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1.发明授权CRIMEAN-CONGO HAEMORRHAGIC FEVER VIRUS ANTIGENIC COMPOSITION 有权CRIMEAN-CONGO HAEMORRHAGIC FEVER VIRUS抗原组合物
公开(公告)号：EP2961846B1
公开(公告)日：2018-01-10
申请号：EP13802091.2
申请日：2013-11-29
发明人： BUTTIGIEG, Karen , CARROLL, Miles , HEWSON, Roger , DOWALL, Stuart , FINDLAY-WILSON, Stephen , MILOSZEWSKA, Aleksandra
IPC分类号： C12N15/863 , C12N15/861 , C12N15/70 , C12N15/40 , C12N5/10 , A61K39/12
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K2039/523 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , C12N7/00 , C12N15/86 , C12N2710/10341 , C12N2710/24041 , C12N2710/24141 , C12N2760/12034
摘要： The present invention provides a viral vector or bacterial vector, said vector comprising a nucleic acid sequence encoding a Crimean-Congo Haemorrhagic Fever Virus (CCHFV) glycoprotein or antigenic fragment thereof; wherein said vector is capable of inducing an immune response in a subject. The present invention also provides compositions and uses of the vector in methods of medical treatment.
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公开(公告)号：EP2117590B1
公开(公告)日：2011-06-22
申请号：EP07857167.6
申请日：2007-12-31
申请人： Pevion Biotech Ltd.
IPC分类号： A61K39/145
CPC分类号： A61K39/145 , A61K39/0225 , A61K39/12 , A61K2039/5258 , A61K2039/53 , A61K2039/585 , C12N2760/12034 , C12N2760/16134 , C12N2760/16142
摘要： The present invention relates to the use of a lipid vesicle for the preparation of a medicament. The invention further relates to a method of treating and/or preventing a disease or disorder involving administering such a lipid vesicle to an animal in need thereof.
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公开(公告)号：EP2618839B1
公开(公告)日：2018-05-02
申请号：EP11760878.6
申请日：2011-09-20
IPC分类号： A61K39/12 , C12N7/00 , C07K14/175
CPC分类号： C12N7/00 , A61K39/12 , C07K14/005 , C12N2510/02 , C12N2760/12022 , C12N2760/12034 , C12N2760/12043 , C12N2760/12051 , C12N2760/12221 , C12N2760/12233 , C12N2760/12234 , Y02A50/397
摘要： The invention relates to methods of producing infectious bunyavirus replicon particles. These bunyavirus replicon particles are safe and can be used outside a biosafety containment. The invention further relates to recombinant bunyavirus replicon particles and uses of these recombinant bunyavirus replicon particles.
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4.发明授权SCHMALLENBERG VIRUS (SBV) VACCINE, METHODS OF PRODUCTION, AND USES THEREOF 有权施马伦贝格病毒（SBV）疫苗，制备和使用方法
公开(公告)号：EP2855513B1
公开(公告)日：2016-12-07
申请号：EP13728288.5
申请日：2013-05-29
发明人： NIKOLIN, Veljko , STADLER, Konrad , LISCHEWSKI, Axel , BRIX, Alexander , KNITTEL, Jeffrey P. , TOEPFER, Katharina Hedwig
IPC分类号： C07K14/175 , A61K39/12
CPC分类号： A61K39/12 , A61K35/76 , A61K47/22 , A61K2039/5252 , A61K2039/545 , A61K2039/552 , A61K2039/55505 , A61K2039/55577 , C07K7/00 , C12N2760/12021 , C12N2760/12022 , C12N2760/12034 , C12N2760/12063
摘要： The present invention relates to the field of vaccines and medicaments for the prophylaxis and treatment of infectious diseases in ruminants. In particular, it relates to inactivated Schmallenberg virus (SBV) useful as vaccine or medicament for preventing or treating viremia, the transmission and clinical symptoms, in particular malformations in newborn ruminants such as cattle, sheep and goats, induced by SBV.
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5.发明公开REVERSE GENETICS SCHMALLENBERG VIRUS VACCINE COMPOSITIONS, AND METHODS OF USE THEREOF 审中-公开通过反向遗传学生产的疫苗组合物AGAINST施马伦贝格病毒及其使用方法
公开(公告)号：EP2968514A1
公开(公告)日：2016-01-20
申请号：EP14717275.3
申请日：2014-03-11
申请人： Merial, Inc.
