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公开(公告)号：EP3385371A1
公开(公告)日：2018-10-10
申请号：EP18174895.5
申请日：2013-10-11
摘要： La présente invention concerne un procédé de culture in vitro en milieu de culture acellulaire, de bactérie dont la croissance est sensible à la teneur en oxygène, la croissance optimale de la dite bactérie exigeant une atmosphère d'incubation à teneur en oxygène relativement réduite par rapport à la teneur en oxygène de l'air, ladite bactérie étant choisie parmi les bactéries anaérobies, caractérisé en ce que l'on ajoute dans le dit milieu de culture acellulaire un composé antioxydant choisi de préférence parmi l'acide ascorbique, le glutathion et l'hydrosulfure de sodium, et l'on cultive la dite bactérie dans ledit milieu de culture en présence d'oxygène.
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公开(公告)号：EP3374514A1
公开(公告)日：2018-09-19
申请号：EP16793896.8
申请日：2016-11-09
申请人： Ares Trading S.A.
发明人： BRUHLMANN, David , JORDAN, Martin
IPC分类号： C12P21/00
CPC分类号： C12N1/38 , C07K19/00 , C12N5/0037 , C12N5/0682 , C12N15/85 , C12N2015/8518 , C12N2500/34 , C12N2501/90 , C12N2510/02 , C12N2511/00 , C12P21/005
摘要： The present invention relates to methods and compositions for modulating glycosylation of recombinant proteins expressed by mammalian host cells during the cell culture process. Also disclosed are methods of culturing a host cell expressing a recombinant protein in a cell culture medium comprising a disaccharide or a trisaccharide, while keeping the osmolality constant.
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3.发明公开
公开(公告)号：EP3365457A1
公开(公告)日：2018-08-29
申请号：EP16791175.9
申请日：2016-10-19
摘要： A method for enhancing yeast growth for bioproduct production is described. A method for fermentative bioproduct production also is provided. A nutrient composition used in the methods also is described. A liquid mixture containing the nutrient composition, yeast culture (or fungi, algae, or bacteria culture), and sugars also is provided.
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公开(公告)号：EP3018198B1
公开(公告)日：2018-07-25
申请号：EP14192180.9
申请日：2014-11-07
发明人： Tanner, Reijo , Seppälä, Jukka , Tamminen, Timo , Spilling, Kristian , Ylöstalo, Pasi , Uronen, Pauliina
CPC分类号： C12N1/12 , C12N1/38 , C12P7/6463
摘要： The present description is related to the field of cultivating algae. It introduces a method of cultivating algae by depleting the culture of an inorganic nutrient and exposing the alga to high intensity light to obtain algal cell mass having enriched lipid content and reduced chlorophyll content.
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公开(公告)号：EP2493464B8
公开(公告)日：2018-06-27
申请号：EP10827568.6
申请日：2010-10-29
IPC分类号： A61K31/10 , A61K31/437 , A61K31/43 , A61K31/431 , A61K45/06 , A61K39/085 , A61K9/00 , A61P31/04 , A01N31/00 , A01N41/10 , C12N1/18 , C12N1/20 , C12N1/38 , C12P7/06 , C12P7/56
CPC分类号： C12N1/38 , A01N41/10 , A61K9/0014 , A61K31/10 , A61K31/43 , A61K31/431 , A61K31/437 , A61K45/06 , C12N1/18 , C12N1/20 , C12P7/06 , C12P7/56 , Y02A50/406 , Y02A50/409 , Y02A50/411 , Y02A50/473 , Y02E50/17 , Y02E50/343 , A61K2300/00
摘要： Disclosed herein are methods of use of methylsulfonylmethane (MSM) to modulate microbial activity, such as to enhance or inhibit the activity of microorganisms. In one example, MSM (such as about 0.5% to 5% MSM) is used to enhance fermentation efficiency, such as to enhance fermentation efficiency associated with the production of beer, cider, wine, a biofuel, dairy product or any combination thereof. Also disclosed are in vitro methods for enhancing the growth of one or more probiotic microorganisms and methods of enhancing growth of a microorganism in a diagnostic test sample. Methods of inhibiting microbial activity are also disclosed. In one particular example, a method of inhibiting microbial activity includes selecting a medium that is susceptible to H1N1 influenza contamination; and contacting the medium with MSM at a concentration of about 10% to about 16% of weight by volume, thereby inhibiting H1N1 influenza microbial activity.
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公开(公告)号：EP2726599B1
公开(公告)日：2018-04-18
申请号：EP12805262.8
申请日：2012-06-28
发明人： BIELINSKI, Vincent, A. , BAUMAN, Nicholas , BOYD, Kate, Lyons , AKELLA, Srividya , BOWER, Stanley , ROESSLER, Paul, G.
