclusive; R' is hydrogen, benzyl or an alkyl group, the alkyl group being either straight-chained or branched; p is an integer between 1 and 4, inclusive; and Rn represents one or more members selected from H, alkoxy, benzyloxy, aldehyde, halogen, carboxylic acid and -NO2, which is attached directly to an aromatic ring or attached through an aliphatic chain. Absorbable polymers prepared from these compounds are useful for drug delivery, tissue engineering, tissue adhesives, adhesion prevention and other implantable medical devices.