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公开(公告)号：EP4410991A3
公开(公告)日：2024-10-09
申请号：EP24183263.3
申请日：2010-12-16
发明人： XU, Jean
IPC分类号： C12N5/071 , C12N5/0735 , C12Q1/68
CPC分类号： C12N2501/11720130101 , C12N2501/1620130101 , C12N2501/4120130101 , C12N2501/41520130101 , C12N2501/7020130101 , C12N2506/0220130101 , C12N2533/9020130101 , C12N5/0676 , A61P5/48
摘要： The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present invention provides a method to produce cells expressing markers characteristic of the pancreatic endocrine lineage that co-express NKX6.1 and insulin and minimal amounts of glucagon.
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公开(公告)号：EP4423254A1
公开(公告)日：2024-09-04
申请号：EP22888221.3
申请日：2022-10-28
IPC分类号： C12N5/0797 , A61K35/30
CPC分类号： C12N5/0037 , C12N5/0676 , C12N5/0626 , C12N5/0619 , C12N2506/0220130101 , C12N2506/4520130101 , C12N2510/0020130101 , C12N2513/0020130101 , C12N2501/0120130101 , C12N2501/11520130101 , C12N2501/11720130101 , C12N2501/12520130101 , C12N2501/1520130101 , C12N2501/15520130101 , C12N2501/1320130101 , C12N2500/2520130101 , C12N2501/41520130101 , C12N2501/36520130101 , C12N2501/38520130101 , C12N2501/9120130101 , C12N2501/72720130101 , C12N2501/1620130101 , C12N2533/9020130101 , C12N2533/5220130101 , C12N2501/7220130101 , C12N2501/8020130101 , G01N33/5058 , G01N33/5026
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公开(公告)号：EP4416268A1
公开(公告)日：2024-08-21
申请号：EP22879700.7
申请日：2022-10-14
发明人： BATEMAN, John , LAMANDÉ, Shireen , NG, Elizabeth
CPC分类号： A61P19/02 , A61L2430/0620130101 , A61L2300/6420130101 , A61L27/3817 , A61L27/3895 , G01N33/5044 , G01N2500/1020130101 , C12N5/0655 , C12N2501/11520130101 , C12N2501/1620130101 , C12N2501/41520130101 , C12N2501/72720130101 , C12N2501/15520130101 , C12N2501/4120130101 , C12N2506/4520130101 , C12N2506/1320130101 , C12N2501/39520130101 , C12N2501/1520130101 , C12N2513/0020130101 , C12N2500/9520130101 , C12N5/0654 , A61K35/545
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公开(公告)号：EP4121512B1
公开(公告)日：2024-08-21
申请号：EP21712188.8
申请日：2021-03-19
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公开(公告)号：EP3625331B1
公开(公告)日：2024-07-10
申请号：EP18802136.4
申请日：2018-05-18
IPC分类号： C12N5/074 , C12N5/0789 , C12N5/071 , G01N33/50 , A01K67/027
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公开(公告)号：EP2516625B1
公开(公告)日：2024-06-26
申请号：EP10840005.2
申请日：2010-12-16
IPC分类号： C12N5/071 , C12N5/0735 , C12Q1/68
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公开(公告)号：EP4363556A1
公开(公告)日：2024-05-08
申请号：EP22834204.4
申请日：2022-06-30
CPC分类号： C12N5/068 , C12N5/0662 , C12N5/0623 , C12N2506/4520130101 , C12N2501/1520130101 , C12N2501/41520130101 , C12N2501/15520130101 , C12N2510/0020130101 , C12N2513/0020130101 , C12N5/0697 , A61K35/38 , C12N2502/08820130101 , C12N2501/1120130101 , C12N2501/11520130101 , C12N2501/11920130101 , C12N2501/1620130101 , C12N2501/72720130101 , C12N2533/9020130101
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公开(公告)号：EP3440192B1
公开(公告)日：2024-10-02
申请号：EP17779928.5
申请日：2017-04-07
IPC分类号： C12N5/071 , A61K35/39 , A61K35/545 , A61P3/10 , A61P5/48
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公开(公告)号：EP4416267A1
公开(公告)日：2024-08-21
申请号：EP22881769.8
申请日：2022-10-13
发明人： LIM, Bing , GERAMI-NAINI, Behzad , DU, Qiumei , WANG, Stan
CPC分类号： C12N2506/4520130101 , C12N2513/0020130101 , C12N2533/9020130101 , C12N2501/1120130101 , C12N2501/15520130101 , C12N2501/4120130101 , C12N2501/72720130101 , C12N2501/11920130101 , C12N2500/2520130101 , C12N2501/1620130101 , C12N2501/38520130101 , C12N5/065 , C12N2501/41520130101 , C12N2501/2520130101 , A61K35/545 , A61P35/00
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10.发明公开
公开(公告)号：EP4345160A3
公开(公告)日：2024-07-03
申请号：EP23214033.5
申请日：2016-09-07
申请人： The United States of America, as represented by The Secretary, Department of Health and Human Services , FUJIFILM Cellular Dynamics, Inc.
IPC分类号： C12N5/079
CPC分类号： C12N2501/10520130101 , C12N2501/1520130101 , C12N2501/15520130101 , C12N2501/1620130101 , C12N2501/41520130101 , C12N2506/4520130101 , C12N2533/5020130101 , C12N2533/5220130101 , C12N5/0621
摘要： Provided herein are methods of producing an RPE cell population from a starting cell suspension, such as a single cell suspension, of pluripotent stem cells (PSCs). Such a method may comprise culturing the starting single cell suspension of PSCs in differentiation media to produce human RPE cells.
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