摘要： The present invention relates to the regulation of a toxin and/or antitoxin genes in a genetically engineered microorganism, such as cyanobacterial or eukaryotic algal strains, in particular for preventing unintentional and/or uncontrolled spread of the microorganisms. The present invention also includes methods of controlling the growth and/or survival of the engineered microorganism
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公开(公告)号：EP1991659B1
公开(公告)日：2018-04-04
申请号：EP07710402.4
申请日：2007-01-30
摘要： The present invention is directed to methods for inducing desired activity in enzymes or microorganisms capable of producing the enzymes. The invention is further directed to methods of stabilizing activity in microorganisms. In specific embodiments, the invention provides methods for inducing and stabilizing nitrile hydratase activity, amidase activity, and asparaginase I activity. The invention further provides compositions comprising enzymes or microorganisms having induced and/or stabilized activity.
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公开(公告)号：EP3008166B1
公开(公告)日：2018-02-14
申请号：EP14729953.1
申请日：2014-05-14
申请人： Hemarina
发明人： ZAL, Franck
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9.发明公开WASCH- ODER REINIGUNGSMITTEL MIT SPEZIELLER ALPHA-AMYLASE UND DEFINIERTER WASSERAKTIVITÄT 审中-公开WASCH-ODER REINIGUNGSMITTEL MIT SPEZIELLER ALPHA-AMYLASE UND DEFINIERTERWASSERAKTIVITÄT
公开(公告)号：EP3230427A1
公开(公告)日：2017-10-18
申请号：EP15790155.4
申请日：2015-11-05
申请人： Henkel AG & Co. KGaA
发明人： ANTIR, Marouane , SCHÜMANN, Sabine , BASTIGKEIT, Thorsten , SEILER, Martina , O'CONNELL, Timothy , MEIER, Frank , WEINRICH, Dirk , KÖLLING, Leyla , BELLOMI, Luca , EDWARDS, Sheila
CPC分类号： C11D3/386 , C11D3/38618 , C12N1/20 , C12N1/38 , C12N9/00 , C12N9/2417 , C12N15/00
摘要： The invention relates to liquid compositions, in particular for cleaning textiles, containing: (a) at least one surfactant, and (b) at least one α-amylase, which is at least 89% and increasing preferably at least 90%, 90.5%, 91%, 91.5%, 92%, 92.5%, 93%, 93.5%, 94%, 94.5%, 95%, 95.5%, 96%, 96.5%, 97%, 97.5%, 98%, 98.5%, 99%, 99.5% and up to 100% identical to the sequence set forth in SEQ ID NO. 1 over the entire length thereof and has deletions at one or more of positions 180, 181, 182, 183, and 184 in the counting according to SEQ ID NO. 1, with the stipulation that the composition has a water activity (a
w ) between 0.3 and 0.95, in particular in a range of 0.4 to 0.95, at 25°C and 1013 mbar, stabilize in particular said amylase.摘要翻译： 本发明涉及特别用于清洁纺织品的液体组合物，其包含：（a）至少一种表面活性剂和（b）至少一种α-淀粉酶，其至少89％，优选至少90％，90.5％ ，91％，91.5％，92％，92.5％，93％，93.5％，94％，94.5％，95％，95.5％，96％，96.5％，97％，97.5％，98％，98.5％，99 ％，99.5％和至多100％相同于SEQ ID NO.2所示的序列。 1，并且在根据SEQ ID NO.1的计数中在180,181,182,183和184位中的一个或多个处具有缺失。 1，其中规定所述组合物在25℃和1013毫巴下具有0.3-0.95，特别是0.4-0.95的水活度（a w），特别是稳定所述淀粉酶。
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10.发明公开USE OF NITRIC OXIDE OR NITRIC OXIDE DONOR FOR INDUCING THE PRODUCTION OF TRIACYLGLYCEROLS IN MICROALGAE 审中-公开一氧化氮或一氧化氮供体用于诱导微藻生产三乙酰甘油的用途
公开(公告)号：EP3199620A1
公开(公告)日：2017-08-02
申请号：EP16305089.1
申请日：2016-01-29
申请人： COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES , Centre National de la Recherche Scientifique
发明人： MARECHAL, Eric , DOLCH, Lina-Juana
CPC分类号： C12P7/649 , C12N1/12 , C12N1/38 , C12P7/6454 , C12P7/6463
摘要： The invention relates to a method for triggering triacylglycerols (TAG) accumulation in microalgae comprising the step of contacting a source of exogenous nitroxide (NO) with said microalgae in their growth medium.
摘要翻译： 本发明涉及触发微藻中三酰甘油（TAG）积累的方法，包括使外源性氮氧化物（NO）源与所述微藻在其生长培养基中接触的步骤。
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