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公开(公告)号：EP2736522A1
公开(公告)日：2014-06-04
申请号：EP12746431.1
申请日：2012-07-27
发明人： WRIGHT, Jason , BRADFORD, Marc , SUGAR, Frank , DAVIES, Tim , MILLSAP, Kevin
CPC分类号： C12N7/00 , A61K35/76 , C12N7/02 , C12N2795/00051 , C12N2795/14151
摘要： The invention relates to culture conditions and methods that allow reproducible production of high titers of filamentous bacteriophage. Culture media comprising high titers of filamentous bacteriophage, as we methods of producing high titers of filamentous phage on a large scale are encompassed.
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2.发明公开PURE FILAMENTOUS BACTERIOPHAGE AND METHODS OF PRODUCING SAME 审中-公开REINFILAMENTÖSERBAKTERIOPHAGE UND HERSTELLUNGSVERFAHRENDAFÜR
公开(公告)号：EP2739294A1
公开(公告)日：2014-06-11
申请号：EP12746448.5
申请日：2012-08-03
发明人： WRIGHT, Jason , HITCHCOCK, Antony , SUGAR, Frank , DAVIES, Tim , ADHIKARI, Shreekant , MENON, Nanda , FLORENCE, Quentin
CPC分类号： A61K35/76 , A61K2035/11 , C12N7/00 , C12N2795/00032 , C12N2795/14151 , Y10S977/773
摘要： The invention relates to compositions of purified filamentous bacteriophage, as well as methods that allow reproducible purification of high concentrations of filamentous bacteriophage.
摘要翻译： 本发明涉及纯化的丝状噬菌体的组合物，以及允许可重复纯化高浓度丝状噬菌体的方法。
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3.发明公开METHOD TO ISOLATE MACROMOLECULES USING MAGNETICALLY ATTRACTABLE BEADS WHICH DO NOT SPECIFICALLY BIND THE MACROMOLECULES 失效METHOD FOR THAT大分子非特异性结合磁性吸引球的大分子MEANS的分离。
公开(公告)号：EP0515484A1
公开(公告)日：1992-12-02
申请号：EP91904432.0
申请日：1991-02-13
发明人： REEVE, Michael, Alan
CPC分类号： C12N7/00 , B03C1/01 , C07H1/06 , C07K1/30 , C07K1/34 , C12N1/02 , C12N15/1013 , C12N2795/14151
摘要： Un procédé de récupération d'un biopolymère dans une solution consiste à utiliser des sphères pouvant subir une attraction magnétique et qui ne font pas de liaison spécifique avec le polymère. Les sphères sont suspendues dans la solution. Ensuite le polymère présent dans la solution est précipité et assume une association non spécifique avec les sphères. Lorsque les sphères sont attirées magnétiquement vers le bas, le polymère est entraîné avec elles. Le polymère peut ensuite être resolubilisé et séparé des sphères.
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4.发明授权
公开(公告)号：EP2720768B1
公开(公告)日：2017-04-12
申请号：EP12726916.5
申请日：2012-06-01
CPC分类号： C07K14/75 , B01D15/08 , B01D15/166 , B01D15/1807 , B01D15/34 , B01D15/363 , B01D15/3885 , C07K1/16 , C07K14/755 , C07K16/00 , C07K16/065 , C12N7/00 , C12N2795/00 , C12N2795/14151
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5.发明公开CHROMATOGRAPHIC PURIFICATION OF VIRUS PREPARATIONS WITH NEGATIVELY CHARGED PARTICLES 审中-公开色谱清洗的，带负电荷的粒子病毒制备
公开(公告)号：EP2958995A2
公开(公告)日：2015-12-30
申请号：EP13875750.5
申请日：2013-02-22
发明人： GAGNON, Peter
IPC分类号： C12N7/02
CPC分类号： C12N7/00 , B01D15/22 , B01D15/34 , B01D15/362 , B01D15/363 , B01D15/3847 , B01D15/424 , B01D61/145 , C12N2710/00051 , C12N2750/00051 , C12N2795/10151 , C12N2795/14151
摘要： A method of purifying a sample that includes a desired virus includes the steps of (i) providing a packed chromatographic column having negatively charged porous particles, (ii) equilibrating the column to the conditions to which the desired virus in the sample is to elute, (iii) contacting the sample with the packed chromatographic column such that the sample volume applied to the packed chromatographic column is less than or equal to the interparticle space of the negatively charged porous particles within the packed chromatographic column, (iv) eluting the desired virus from the packed chromatographic column, where the desired virus is in a purer state and in the conditions to which the packed chromatographic column was equilibrated.
