公开(公告)号：EP2764111A2

公开(公告)日：2014-08-13

申请号：EP12780579.4

申请日：2012-10-05

申请人： The Procter & Gamble Company

发明人： XU, Jun ,  SAUNDERS, Charles, Winston ,  GREEN, Phillip, Richard ,  VELASQUEZ, Juan, Esteban

IPC分类号： C12P7/40 ,  C12P7/52 ,  C12P7/42 ,  C12P7/24 ,  C12P7/62

CPC分类号： C12P7/52 ,  C12N9/0004 ,  C12P7/18 ,  C12P7/24 ,  C12P7/40 ,  C12P7/42 ,  C12P7/625 ,  C12P19/32 ,  C12Y102/01003 ,  C12Y102/04002 ,  C12Y104/01005 ,  C12Y104/03002 ,  C12Y104/03003 ,  C12Y401/01072

摘要： This invention relates to microorganisms that convert a carbon source to acrylate or other desirable products using homoserine and 2-keto-4-hydroxybutyrate as intermediates. The invention provides genetically engineered microorganisms that carry out the conversion, as well as methods for producing acrylate by culturing the microorganisms. Also provided are microorganisms and methods for converting homoserine to 3-hydroxypropionyl-CoA, 3-hydroxypropionate (3HP), poly-3-hydroxypropionate and 1,3-propanediol.

公开(公告)号：EP2930244A1

公开(公告)日：2015-10-14

申请号：EP14163770.2

申请日：2014-04-07

申请人： The Procter & Gamble Company

发明人： Xu, Jun ,  Saunders, Charles ,  Green, Phillip ,  Velasquez, Juan

IPC分类号： C12P19/26 ,  C12P7/42 ,  C12P7/52 ,  C12P7/62

CPC分类号： C12P7/52 ,  C12N9/1096 ,  C12P7/18 ,  C12P7/24 ,  C12P7/42 ,  C12Y104/01005 ,  C12Y104/03002 ,  C12Y206/01001 ,  C12Y206/01002

摘要： The invention relates to a micro-organism that is able to convert homoserine to 3-hydroxypropionaldehyde, wherein the micro-organism expresses a protein capable of converting homoserine to 2-keto-4-hydroxybutyrate wherein the protein is selected from the group consisting of: aminotransferases, an amino acid oxidases, and amino acid dehydrogenases.

摘要翻译： 本发明涉及一种微生物确实能够高丝氨酸转化为3-羟基丙醛，worin微生物快车能够将高丝氨酸为2-酮-4-羟基丁酸酯组成的蛋白质worin将蛋白质从所述组包括选自： 转氨酶氨基酸氧化酶和氨基酸脱氢酶。