CPC分类号： C12N7/00 , A61K39/12 , A61K2039/5252 , A61K2039/552 , A61K2039/55505 , A61K2039/55566 , A61K2039/55577 , C12N2760/12021 , C12N2760/12034
摘要： The present invention relates to compositions comprising replication defective Schmallenberg virus vaccines, methods of producing the vaccines, and the administration of such vaccines to animals, including ovines and bovines. The invention further relates to methods for providing long-term protective immunity against Schmallenberg in animals, including ovines and bovines.
摘要翻译： 本发明涉及组合物，其包括复制缺陷施马伦贝格病毒疫苗，制备疫苗的方法，和疫苗的动物的检查的管理，包括绵羊和牛。 本发明还涉及一种用于在动物抵御施马伦贝格提供长期的保护性免疫力，包括绵羊和牛的方法。
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公开(公告)号：EP1237571B1
公开(公告)日：2007-09-26
申请号：EP00987600.4
申请日：2000-12-18
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , C12N2760/12022 , C12N2760/12034
摘要： Surprinsingly, it has been discovered that the core protein antigen of Toscana virus can induce a protective humoral response. The invention relates to compositions comprising Toscana virus nucleoprotein. These may be used in the treatment or prophylaxis of Toscana virus infection. Also provided is the use of an internal virus antigen in the manufacture of a medicament for eliciting a neutralising humoral anti-viral immune response.
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7.发明授权BUNYAVIRUSES WITH SEGMENTED GLYCOPROTEIN PRECURSOR GENES AND METHODS FOR GENERATING THESE VIRUSES 有权具有分枝糖蛋白前体基因的BUNYAVIRUS及其产生这些病毒的方法
公开(公告)号：EP2999781B1
公开(公告)日：2018-02-21
申请号：EP14729458.1
申请日：2014-05-21
发明人： KORTEKAAS, Jeroen Alexander , WICHGERS SCHREUR, Paulus-Jozef , ORESHKOVA, Nadia Dimitrova , MOORMANN, Robertus Jacobus Maria
IPC分类号： C12N7/00
CPC分类号： A61K39/12 , A61K2039/525 , C12N7/00 , C12N2760/12034 , C12N2760/12221 , C12N2760/12234 , C12N2760/12243 , C12N2760/12262
摘要： The invention relates to a bunyavirus, in which separated (NSm)Gn and Gc coding regions are functionally present on two different genome segments, preferably a bunyavirus that comprises a total of at least 4 genome segments. The invention further relates to methods for producing said bunyavirus, and to a composition comprising said bunyavirus and a suitable excipient.
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公开(公告)号：EP2766038B1
公开(公告)日：2016-03-02
申请号：EP13785956.7
申请日：2013-09-03
申请人： Firat Üniversitesi
IPC分类号： A61K39/12
CPC分类号： A61K39/12 , A61K2039/5252 , A61K2039/55505 , C12N2760/12034
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9.发明公开ATTENUATED LIVE VACCINE FOR CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS AND ERVE VIRUS 审中-公开减毒活疫苗的克里米亚刚果出血热及ERVE病毒
公开(公告)号：EP2884998A1
公开(公告)日：2015-06-24
申请号：EP13829120.8
申请日：2013-08-13
申请人： Colorado Seminary which owns and operates The University of Denver , The United States of America as Represented by the Secretary, Department of Health and Human Services
CPC分类号： A61K39/12 , A61K2039/5254 , C12N2760/12034 , Y02A50/397
摘要： The genetically modified hemorrhagic fever virus of this invention possesses a viral ovarian tumor protease with decreased ability to remove ubiquitin (Ub) and ISG15 tags that the human organism uses to label proteins for removal. Unlike complete knockout strains, the modified virus retains enough activity for replication in a human cell line. This creates an immunogenic and non-pathogenic virus that can be used as an effective live vaccine agent.
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10.发明公开METHODS AND REAGENTS FOR TREATING, PREVENTING AND DIAGNOSING BUNYAVIRUS INFECTION 审中-公开方法和试剂BEHANDLUND预防与感染布尼亚病毒的诊断
公开(公告)号：EP1689347A4
公开(公告)日：2009-01-14
申请号：EP04811957
申请日：2004-11-19
发明人： CHOO QUI-LIM , HOUGHTON MICHAEL , SCOTT ELIZABETH , WEINER AMY
IPC分类号： A61K39/12 , A61K20060101 , C07H19/00 , C07K14/175 , C12Q1/70
CPC分类号： C07K14/005 , A61K39/12 , A61K2039/55566 , C12N2760/12022 , C12N2760/12034
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