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公开(公告)号：EP1578960A1
公开(公告)日：2005-09-28
申请号：EP02808210.5
申请日：2002-12-31
发明人： ZHANG, Xu , XIE, Xin , CHEN, Depu , FEI, Weiyang , CHENG, Jing
CPC分类号： G01N33/54333 , C12N1/02 , C12N7/00 , C12N2760/16051 , C12N2795/14151 , C12Q1/24 , G01N33/54326
摘要： This invention relates generally to the field of. In particular, the invention provides processes and kits for isolating a target cell, cellular organelle or virus from a sample, using inter alia, non- or low-specific binding between a target cell, cellular organelle or virus with a magnetic microbead.
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7.发明公开CHROMATOGRAPHIC PURIFICATION OF VIRUS PREPARATIONS WITH NEGATIVELY CHARGED PARTICLES 审中-公开色谱清洗的，带负电荷的粒子病毒制备
公开(公告)号：EP2958995A4
公开(公告)日：2016-11-23
申请号：EP13875750
申请日：2013-02-22
发明人： GAGNON PETER
CPC分类号： C12N7/00 , B01D15/22 , B01D15/34 , B01D15/362 , B01D15/363 , B01D15/3847 , B01D15/424 , B01D61/145 , C12N2710/00051 , C12N2750/00051 , C12N2795/10151 , C12N2795/14151
摘要： A method of purifying a sample that includes a desired virus includes the steps of (i) providing a packed chromatographic column having negatively charged porous particles, (ii) equilibrating the column to the conditions to which the desired virus in the sample is to elute, (iii) contacting the sample with the packed chromatographic column such that the sample volume applied to the packed chromatographic column is less than or equal to the interparticle space of the negatively charged porous particles within the packed chromatographic column, (iv) eluting the desired virus from the packed chromatographic column, where the desired virus is in a purer state and in the conditions to which the packed chromatographic column was equilibrated.
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8.发明公开PURIFICATION OF BIOLOGICAL PRODUCTS BY CONSTRAINED COHYDRATION CHROMATOGRAPHY 有权ON ON V ON UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG UNG
公开(公告)号：EP2720768A1
公开(公告)日：2014-04-23
申请号：EP12726916.5
申请日：2012-06-01
CPC分类号： C07K14/75 , B01D15/08 , B01D15/166 , B01D15/1807 , B01D15/34 , B01D15/363 , B01D15/3885 , C07K1/16 , C07K14/755 , C07K16/00 , C07K16/065 , C12N7/00 , C12N2795/00 , C12N2795/14151
摘要： Materials and methods for use of constrained cohydration agents in the purification of biological materials such as antibodies, viruses, cells, and cellular organelles in connection with convective chromatography, fluidized bed or co-precipitation applications.
摘要翻译： 在与对流色谱法，流化床或共沉淀应用有关的生物材料如抗体，病毒，细胞和细胞器的纯化中使用受限制的辅助水化剂的材料和方法。
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9.发明授权METHOD TO ISOLATE MACROMOLECULES USING MAGNETICALLY ATTRACTABLE BEADS WHICH DO NOT SPECIFICALLY BIND THE MACROMOLECULES 失效METHOD FOR THAT大分子非特异性结合磁性吸引球的大分子MEANS的分离。
公开(公告)号：EP0515484B1
公开(公告)日：1995-04-26
申请号：EP91904432.1
申请日：1991-02-13
发明人： REEVE, Michael, Alan
CPC分类号： C12N7/00 , B03C1/01 , C07H1/06 , C07K1/30 , C07K1/34 , C12N1/02 , C12N15/1013 , C12N2795/14151
摘要： A method of recovering a biopolymer from solution involves the use of magnetically attractable beads which do not specifically bind the polymer. The beads are suspended in the solution. Then the polymer is precipitated out of solution and becomes non-specifically associated with the beads. When the beads are magnetically drawn down, the polymer is drawn down with them. The polymer can subsequently be resolubilised and separated from the beads.
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10.发明公开
公开(公告)号：EP3210662A1
公开(公告)日：2017-08-30
申请号：EP17165356.1
申请日：2012-06-01
CPC分类号： C07K14/75 , B01D15/08 , B01D15/166 , B01D15/1807 , B01D15/34 , B01D15/363 , B01D15/3885 , C07K1/16 , C07K14/755 , C07K16/00 , C07K16/065 , C12N7/00 , C12N2795/00 , C12N2795/14151
摘要： Materials and methods for use of constrained cohydration agents in the purification of biological materials such as antibodies, viruses, cells, and cellular organelles in connection with convective chromatography, fluidized bed or co-precipitation applications.
摘要翻译： 在对流层析，流化床或共沉淀应用中使用受限制的共水化剂纯化生物材料如抗体，病毒，细胞和细胞器的材料和方法。
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